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Clearance of beta-amyloid is facilitated by apolipoprotein E and circulating high-density lipoproteins in bioengineered human vessels
Robert, Jerome, Button, Emily B, Yuen, Brian, Gilmour, Megan, Kang, Kevin, Bahrabadi, Arvin, Stukas, Sophie, Zhao, Wenchen, Kulic, Iva, Wellington, Cheryl L
Published in eLife (10.10.2017)
Published in eLife (10.10.2017)
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Journal Article
ApoA-I deficiency increases cortical amyloid deposition, cerebral amyloid angiopathy, cortical and hippocampal astrogliosis, and amyloid-associated astrocyte reactivity in APP/PS1 mice
Button, Emily B., Boyce, Guilaine K., Wilkinson, Anna, Stukas, Sophie, Hayat, Arooj, Fan, Jianjia, Wadsworth, Brennan J., Robert, Jerome, Martens, Kris M., Wellington, Cheryl L.
Published in Alzheimer's research & therapy (13.05.2019)
Published in Alzheimer's research & therapy (13.05.2019)
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Journal Article
CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice
Cheng, Wai Hang, Martens, Kris M., Bashir, Asma, Cheung, Honor, Stukas, Sophie, Gibbs, Ebrima, Namjoshi, Dhananjay R., Button, Emily B., Wilkinson, Anna, Barron, Carlos J., Cashman, Neil R., Cripton, Peter A., Wellington, Cheryl L.
Published in Alzheimer's research & therapy (12.01.2019)
Published in Alzheimer's research & therapy (12.01.2019)
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Journal Article
Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E
Robert, Jerome, Button, Emily B., Martin, Emma M., McAlary, Luke, Gidden, Zoe, Gilmour, Megan, Boyce, Guilaine, Caffrey, Tara M., Agbay, Andrew, Clark, Amanda, Silverman, Judith M., Cashman, Neil R., Wellington, Cheryl L.
Published in Molecular neurodegeneration (25.03.2020)
Published in Molecular neurodegeneration (25.03.2020)
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Journal Article
Microglial Cell Activation Increases Saturated and Decreases Monounsaturated Fatty Acid Content, but Both Lipid Species are Proinflammatory
Button, Emily B., Mitchell, Andrew S., Domingos, Marcia M., Chung, Jessica H.-J., Bradley, Ryan M., Hashemi, Ashkan, Marvyn, Phillip M., Patterson, Ashley C., Stark, Ken D., Quadrilatero, Joe, Duncan, Robin E.
Published in Lipids (01.04.2014)
Published in Lipids (01.04.2014)
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Journal Article
Development of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury
Button, Emily B., Cheng, Wai Hang, Barron, Carlos, Cheung, Honor, Bashir, Asma, Cooper, Jennifer, Gill, Jasmine, Stukas, Sophie, Baron, David C., Robert, Jerome, Rowe, Elyn M., Cripton, Peter A., Wellington, Cheryl L.
Published in Alzheimer's research & therapy (07.03.2021)
Published in Alzheimer's research & therapy (07.03.2021)
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Journal Article
An in vitro bioengineered model of the human arterial neurovascular unit to study neurodegenerative diseases
Robert, Jerome, Weilinger, Nicholas L., Cao, Li-Ping, Cataldi, Stefano, Button, Emily B., Stukas, Sophie, Martin, Emma M., Seibler, Philip, Gilmour, Megan, Caffrey, Tara M., Rowe, Elyn M., Fan, Jianjia, MacVicar, Brian, Farrer, Matthew J., Wellington, Cheryl L.
Published in Molecular neurodegeneration (19.11.2020)
Published in Molecular neurodegeneration (19.11.2020)
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Journal Article
Increased severity of the CHIMERA model induces acute vascular injury, sub-acute deficits in memory recall, and chronic white matter gliosis
Bashir, Asma, Abebe, Zelalem A., McInnes, Kurt A., Button, Emily B., Tatarnikov, Igor, Cheng, Wai Hang, Haber, Margalit, Wilkinson, Anna, Barron, Carlos, Diaz-Arrastia, Ramon, Stukas, Sophie, Cripton, Peter A., Wellington, Cheryl L.
Published in Experimental neurology (01.02.2020)
Published in Experimental neurology (01.02.2020)
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Journal Article
Age at injury and genotype modify acute inflammatory and neurofilament-light responses to mild CHIMERA traumatic brain injury in wild-type and APP/PS1 mice
Cheng, Wai Hang, Stukas, Sophie, Martens, Kris M., Namjoshi, Dhananjay R., Button, Emily B., Wilkinson, Anna, Bashir, Asma, Robert, Jerome, Cripton, Peter A., Wellington, Cheryl L.
Published in Experimental neurology (01.03.2018)
Published in Experimental neurology (01.03.2018)
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Journal Article
Vasoprotective Functions of High-Density Lipoproteins Relevant to Alzheimer’s Disease Are Partially Conserved in Apolipoprotein B-Depleted Plasma
Button, Emily B., Gilmour, Megan, Cheema, Harleen K., Martin, Emma M., Agbay, Andrew, Robert, Jérôme, Wellington, Cheryl L.
Published in International journal of molecular sciences (22.01.2019)
Published in International journal of molecular sciences (22.01.2019)
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Journal Article
High-density lipoproteins suppress Aβ-induced PBMC adhesion to human endothelial cells in bioengineered vessels and in monoculture
Robert, Jérôme, Button, Emily B., Stukas, Sophie, Boyce, Guilaine K., Gibbs, Ebrima, Cowan, Catherine M., Gilmour, Megan, Cheng, Wai Hang, Soo, Sonja K., Yuen, Brian, Bahrabadi, Arvin, Kang, Kevin, Kulic, Iva, Francis, Gordon, Cashman, Neil, Wellington, Cheryl L.
Published in Molecular neurodegeneration (22.08.2017)
Published in Molecular neurodegeneration (22.08.2017)
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Journal Article
The effects of peripheral lipoprotein metabolism on cerebrovascular inflammation in APP/PS1 mice
Button, Emily B., Boyce, Guilaine K., Wilkinson, Anna, Stukas, Sophie K., Hayat, Arooj, Cheng, Wai Hang, Wadsworth, Brennan J., Fan, Jianjia, Robert, Jerome, Martens, Kris M., Wellington, Cheryl L.
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Cerebrovascular amyloid angiopathy in bioengineered vessels is reduced by high‐density lipoprotein particles enriched in apolipoprotein E
Robert, Jerome, Button, Emily B., Martin, Emma, McAlary, Luke, Gidden, Zoe, Gilmore, Megan, Boyce, Guilaine K., Caffrey, Tara M., Agbay, Andrew, Clark, Amanda, Silverman, Judith M, Cashman, Neil R., Wellington, Cheryl L.
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Cerebrovascular amyloid angiopathy in bioengineered vessels is reduced by high‐density lipoprotein particles enriched in apolipoprotein E: Development of new models and analysis methods/amyloid/Abeta
Robert, Jerome, Button, Emily B., Martin, Emma, McAlary, Luke, Gidden, Zoe, Gilmore, Megan, Boyce, Guilaine K., Caffrey, Tara M., Agbay, Andrew, Clark, Amanda, Silverman, Judith M, Cashman, Neil R., Wellington, Cheryl L.
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
The effects of peripheral lipoprotein metabolism on cerebrovascular inflammation in APP/PS1 mice: Molecular and cell biology/vascular factors
Button, Emily B., Boyce, Guilaine K., Wilkinson, Anna, Stukas, Sophie K., Hayat, Arooj, Cheng, Wai Hang, Wadsworth, Brennan J., Fan, Jianjia, Robert, Jerome, Martens, Kris M., Wellington, Cheryl L.
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
APOA-I DEFICIENCY INCREASES CORTICAL AMYLOID DEPOSITION, CEREBRAL AMYLOID ANGIOPATHY, CORTICAL AND HIPPOCAMPAL ASTROGLIOSIS AND AMYLOID-ASSOCIATED ASTROCYTE REACTIVITY IN APP/PS1 MICE
Button, Emily B., Boyce, Guilaine K., Wilkinson, Anna, Stukas, Sophie K., Robert, Jerome, Button, Emily B., Fan, Jianjia, Martens, Kris M., Wellington, Cheryl L.
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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Journal Article
P4‐164: APOA‐I DEFICIENCY INCREASES CORTICAL AMYLOID DEPOSITION, CEREBRAL AMYLOID ANGIOPATHY, CORTICAL AND HIPPOCAMPAL ASTROGLIOSIS AND AMYLOID‐ASSOCIATED ASTROCYTE REACTIVITY IN APP/PS1 MICE
Button, Emily B., Boyce, Guilaine K., Wilkinson, Anna, Stukas, Sophie K., Robert, Jerome, Button, Emily B., Fan, Jianjia, Martens, Kris M., Wellington, Cheryl L.
Published in Alzheimer's & dementia (01.07.2019)
Published in Alzheimer's & dementia (01.07.2019)
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Journal Article
[O2–04–01]: CLEARANCE OF BETA‐AMYLOID IS FACILITATED BY APOLIPOPROTEIN E AND CIRCULATING HIGH‐DENSITY LIPOPROTEINS IN BIOENGINEERED HUMAN VESSELS
Robert, Jerome, Button, Emily B., Soo, Sonja, Yuen, Brian, Kang, Kevin, Bahrabadi, Arvin, Stukas, Sophie, Zhao, Wenchen, Wellington, Cheryl
Published in Alzheimer's & dementia (01.07.2017)
Published in Alzheimer's & dementia (01.07.2017)
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Journal Article