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Timely N-Acetyl-Cysteine and Environmental Enrichment Rescue Oxidative Stress-Induced Parvalbumin Interneuron Impairments via MMP9/RAGE Pathway: A Translational Approach for Early Intervention in Psychosis
Dwir, Daniella, Cabungcal, Jan-Harry, Xin, Lijing, Giangreco, Basilio, Parietti, Enea, Cleusix, Martine, Jenni, Raoul, Klauser, Paul, Conus, Philippe, Cuénod, Michel, Steullet, Pascal, Do, Kim Q
Published in Schizophrenia bulletin (01.11.2021)
Published in Schizophrenia bulletin (01.11.2021)
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Journal Article
Impaired glutathione synthesis in schizophrenia: Convergent genetic and functional evidence
Gysin, René, Kraftsik, Rudolf, Sandell, Julie, Bovet, Pierre, Chappuis, Céline, Conus, Philippe, Deppen, Patricia, Preisig, Martin, Ruiz, Viviane, Steullet, Pascal, Tosic, Mirjana, Werge, Thomas, Cuénod, Michel, Do, Kim Q
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2007)
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Journal Article
Glutathione Precursor, N-Acetyl-Cysteine, Improves Mismatch Negativity in Schizophrenia Patients
Lavoie, Suzie, Murray, Micah M, Deppen, Patricia, Knyazeva, Maria G, Berk, Michael, Boulat, Olivier, Bovet, Pierre, Bush, Ashley I, Conus, Philippe, Copolov, David, Fornari, Eleonora, Meuli, Reto, Solida, Alessandra, Vianin, Pascal, Cuénod, Michel, Buclin, Thierry, Do, Kim Q
Published in Neuropsychopharmacology (New York, N.Y.) (01.08.2008)
Published in Neuropsychopharmacology (New York, N.Y.) (01.08.2008)
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Journal Article
Characterization of early psychosis patients carrying a genetic vulnerability to redox dysregulation: a computational analysis of mechanism-based gene expression profile in fibroblasts
Giangreco, Basilio, Dwir, Daniella, Klauser, Paul, Jenni, Raoul, Golay, Philippe, Cleusix, Martine, Baumann, Philipp S., Cuénod, Michel, Conus, Philippe, Toni, Nicolas, Do, Kim Q.
Published in Molecular psychiatry (01.05.2023)
Published in Molecular psychiatry (01.05.2023)
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Journal Article
Schizophrenia and Oxidative Stress: Glutamate Cysteine Ligase Modifier as a Susceptibility Gene
Tosic, Mirjana, Ott, Jurg, Barral, Sandra, Bovet, Pierre, Deppen, Patricia, Gheorghita, Fulvia, Matthey, Marie-Louise, Parnas, Josef, Preisig, Martin, Saraga, Michael, Solida, Alessandra, Timm, Sally, Wang, August G., Werge, Thomas, Cuénod, Michel, Quang Do, Kim
Published in American journal of human genetics (01.09.2006)
Published in American journal of human genetics (01.09.2006)
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Journal Article
Curcumin, quercetin, and tBHQ modulate glutathione levels in astrocytes and neurons: importance of the glutamate cysteine ligase modifier subunit
Lavoie, Suzie, Chen, Ying, Dalton, Timothy P, Gysin, René, Cuénod, Michel, Steullet, Pascal, Do, Kim Q
Published in Journal of neurochemistry (01.03.2009)
Published in Journal of neurochemistry (01.03.2009)
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Journal Article
Transitory glutathione deficit during brain development induces cognitive impairment in juvenile and adult rats: Relevance to schizophrenia
Cabungcal, Jan-Harry, Preissmann, Delphine, Delseth, Caroline, Cuénod, Michel, Do, Kim Q., Schenk, Françoise
Published in Neurobiology of disease (01.06.2007)
Published in Neurobiology of disease (01.06.2007)
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Journal Article
Glutathione deficit during development induces anomalies in the rat anterior cingulate GABAergic neurons: Relevance to schizophrenia
Cabungcal, Jan-Harry, Nicolas, Dominique, Kraftsik, Rudolf, Cuénod, Michel, Do, Kim Q., Hornung, Jean-Pierre
Published in Neurobiology of disease (01.06.2006)
Published in Neurobiology of disease (01.06.2006)
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Journal Article
Dysconnection Topography in Schizophrenia Revealed with State-Space Analysis of EEG
Jalili, Mahdi, Lavoie, Suzie, Deppen, Patricia, Meuli, Reto, Do, Kim Q., Cuénod, Michel, Hasler, Martin, De Feo, Oscar, Knyazeva, Maria G.
Published in PloS one (24.10.2007)
Published in PloS one (24.10.2007)
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Journal Article
Benefits of adjunctive N-acetylcysteine in a sub-group of clozapine-treated individuals diagnosed with schizophrenia
Dean, Olivia M., Mancuso, Serafino G., Bush, Ashley I., Copolov, David, Do, Kim Q., Cuénod, Michel, Conus, Philippe, Rossell, Susan L., Castle, David J., Berk, Michael
Published in Psychiatry research (30.12.2015)
Published in Psychiatry research (30.12.2015)
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Journal Article
Development and chemical specificity of neurons : proceedings of the Schatzalp Symposium, September, 1978
Cuénod, M., Kreutzberg, Georg W., Bloom, Floyd E., European Molecular Biology Organization, International Neurobiology Society, Symposium on Development and Chemical Specificity of Neurons
Year of Publication 1979
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Year of Publication 1979
Book
Dopamine-induced oxidative stress in neurons with glutathione deficit: implication for schizophrenia
Grima, Gilbert, Benz, Beatrix, Parpura, Vladimir, Cuénod, Michel, Do, Kim Q.
Published in Schizophrenia research (01.08.2003)
Published in Schizophrenia research (01.08.2003)
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Journal Article
MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory/excitatory imbalance: a reverse translation study in schizophrenia patients
Dwir, Daniella, Giangreco, Basilio, Xin, Lijing, Tenenbaum, Liliane, Cabungcal, Jan-Harry, Steullet, Pascal, Goupil, Audrey, Cleusix, Martine, Jenni, Raoul, Chtarto, Abdelwahed, Baumann, Philipp S., Klauser, Paul, Conus, Philippe, Tirouvanziam, Rabindra, Cuenod, Michel, Do, Kim Q.
Published in Molecular psychiatry (01.11.2020)
Published in Molecular psychiatry (01.11.2020)
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Journal Article
Caught in vicious circles: a perspective on dynamic feed-forward loops driving oxidative stress in schizophrenia
Cuenod, Michel, Steullet, Pascal, Cabungcal, Jan-Harry, Dwir, Daniella, Khadimallah, Ines, Klauser, Paul, Conus, Philippe, Do, Kim Q.
Published in Molecular psychiatry (01.04.2022)
Published in Molecular psychiatry (01.04.2022)
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Journal Article
Mitochondrial, exosomal miR137-COX6A2 and gamma synchrony as biomarkers of parvalbumin interneurons, psychopathology, and neurocognition in schizophrenia
Khadimallah, Ines, Jenni, Raoul, Cabungcal, Jan-Harry, Cleusix, Martine, Fournier, Margot, Beard, Elidie, Klauser, Paul, Knebel, Jean-François, Murray, Micah M., Retsa, Chrysa, Siciliano, Milena, Spencer, Kevin M., Steullet, Pascal, Cuenod, Michel, Conus, Philippe, Do, Kim Q.
Published in Molecular psychiatry (01.02.2022)
Published in Molecular psychiatry (01.02.2022)
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Journal Article
A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons
Steullet, Pascal, Lavoie, Suzie, Kraftsik, Rudolf, Guidi, Raffaella, Gysin, René, Cuénod, Michel, Do, Kim Q.
Published in Free radical biology & medicine (15.03.2008)
Published in Free radical biology & medicine (15.03.2008)
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Journal Article