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Combined lipidomic and proteomic analysis of isolated human islets exposed to palmitate reveals time-dependent changes in insulin secretion and lipid metabolism
Roomp, Kirsten, Kristinsson, Hjalti, Schvartz, Domitille, Ubhayasekera, Kumari, Sargsyan, Ernest, Manukyan, Levon, Chowdhury, Azazul, Manell, Hannes, Satagopam, Venkata, Groebe, Karlfried, Schneider, Reinhard, Bergquist, Jonas, Sanchez, Jean-Charles, Bergsten, Peter
Published in PloS one (2017)
Published in PloS one (2017)
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Journal Article
Inhibiting the endoplasmic reticulum stress response enhances the effect of doxorubicin by altering the lipid metabolism of liver cancer cells
Kopsida, Maria, Clavero, Ada Lerma, Khaled, Jaafar, Balgoma, David, Luna-Marco, Clara, Chowdhury, Azazul, Nyman, Sofi Sennefelt, Rorsman, Fredrik, Ebeling Barbier, Charlotte, Bergsten, Peter, Lennernäs, Hans, Hedeland, Mikael, Heindryckx, Femke
Published in Molecular metabolism (Germany) (01.01.2024)
Published in Molecular metabolism (Germany) (01.01.2024)
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Journal Article
Identification of a small molecule targeting EPLIN as a novel strategy for the treatment of pediatric neuroblastoma and medulloblastoma
Lindell, Emma, Guo, Jing, Zhao, Miao, Rameika, Natallia, Lu, Xi, Wacker, Tabea, Zhong, Lei, Bergström, Tobias, Svanberg, Sara, Chowdhury, Azazul I., Bergsten, Peter, Chen, Xingqi, Bexell, Daniel, Swartling, Fredrik J., Sjöblom, Tobias, Zhang, Xiaonan
Published in Cell death & disease (23.07.2025)
Published in Cell death & disease (23.07.2025)
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Journal Article
Palmitate-Induced Insulin Hypersecretion and Later Secretory Decline Associated with Changes in Protein Expression Patterns in Human Pancreatic Islets
Groebe, Karlfried, Cen, Jing, Schvartz, Domitille, Sargsyan, Ernest, Chowdhury, Azazul, Roomp, Kirsten, Schneider, Reinhard, Alderborn, Anders, Sanchez, Jean-Charles, Bergsten, Peter
Published in Journal of proteome research (02.11.2018)
Published in Journal of proteome research (02.11.2018)
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Journal Article
Adolescents with obesity treated with exenatide maintain endogenous GLP-1, reduce DPP-4, and improve glycemic control
Stenlid, Rasmus, Cerenius, Sara Y., Wen, Quan, Aydin, Banu Küçükemre, Manell, Hannes, Chowdhury, Azazul, Kristinsson, Hjalti, Ciba, Iris, Gjessing, Erik S., Mörwald, Katharina, Gomahr, Julian, Heu, Verena, Weghuber, Daniel, Forslund, Anders, Bergsten, Peter
Published in Frontiers in endocrinology (Lausanne) (2023)
Published in Frontiers in endocrinology (Lausanne) (2023)
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Journal Article
Iron Chelator VLX600 Inhibits Mitochondrial Respiration and Promotes Sensitization of Neuroblastoma Cells in Nutrition-Restricted Conditions
Jakobsson, Amanda Westergren, Kundu, Snehangshu, Guo, Jing, Chowdhury, Azazul, Zhao, Miao, Lindell, Emma, Bergsten, Peter, Swartling, Fredrik J., Sjöblom, Tobias, Zhang, Xiaonan
Published in Cancers (30.06.2022)
Published in Cancers (30.06.2022)
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Journal Article
Low Fasting Concentrations of Glucagon in Patients with Very Long-Chain Acyl-CoA Dehydrogenase Deficiency
Stenlid, Rasmus, Manell, Hannes, Seth, Rikard, Cerenius, Sara Y., Chowdhury, Azazul, Roa Cortés, Camilla, Nyqvist, Isabelle, Lundqvist, Thomas, Halldin, Maria, Bergsten, Peter
Published in Metabolites (22.06.2023)
Published in Metabolites (22.06.2023)
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Journal Article
Impaired HMG-CoA Reductase Activity Caused by Genetic Variants or Statin Exposure: Impact on Human Adipose Tissue, β-Cells and Metabolome
Sarsenbayeva, Assel, Jui, Bipasha Nandi, Fanni, Giovanni, Barbosa, Pedro, Ahmed, Fozia, Kristófi, Robin, Cen, Jing, Chowdhury, Azazul, Skrtic, Stanko, Bergsten, Peter, Fall, Tove, Eriksson, Jan W., Pereira, Maria J.
Published in Metabolites (25.08.2021)
Published in Metabolites (25.08.2021)
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Journal Article
Metformin restores prohormone processing enzymes and normalizes aberrations in secretion of proinsulin and insulin in palmitate‐exposed human islets
Wen, Quan, Chowdhury, Azazul Islam, Aydin, Banu, Shekha, Mudhir, Stenlid, Rasmus, Forslund, Anders, Bergsten, Peter
Published in Diabetes, obesity & metabolism (01.12.2023)
Published in Diabetes, obesity & metabolism (01.12.2023)
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Journal Article
Inhibition of the Na+-glucose transporter SGLT2 reduces glucose uptake and IFNγ release from activated human CD4+ T cells
Jin, Zhe, Hammoud, Hayma, Bhandage, Amol K., Koreli, Stasini, Chowdhury, Azazul Islam, Bergsten, Peter, Birnir, Bryndis
Published in Frontiers in immunology (2025)
Published in Frontiers in immunology (2025)
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Journal Article
Signaling in Insulin-Secreting MIN6 Pseudoislets and Monolayer Cells
Chowdhury, Azazul, Satagopam, Venkata P, Manukyan, Levon, Artemenko, Konstantin A, Fung, Yi Man Eva, Schneider, Reinhard, Bergquist, Jonas, Bergsten, Peter
Published in Journal of proteome research (06.12.2013)
Published in Journal of proteome research (06.12.2013)
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Journal Article
Altered mitochondrial metabolism in peripheral blood cells from patients with inborn errors of β‐oxidation
Stenlid, Rasmus, Olsson, David, Cen, Jing, Manell, Hannes, Haglind, Charlotte, Chowdhury, Azazul Islam, Bergsten, Peter, Nordenström, Anna, Halldin, Maria
Published in Clinical and translational science (01.01.2022)
Published in Clinical and translational science (01.01.2022)
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Journal Article
Metformin Can Attenuate Beta-Cell Hypersecretion—Implications for Treatment of Children with Obesity
Wen, Quan, Stenlid, Rasmus, Chowdhury, Azazul Islam, Ciba, Iris, Aydin, Banu, Cerenius, Sara Y., Manell, Hannes, Forslund, Anders, Bergsten, Peter
Published in Metabolites (01.08.2023)
Published in Metabolites (01.08.2023)
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Journal Article
Initial hyperinsulinemia and subsequent β-cell dysfunction is associated with elevated palmitate levels
Staaf, Johan, Ubhayasekera, Sarojini J.K.A., Sargsyan, Ernest, Chowdhury, Azazul, Kristinsson, Hjalti, Manell, Hannes, Bergquist, Jonas, Forslund, Anders, Bergsten, Peter
Published in Pediatric research (01.08.2016)
Published in Pediatric research (01.08.2016)
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Journal Article
Role of PIAS1 in palmitate mediated beta cell dysfunction
Chowdhury, Azazul Islam, Hörnaeus, Katarina, Bergquist, Jonas, Bergsten, Peter
Published in Diabetologia (2015)
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Published in Diabetologia (2015)
Journal Article
Biomarker screening in children and adolescents reveals that CUB domain-containing protein 1 is associated with obesity and that hepatocyte growth factor is associated with weight gain
Manell, Hannes, Shen, Qiujin, Chowdhury, Azazul, Roomp, Kirsten, Ciba, Iris, Weghuber, Daniel, Kamali-Moghaddam, Masood, Bergsten, Peter, Forslund, Anders
Published in Obesity medicine (01.05.2023)
Published in Obesity medicine (01.05.2023)
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Journal Article
Functional differences between aggregated and dispersed insulin-producing cells
Chowdhury, A., Dyachok, O., Tengholm, A., Sandler, S., Bergsten, P.
Published in Diabetologia (01.07.2013)
Published in Diabetologia (01.07.2013)
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Journal Article
GABA-mediated inhibition of human CD4+ T cell functions is enhanced by insulin but impaired by high glucose levels
Jin, Zhe, Hammoud, Hayma, Bhandage, Amol Keshavasa, Korol, Sergiy Vasylyovych, Trujeque-Ramos, Olivia, Koreli, Stasini, Gong, Zhitao, Chowdhury, Azasul Islam, Sandbaumhüter, Friederike Andrea, Jansson, Erik Tomas, Lindsay, Robin Sean, Christoffersson, Gustaf, Andrén, Per Erik, Carlsson, Per-Ola, Bergsten, Peter, Kamali-Moghaddam, Masood, Birnir, Bryndis
Published in EBioMedicine (01.07.2024)
Published in EBioMedicine (01.07.2024)
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Journal Article
Initial hyperinsulinemia and subsequent [beta]-cell dysfunction is associated with elevated palmitate levels
Staaf, Johan, Ubhayasekera, Sarojini Jka, Sargsyan, Ernest, Chowdhury, Azazul, Kristinsson, Hjalti, Manell, Hannes, Bergquist, Jonas, slund, Anders, Bergsten, Peter
Published in Pediatric research (01.08.2016)
Published in Pediatric research (01.08.2016)
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Journal Article