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Phase 1 clinical trial of losmapimod in facioscapulohumeral dystrophy: Safety, tolerability, pharmacokinetics, and target engagement
Mellion, Michelle L., Ronco, Lucienne, Berends, Cecile L., Pagan, Lisa, Brooks, Sander, Esdonk, Michiel J., Brummelen, Emilie M. J., Odueyungbo, Adefowope, Thompson, Lorin A., Hage, Michelle, Badrising, Umesh A., Raines, Shane, Tracewell, William G., Engelen, Baziel, Cadavid, Diego, Groeneveld, Geert J.
Published in British journal of clinical pharmacology (01.12.2021)
Published in British journal of clinical pharmacology (01.12.2021)
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Journal Article
Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans
Salvadore, Giacomo, Bonaventure, Pascal, Shekhar, Anantha, Johnson, Philip L., Lord, Brian, Shireman, Brock T., Lebold, Terry P., Nepomuceno, Diane, Dugovic, Christine, Brooks, Sander, Zuiker, Rob, Bleys, Cathy, Tatikola, Kanaka, Remmerie, Bart, Jacobs, Gabriel E., Schruers, Koen, Moyer, John, Nash, Abigail, Van Nueten, Luc G. M., Drevets, Wayne C.
Published in Translational psychiatry (07.09.2020)
Published in Translational psychiatry (07.09.2020)
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Journal Article
F13. Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Properties of the Selective Orexin-1 Receptor Antagonist JNJ-61393215: Results From the First-In-Human and Multiple Ascending Dose Studies
Salvadore, Giacomo, Brooks, Sander, Cathy, Bleys, Moyer, John, Shireman, Brock, Bonaventure, Pascal, Remmerie, Bart, Tatikola, Kanaka, Jacobs, Gabriel, van Nueten, Luc, Drevets, Wayne
Published in Biological psychiatry (1969) (15.05.2019)
Published in Biological psychiatry (1969) (15.05.2019)
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Journal Article
Light Fractionation Significantly Increases the Efficacy of Photodynamic Therapy Using BF-200 ALA in Normal Mouse Skin
de Bruijn, Henriëtte S., Brooks, Sander, van der Ploeg-van den Heuvel, Angélique, ten Hagen, Timo L. M., de Haas, Ellen R. M., Robinson, Dominic J.
Published in PloS one (12.02.2016)
Published in PloS one (12.02.2016)
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Journal Article
Multiple-dose clinical pharmacology of ACT-541468, a novel dual orexin receptor antagonist, following repeated-dose morning and evening administration
Muehlan, Clemens, Brooks, Sander, Zuiker, Rob, van Gerven, Joop, Dingemanse, Jasper
Published in European neuropsychopharmacology (01.07.2019)
Published in European neuropsychopharmacology (01.07.2019)
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Journal Article
Driving Performance after Bedtime Administration of Daridorexant, Assessed in a Sensitive Simulator
Muehlan, Clemens, Brooks, Sander, Vaillant, Cedric, Meinel, Michael, Jacobs, Gabriël E., Zuiker, Rob G., Dingemanse, Jasper
Published in Clinical pharmacology and therapeutics (01.06.2022)
Published in Clinical pharmacology and therapeutics (01.06.2022)
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Journal Article
Pharmacological Interactions between the Dual Orexin Receptor Antagonist Daridorexant and Ethanol in a Double-Blind, Randomized, Placebo-Controlled, Double-Dummy, Four-Way Crossover Phase I Study in Healthy Subjects
Berger, Benjamin, Brooks, Sander, Zuiker, Rob, Richard, Muriel, Muehlan, Clemens, Dingemanse, Jasper
Published in CNS drugs (01.12.2020)
Published in CNS drugs (01.12.2020)
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Journal Article
0377 Clinical Pharmacology Of The Dual Orexin Receptor Antagonist Act-541468 In Elderly Subjects
Muehlan, Clemens, Zuiker, Rob, Brooks, Sander, Gerven, Joop van, Dingemanse, Jasper
Published in Sleep (New York, N.Y.) (13.04.2019)
Published in Sleep (New York, N.Y.) (13.04.2019)
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Journal Article
Sources of variability in the quantification of tissue optical properties by multidiameter single-fiber reflectance and fluorescence spectroscopy
Brooks, Sander, Hoy, Christopher L, Amelink, Arjen, Robinson, Dominic J, Nijsten, Tamar E
Published in Journal of biomedical optics (01.05.2015)
Published in Journal of biomedical optics (01.05.2015)
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Journal Article
Light Fractionation Significantly Increases the Efficacy of Photodynamic Therapy Using BF-200 ALA in Normal Mouse Skin: e0148850
Bruijn, Henrieette Sde, Brooks, Sander, Heuvel, der Ploeg-vanden, Hagen, L Mten, Haas, R Mde, Robinson, Dominic J
Published in PloS one (01.02.2016)
Published in PloS one (01.02.2016)
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Journal Article
Light fractionation improves the response to BF-200 ALA-PDT in hairless mouse skin
de Bruijn, Henriëtte S., Brooks, Sander, Heuvel, Angèlique van der Ploeg-van den, de Haas, Ellen R.M., Robinson, Dominic J.
Published in Photodiagnosis and photodynamic therapy (01.09.2015)
Published in Photodiagnosis and photodynamic therapy (01.09.2015)
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Journal Article