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Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis
Takasato, Minoru, Er, Pei X., Chiu, Han S., Maier, Barbara, Baillie, Gregory J., Ferguson, Charles, Parton, Robert G., Wolvetang, Ernst J., Roost, Matthias S., Chuva de Sousa Lopes, Susana M., Little, Melissa H.
Published in Nature (London) (22.10.2015)
Published in Nature (London) (22.10.2015)
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Journal Article
Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development
Hochane, Mazène, van den Berg, Patrick R., Fan, Xueying, Bérenger-Currias, Noémie, Adegeest, Esmée, Bialecka, Monika, Nieveen, Maaike, Menschaart, Maarten, Chuva de Sousa Lopes, Susana M., Semrau, Stefan
Published in PLoS biology (01.02.2019)
Published in PLoS biology (01.02.2019)
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Journal Article
DNA Methylation Landscapes of Human Fetal Development
Slieker, Roderick C., Roost, Matthias S., van Iperen, Liesbeth, Suchiman, H. Eka D., Tobi, Elmar W., Carlotti, Françoise, de Koning, Eelco J. P., Slagboom, P. Eline, Heijmans, Bastiaan T., Chuva de Sousa Lopes, Susana M.
Published in PLoS genetics (01.10.2015)
Published in PLoS genetics (01.10.2015)
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Journal Article
Generating high-fidelity cochlear organoids from human pluripotent stem cells
Moore, Stephen T., Nakamura, Takashi, Nie, Jing, Solivais, Alexander J., Aristizábal-Ramírez, Isabel, Ueda, Yoshitomo, Manikandan, Mayakannan, Reddy, V. Shweta, Romano, Daniel R., Hoffman, John R., Perrin, Benjamin J., Nelson, Rick F., Frolenkov, Gregory I., Chuva de Sousa Lopes, Susana M., Hashino, Eri
Published in Cell stem cell (06.07.2023)
Published in Cell stem cell (06.07.2023)
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Journal Article
Piwi Proteins and piRNAs in Mammalian Oocytes and Early Embryos
Roovers, Elke F., Rosenkranz, David, Mahdipour, Mahdi, Han, Chung-Ting, He, Nannan, Chuva de Sousa Lopes, Susana M., van der Westerlaken, Lucette A.J., Zischler, Hans, Butter, Falk, Roelen, Bernard A.J., Ketting, René F.
Published in Cell reports (Cambridge) (31.03.2015)
Published in Cell reports (Cambridge) (31.03.2015)
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Journal Article
Rethinking organoid technology through bioengineering
Garreta, Elena, Kamm, Roger D., Chuva de Sousa Lopes, Susana M., Lancaster, Madeline A., Weiss, Ron, Trepat, Xavier, Hyun, Insoo, Montserrat, Nuria
Published in Nature materials (01.02.2021)
Published in Nature materials (01.02.2021)
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Journal Article
Derivation of pluripotent epiblast stem cells from mammalian embryos
Brons, I. Gabrielle M., Smithers, Lucy E., Trotter, Matthew W. B., Rugg-Gunn, Peter, Sun, Bowen, Chuva de Sousa Lopes, Susana M., Howlett, Sarah K., Clarkson, Amanda, Ahrlund-Richter, Lars, Pedersen, Roger A., Vallier, Ludovic
Published in Nature (12.07.2007)
Published in Nature (12.07.2007)
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Journal Article
Strand-specific single-cell methylomics reveals distinct modes of DNA demethylation dynamics during early mammalian development
Sen, Maya, Mooijman, Dylan, Chialastri, Alex, Boisset, Jean-Charles, Popovic, Mina, Heindryckx, Björn, Chuva de Sousa Lopes, Susana M., Dey, Siddharth S., van Oudenaarden, Alexander
Published in Nature communications (24.02.2021)
Published in Nature communications (24.02.2021)
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Journal Article
Parental haplotype-specific single-cell transcriptomics reveal incomplete epigenetic reprogramming in human female germ cells
Vértesy, Ábel, Arindrarto, Wibowo, Roost, Matthias S., Reinius, Björn, Torrens-Juaneda, Vanessa, Bialecka, Monika, Moustakas, Ioannis, Ariyurek, Yavuz, Kuijk, Ewart, Mei, Hailiang, Sandberg, Rickard, van Oudenaarden, Alexander, Chuva de Sousa Lopes, Susana M.
Published in Nature communications (14.05.2018)
Published in Nature communications (14.05.2018)
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Journal Article
DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells
Roost, Matthias S., Slieker, Roderick C., Bialecka, Monika, van Iperen, Liesbeth, Gomes Fernandes, Maria M., He, Nannan, Suchiman, H. Eka D., Szuhai, Karoly, Carlotti, Françoise, de Koning, Eelco J. P., Mummery, Christine L., Heijmans, Bastiaan T., Chuva de Sousa Lopes, Susana M.
Published in Nature communications (13.10.2017)
Published in Nature communications (13.10.2017)
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Journal Article
Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids
Velazquez, Jeremy J., LeGraw, Ryan, Moghadam, Farzaneh, Tan, Yuqi, Kilbourne, Jacquelyn, Maggiore, Joseph C., Hislop, Joshua, Liu, Silvia, Cats, Davy, Chuva de Sousa Lopes, Susana M., Plaisier, Christopher, Cahan, Patrick, Kiani, Samira, Ebrahimkhani, Mo R.
Published in Cell systems (20.01.2021)
Published in Cell systems (20.01.2021)
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Journal Article
Transcriptional progression during meiotic prophase I reveals sex-specific features and X chromosome dynamics in human fetal female germline
Fan, Xueying, Moustakas, Ioannis, Torrens-Juaneda, Vanessa, Lei, Qijing, Hamer, Geert, Louwe, Leoni A., Pilgram, Gonneke S. K., Szuhai, Karoly, Matorras, Roberto, Eguizabal, Cristina, Westerlaken, Lucette van der, Mei, Hailiang, Chuva de Sousa Lopes, Susana M.
Published in PLoS genetics (09.09.2021)
Published in PLoS genetics (09.09.2021)
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Journal Article
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
Hu, Huili, Gehart, Helmuth, Artegiani, Benedetta, LÖpez-Iglesias, Carmen, Dekkers, Florijn, Basak, Onur, van Es, Johan, Chuva de Sousa Lopes, Susana M., Begthel, Harry, Korving, Jeroen, van den Born, Maaike, Zou, Chenhui, Quirk, Corrine, Chiriboga, Luis, Rice, Charles M., Ma, Stephanie, Rios, Anne, Peters, Peter J., de Jong, Ype P., Clevers, Hans
Published in Cell (29.11.2018)
Published in Cell (29.11.2018)
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Journal Article
Immune Dysregulation and Trophoblastic Dysfunction as a Potential Cause of Idiopathic Recurrent Pregnancy Loss
Vasconcelos, Sara, Braga, Ana Costa, Moustakas, Ioannis, Cavadas, Bruno, Santos, Mariana, Caniçais, Carla, Ramalho, Carla, Chuva de Sousa Lopes, Susana M., Marques, Cristina Joana, Dória, Sofia
Published in Biology (Basel, Switzerland) (04.07.2025)
Published in Biology (Basel, Switzerland) (04.07.2025)
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Journal Article
KeyGenes, a Tool to Probe Tissue Differentiation Using a Human Fetal Transcriptional Atlas
Roost, Matthias S., van Iperen, Liesbeth, Ariyurek, Yavuz, Buermans, Henk P., Arindrarto, Wibowo, Devalla, Harsha D., Passier, Robert, Mummery, Christine L., Carlotti, Françoise, de Koning, Eelco J.P., van Zwet, Erik W., Goeman, Jelle J., Chuva de Sousa Lopes, Susana M.
Published in Stem cell reports (09.06.2015)
Published in Stem cell reports (09.06.2015)
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Journal Article
Memory CD4+ T cells are generated in the human fetal intestine
Li, Na, van Unen, Vincent, Abdelaal, Tamim, Guo, Nannan, Kasatskaya, Sofya A., Ladell, Kristin, McLaren, James E., Egorov, Evgeny S., Izraelson, Mark, Chuva de Sousa Lopes, Susana M., Höllt, Thomas, Britanova, Olga V, Eggermont, Jeroen, de Miranda, Noel F. C. C., Chudakov, Dmitriy M., Price, David A., Lelieveldt, Boudewijn P. F., Koning, Frits
Published in Nature immunology (01.03.2019)
Published in Nature immunology (01.03.2019)
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Journal Article
Germ Cell Specification in Mice
Hayashi, Katsuhiko, de Sousa Lopes, Susana M. Chuva, Surani, M. Azim
Published in Science (American Association for the Advancement of Science) (20.04.2007)
Published in Science (American Association for the Advancement of Science) (20.04.2007)
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Journal Article