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PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate

by Chessa, Tamara A M, Jung, Piotr, Anwar, Arqum, Suire, Sabine, Anderson, Karen E, Barneda, David, Kielkowska, Anna, Sadiq, Barzan A, Lai, Ieng Wai, Felisbino, Sergio, Turnham, Daniel J, Pearson, Helen B, Phillips, Wayne A, Sasaki, Junko, Sasaki, Takehiko, Oxley, David, Spensberger, Dominik, Segonds-Pichon, Anne, Wilson, Michael, Walker, Simon, Okkenhaug, Hanneke, Cosulich, Sabina, Hawkins, Phillip T, Stephens, Len R
Published in Molecular cell (17.08.2023)

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Journal Article

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PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K

by Malek, Mouhannad, Kielkowska, Anna, Chessa, Tamara, Anderson, Karen E., Barneda, David, Pir, Pınar, Nakanishi, Hiroki, Eguchi, Satoshi, Koizumi, Atsushi, Sasaki, Junko, Juvin, Véronique, Kiselev, Vladimir Y., Niewczas, Izabella, Gray, Alexander, Valayer, Alexandre, Spensberger, Dominik, Imbert, Marine, Felisbino, Sergio, Habuchi, Tomonori, Beinke, Soren, Cosulich, Sabina, Le Novère, Nicolas, Sasaki, Takehiko, Clark, Jonathan, Hawkins, Phillip T., Stephens, Len R.
Published in Molecular cell (02.11.2017)

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PtdIns3P and Rac direct the assembly of the NADPH oxidase on a novel, pre-phagosomal compartment during FcR-mediated phagocytosis in primary mouse neutrophils

by Anderson, Karen E., Chessa, Tamara A.M., Davidson, Keith, Henderson, Robert B., Walker, Simon, Tolmachova, Tanya, Grys, Katarzyna, Rausch, Oliver, Seabra, Miguel C., Tybulewicz, Victor L.J., Stephens, Len R., Hawkins, Phillip T.
Published in Blood (02.12.2010)

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CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks

by Anderson, Karen E., Boyle, Keith B., Davidson, Keith, Chessa, Tamara A.M., Kulkarni, Suhasini, Jarvis, Gavin E., Sindrilaru, Anca, Scharffetter-Kochanek, Karin, Rausch, Oliver, Stephens, Len R., Hawkins, Phillip T.
Published in Blood (15.12.2008)

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PI3Kδ Forms Distinct Multiprotein Complexes at the TCR Signalosome in Naïve and Differentiated CD4+ T Cells

by Luff, Daisy H., Wojdyla, Katarzyna, Oxley, David, Chessa, Tamara, Hudson, Kevin, Hawkins, Phillip T., Stephens, Len R., Barry, Simon T., Okkenhaug, Klaus
Published in Frontiers in immunology (08.03.2021)

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Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells

by Koohy, Hashem, Bolland, Daniel J., Matheson, Louise S., Schoenfelder, Stefan, Stellato, Claudia, Dimond, Andrew, Várnai, Csilla, Chovanec, Peter, Chessa, Tamara, Denizot, Jeremy, Manzano Garcia, Raquel, Wingett, Steven W., Freire-Pritchett, Paula, Nagano, Takashi, Hawkins, Phillip, Stephens, Len, Elderkin, Sarah, Spivakov, Mikhail, Fraser, Peter, Corcoran, Anne E., Varga-Weisz, Patrick D.
Published in Genome Biology (05.09.2018)

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Class (I) Phosphoinositide 3-Kinases in the Tumor Microenvironment

by Gyori, David, Chessa, Tamara, Hawkins, Phillip, Stephens, Len
Published in Cancers (04.03.2017)

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Journal Article

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Overexpression of PPK-1, the Caenorhabditis elegans Type I PIP kinase, inhibits growth cone collapse in the developing nervous system and causes axonal degeneration in adults

by Weinkove, David, Bastiani, Michael, Chessa, Tamara A.M., Joshi, Deepa, Hauth, Linda, Cooke, Frank T., Divecha, Nullin, Schuske, Kim
Published in Developmental biology (2008)

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Phosphorylation of threonine 154 in p40phox is an important physiological signal for activation of the neutrophil NADPH oxidase

by Chessa, Tamara A.M., Anderson, Karen E., Hu, Yanhua, Xu, Qingbo, Rausch, Oliver, Stephens, Len R., Hawkins, Phillip T.
Published in Blood (23.12.2010)

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Journal Article

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Signaling via Class IA Phosphoinositide 3-Kinases (PI3K) in Human, Breast-Derived Cell Lines

by Juvin, Veronique, Malek, Mouhannad, Anderson, Karen E., Dion, Carine, Chessa, Tamara, Lecureuil, Charlotte, Ferguson, G. John, Cosulich, Sabina, Hawkins, Phillip T., Stephens, Len R.
Published in PloS one (04.10.2013)

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Journal Article

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PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate

by Chessa, Tamara A.M., Jung, Piotr, Anwar, Arqum, Suire, Sabine, Anderson, Karen E., Barneda, David, Kielkowska, Anna, Sadiq, Barzan A., Lai, Ieng Wai, Felisbino, Sergio, Turnham, Daniel J., Pearson, Helen B., Phillips, Wayne A., Sasaki, Junko, Sasaki, Takehiko, Oxley, David, Spensberger, Dominik, Segonds-Pichon, Anne, Wilson, Michael, Walker, Simon, Okkenhaug, Hanneke, Cosulich, Sabina, Hawkins, Phillip T., Stephens, Len R.
Published in Molecular cell (01.08.2023)

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Journal Article

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Signaling via Class IA Phosphoinositide 3-Kinases

by Juvin, Veronique, Malek, Mouhannad, Anderson, Karen E, Dion, Carine, Chessa, Tamara, Lecureuil, Charlotte, Ferguson, G. John, Cosulich, Sabina, Hawkins, Phillip T, Stephens, Len R
Published in PloS one (04.10.2013)

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Journal Article

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Localizing the lipid products of PI3Kγ in neutrophils

by Norton, Laura, Lindsay, Yvonne, Deladeriere, Arnaud, Chessa, Tamara, Guillou, Hervé, Suire, Sabine, Lucocq, John, Walker, Simon, Andrews, Simon, Segonds-Pichon, Anne, Rausch, Oliver, Finan, Peter, Sasaki, Takehiko, Du, Cheng-Jin, Bretschneider, Till, Ferguson, G. John, Hawkins, Phillip T., Stephens, Len
Published in Advances in biological regulation (01.01.2016)

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Journal Article

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PTEN Regulates PI(3,4)P 2 Signaling Downstream of Class I PI3K

by Malek, Mouhannad, Kielkowska, Anna, Chessa, Tamara, Anderson, Karen E, Barneda, David, Pir, Pınar, Nakanishi, Hiroki, Eguchi, Satoshi, Koizumi, Atsushi, Sasaki, Junko, Juvin, Véronique, Kiselev, Vladimir Y, Niewczas, Izabella, Gray, Alexander, Valayer, Alexandre, Spensberger, Dominik, Imbert, Marine, Felisbino, Sergio, Habuchi, Tomonori, Beinke, Soren, Cosulich, Sabina, Le Novère, Nicolas, Sasaki, Takehiko, Clark, Jonathan, Hawkins, Phillip T, Stephens, Len R
Published in Molecular cell (02.11.2017)

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Journal Article

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Overexpression of PPK-1, the C. elegans Type 1 PIP kinase, inhibits growth cone collapse in the developing nervous system and causes axonal degeneration in adults

by Weinkove, David, Bastiani, Michael, Chessa, Tamara A. M., Joshi, Deepa, Hauth, Linda, Cooke, Frank T., Divecha, Nullin, Schuske, Kim
Published in Developmental biology (26.11.2007)

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Journal Article

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TREATMENT OF CANCER BY MODULATION OF PLEKSH1

by CHESSA, Tamara, HAWKINS, Phillip Thomas, STEPHENS, Leonard Robert
Year of Publication 26.09.2024

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Patent

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CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks. Commentary

by KENNEDY, Adam D, DELEO, Frank R, RAUSCH, Oliver, STEPHENS, Len R, HAWKINS, Phillip T, ANDERSON, Karen E, BOYLE, Keith B, DAVIDSON, Keith, CHESSA, Tamara A. M, KULKARNI, Suhasini, JARVIS, Gavin E, SINDRILARU, Anca, SCHARFFETTER-KOCHANEK, Karin
Published in Blood (2008)

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Journal Article

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PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate

by Chessa, Tamara, Jung, Piotr, Suire, Sabine, Anwar, Arqum, Anderson, Karen E., Barneda, David, Kielkowska, Anna, Sadiq, Barzan A., Felisbino, Sergio, Oxley, David, Spensberger, Dominik, Segonds-Pichon, Anne, Wilson, Michael, Walker, Simon, Okkenhaug, Hanneke, Cosulich, Sabina, Hawkins, Phillip T., Stephens, Len R.
Published in bioRxiv (18.05.2023)

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