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Plasma, tumor and tissue pharmacokinetics of Docetaxel delivered via nanoparticles of different sizes and shapes in mice bearing SKOV-3 human ovarian carcinoma xenograft
Chu, Kevin S., Hasan, Warefta, Rawal, Sumit, Walsh, Mark D., Enlow, Elizabeth M., Luft, J. Christopher, Bridges, Arlene S., Kuijer, Jennifer L., Napier, Mary E., Zamboni, William C., DeSimone, Joseph M.
Published in Nanomedicine (01.07.2013)
Published in Nanomedicine (01.07.2013)
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Journal Article
Hepatic Basolateral Efflux Contributes Significantly to Rosuvastatin Disposition II: Characterization of Hepatic Elimination by Basolateral, Biliary, and Metabolic Clearance Pathways in Rat Isolated Perfused Liver
Pfeifer, Nathan D., Bridges, Arlene S., Ferslew, Brian C., Hardwick, Rhiannon N., Brouwer, Kim L.R.
Published in The Journal of pharmacology and experimental therapeutics (01.12.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2013)
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Journal Article
In Vitro Biliary Clearance of Angiotensin II Receptor Blockers and 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase Inhibitors in Sandwich-Cultured Rat Hepatocytes: Comparison with in Vivo Biliary Clearance
Abe, Koji, Bridges, Arlene S., Yue, Wei, Brouwer, Kim L.R.
Published in The Journal of pharmacology and experimental therapeutics (01.09.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2008)
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Journal Article
Breast Cancer Resistance Protein Interacts with Various Compounds in Vitro, but Plays a Minor Role in Substrate Efflux at the Blood-Brain Barrier
Zhao, Rong, Raub, Thomas J., Sawada, Geri A., Kasper, Steven C., Bacon, James A., Bridges, Arlene S., Pollack, Gary M.
Published in Drug metabolism and disposition (01.06.2009)
Published in Drug metabolism and disposition (01.06.2009)
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Journal Article
Evaluation of the Role of Multidrug Resistance-Associated Protein (Mrp) 3 and Mrp4 in Hepatic Basolateral Excretion of Sulfate and Glucuronide Metabolites of Acetaminophen, 4-Methylumbelliferone, and Harmol in Abcc3–/– and Abcc4–/– Mice
Zamek-Gliszczynski, Maciej J., Nezasa, Ken-ichi, Tian, Xianbin, Bridges, Arlene S., Lee, Kun, Belinsky, Martin G., Kruh, Gary D., Brouwer, Kim L.R.
Published in The Journal of pharmacology and experimental therapeutics (01.12.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2006)
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Journal Article
Directing the biological activities of heparan sulfate oligosaccharides using a chemoenzymatic approach
Xu, Yongmei, Wang, Zhen, Liu, Renpeng, Bridges, Arlene S, Huang, Xuefei, Liu, Jian
Published in Glycobiology (Oxford) (01.01.2012)
Published in Glycobiology (Oxford) (01.01.2012)
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Journal Article
Chemotherapy of Second Stage Human African Trypanosomiasis: Comparison between the Parenteral Diamidine DB829 and Its Oral Prodrug DB868 in Vervet Monkeys
Thuita, John K., Wolf, Kristina K., Murilla, Grace A., Bridges, Arlene S., Boykin, David W., Mutuku, James N., Liu, Qiang, Jones, Susan K., Gem, Charles O., Ching, Shelley, Tidwell, Richard R., Wang, Michael Z., Paine, Mary F., Brun, Reto
Published in PLoS neglected tropical diseases (01.02.2015)
Published in PLoS neglected tropical diseases (01.02.2015)
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Journal Article
Fexofenadine Brain Exposure and the Influence of Blood-Brain Barrier P-Glycoprotein After Fexofenadine and Terfenadine Administration
Zhao, Rong, Kalvass, J. Cory, Yanni, Souzan B., Bridges, Arlene S., Pollack, Gary M.
Published in Drug metabolism and disposition (01.03.2009)
Published in Drug metabolism and disposition (01.03.2009)
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Journal Article
Human Enteric Microsomal CYP4F Enzymes O-Demethylate the Antiparasitic Prodrug Pafuramidine
Wang, Michael Zhuo, Wu, Judy Qiju, Bridges, Arlene S., Zeldin, Darryl C., Kornbluth, Sally, Tidwell, Richard R., Hall, James Edwin, Paine, Mary F.
Published in Drug metabolism and disposition (01.11.2007)
Published in Drug metabolism and disposition (01.11.2007)
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Journal Article
CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
Wang, Michael Zhuo, Saulter, Janelle Y., Usuki, Etsuko, Cheung, Yen-Ling, Hall, Michael, Bridges, Arlene S., Loewen, Greg, Parkinson, Oliver T., Stephens, Chad E., Allen, James L., Zeldin, Darryl C., Boykin, David W., Tidwell, Richard R., Parkinson, Andrew, Paine, Mary F., Hall, James Edwin
Published in Drug metabolism and disposition (01.12.2006)
Published in Drug metabolism and disposition (01.12.2006)
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Journal Article
Diphenyl Furans and Aza Analogs: Effects of Structural Modification on In Vitro Activity, DNA Binding, and Accumulation and Distribution in Trypanosomes
Mathis, Amanda M., Bridges, Arlene S., Ismail, Mohamed A., Kumar, Arvind, Francesconi, Iris, Anbazhagan, Mariappan, Hu, Qiyue, Tanious, Farial A., Wenzler, Tanja, Saulter, Janelle, Wilson, W. David, Brun, Reto, Boykin, David W., Tidwell, Richard R., Hall, James Edwin
Published in Antimicrobial Agents and Chemotherapy (01.08.2007)
Published in Antimicrobial Agents and Chemotherapy (01.08.2007)
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Journal Article
Safety, Pharmacokinetic, and Efficacy Studies of Oral DB868 in a First Stage Vervet Monkey Model of Human African Trypanosomiasis
Thuita, John K., Wolf, Kristina K., Murilla, Grace A., Liu, Qiang, Mutuku, James N., Chen, Yao, Bridges, Arlene S., Mdachi, Raymond E., Ismail, Mohamed A., Ching, Shelley, Boykin, David W., Hall, James Edwin, Tidwell, Richard R., Paine, Mary F., Brun, Reto, Wang, Michael Zhuo
Published in PLoS neglected tropical diseases (01.06.2013)
Published in PLoS neglected tropical diseases (01.06.2013)
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Journal Article
Multidrug Resistance-Associated Protein 2 Is Primarily Responsible for the Biliary Excretion of Fexofenadine in Mice
Tian, Xianbin, Zamek-Gliszczynski, Maciej J., Li, Jun, Bridges, Arlene S., Nezasa, Ken-ichi, Patel, Nita J., Raub, Thomas J., Brouwer, Kim L.R.
Published in Drug metabolism and disposition (01.01.2008)
Published in Drug metabolism and disposition (01.01.2008)
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Journal Article
A gel-free MS-based quantitative proteomic approach accurately measures cytochrome P450 protein concentrations in human liver microsomes
Wang, Michael Zhuo, Wu, Judy Qiju, Dennison, Jennifer B., Bridges, Arlene S., Hall, Stephen D., Kornbluth, Sally, Tidwell, Richard R., Smith, Philip C., Voyksner, Robert D., Paine, Mary F., Hall, James Edwin
Published in Proteomics (Weinheim) (01.10.2008)
Published in Proteomics (Weinheim) (01.10.2008)
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Journal Article
Sex-Dependent Disposition of Acetaminophen Sulfate and Glucuronide in the in Situ Perfused Mouse Liver
Lee, Jin Kyung, Abe, Koji, Bridges, Arlene S., Patel, Nita J., Raub, Thomas J., Pollack, Gary M., Brouwer, Kim L.R.
Published in Drug metabolism and disposition (01.09.2009)
Published in Drug metabolism and disposition (01.09.2009)
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Journal Article
Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons
Huang, Hsien-Sung, Allen, John A., Mabb, Angela M., King, Ian F., Miriyala, Jayalakshmi, Taylor-Blake, Bonnie, Sciaky, Noah, Dutton, J. Walter, Lee, Hyeong-Min, Chen, Xin, Jin, Jian, Bridges, Arlene S., Zylka, Mark J., Roth, Bryan L., Philpot, Benjamin D.
Published in Nature (London) (21.12.2011)
Published in Nature (London) (21.12.2011)
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Journal Article
Chemoenzymatic Design of Heparan Sulfate Oligosaccharides
Liu, Renpeng, Xu, Yongmei, Chen, Miao, Weïwer, Michel, Zhou, Xianxuan, Bridges, Arlene S., DeAngelis, Paul L., Zhang, Qisheng, Linhardt, Robert J., Liu, Jian
Published in The Journal of biological chemistry (29.10.2010)
Published in The Journal of biological chemistry (29.10.2010)
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Journal Article