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Serum protein binding of 25 antiepileptic drugs in a routine clinical setting: A comparison of free non–protein‐bound concentrations
Patsalos, Philip N., Zugman, Miguel, Lake, Charlotte, James, Anthony, Ratnaraj, Neville, Sander, Josemir W.
Published in Epilepsia (Copenhagen) (01.07.2017)
Published in Epilepsia (Copenhagen) (01.07.2017)
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Journal Article
A Placebo- and Midazolam-Controlled Phase I Single Ascending-Dose Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Remimazolam (CNS 7056): Part I. Safety, Efficacy, and Basic Pharmacokinetics
Antonik, Laurie J., Goldwater, D. Ronald, Kilpatrick, Gavin J., Tilbrook, Gary S., Borkett, Keith M.
Published in Anesthesia and analgesia (01.08.2012)
Published in Anesthesia and analgesia (01.08.2012)
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Journal Article
A Placebo- and Midazolam-Controlled Phase I Single Ascending-Dose Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Remimazolam (CNS 7056): Part II. Population Pharmacokinetic and Pharmacodynamic Modeling and Simulation
Wiltshire, Hugh R., Kilpatrick, Gavin J., Tilbrook, Gary S., Borkett, Keith M.
Published in Anesthesia and analgesia (01.08.2012)
Published in Anesthesia and analgesia (01.08.2012)
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Journal Article
Multifaceted Bioanalytical Methods for the Comprehensive Pharmacokinetic and Catabolic Assessment of MEDI3726, an Anti-Prostate-Specific Membrane Antigen Pyrrolobenzodiazepine Antibody–Drug Conjugate
Huang, Yue, Del Nagro, Christopher J, Balic, Kemal, Ismaiel, Omnia A, Ma, Eric, Faria, Morse, Wheeler, Aaron M, Yuan, Moucun, Waldron, Michael P, Peay, Marlking G, Cortes, Diego F, Roskos, Lorin, Liang, Meina, Rosenbaum, Anton I
Published in Analytical chemistry (Washington) (18.08.2020)
Published in Analytical chemistry (Washington) (18.08.2020)
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Journal Article
Test-retest reproducibility of quantitative binding measures of [ 11 C]Ro15-4513, a PET ligand for GABA A receptors containing alpha5 subunits
McGinnity, Colm J., Riaño Barros, Daniela A., Rosso, Lula, Veronese, Mattia, Rizzo, Gaia, Bertoldo, Alessandra, Hinz, Rainer, Turkheimer, Federico E., Koepp, Matthias J., Hammers, Alexander
Published in NeuroImage (Orlando, Fla.) (15.05.2017)
Published in NeuroImage (Orlando, Fla.) (15.05.2017)
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Journal Article
A population pharmacodynamic Markov mixed‐effects model for determining remimazolam‐induced sedation when co‐administered with fentanyl in procedural sedation
Zhou, Jie, Curd, Laura, Lohmer, Lauren R. L., Delpratt, Natalie, Ossig, Joachim, Schippers, Frank, Stoehr, Thomas, Schmith, Virginia D.
Published in Clinical and translational science (01.07.2021)
Published in Clinical and translational science (01.07.2021)
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Journal Article
Application of a Systems Approach to the Bottom-Up Assessment of Pharmacokinetics in Obese Patients: Expected Variations in Clearance
Ghobadi, Cyrus, Johnson, Trevor N., Aarabi, Mohsen, Almond, Lisa M., Allabi, Aurel Constant, Rowland-Yeo, Karen, Jamei, Masoud, Rostami-Hodjegan, Amin
Published in Clinical pharmacokinetics (01.12.2011)
Published in Clinical pharmacokinetics (01.12.2011)
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Journal Article
Impact of Increased Gastric pH on the Pharmacokinetics of Evacetrapib in Healthy Subjects
Small, David S., Royalty, Jane, Cannady, Ellen A., Hale, Christine, Wang, Ming‐Dauh, Downs, Delyn, Suico, Jeffrey G.
Published in Pharmacotherapy (01.07.2016)
Published in Pharmacotherapy (01.07.2016)
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Journal Article
Remimazolam Has Low Oral Bioavailability and No Potential for Misuse in Drug-Facilitated Sexual Assaults, with or Without Alcohol: Results from Two Randomised Clinical Trials
Pesic, Marija, Stöhr, Thomas, Ossig, Joachim, Borkett, Keith, Donsbach, Martin, Dao, Van-Anh, Webster, Lynn, Schippers, Frank
Published in Drugs in R&D (01.09.2020)
Published in Drugs in R&D (01.09.2020)
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Journal Article
Absolute bioavailability of evacetrapib in healthy subjects determined by simultaneous administration of oral evacetrapib and intravenous [13C8]-evacetrapib as a tracer
Cannady, Ellen A., Aburub, Aktham, Ward, Chris, Hinds, Chris, Czeskis, Boris, Ruterbories, Kenneth, Suico, Jeffrey G., Royalty, Jane, Ortega, Demetrio, Pack, Brian W., Begum, Syeda L., Annes, William F., Lin, Qun, Small, David S.
Published in Journal of labelled compounds & radiopharmaceuticals (30.05.2016)
Published in Journal of labelled compounds & radiopharmaceuticals (30.05.2016)
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Journal Article
Individual differences in in vitro and in vivo metabolic clearances of the antipsychotic drug olanzapine from non-smoking and smoking Japanese subjects genotyped for cytochrome P4502D6 and flavincontaining monooxygenase 3
Okubo, Maho, Narita, Momoko, Murayama, Norie, Akimoto, Youichi, Goto, Akiko, Yamazaki, Hiroshi
Published in Human psychopharmacology (01.03.2016)
Published in Human psychopharmacology (01.03.2016)
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Journal Article
Effects of Vitamin D Receptor, Cytochrome P450 3A, and Cytochrome P450 Oxidoreductase Genetic Polymorphisms on the Pharmacokinetics of Remimazolam in Healthy Chinese Volunteers
Hu, Kun, Xiang, Qian, Wang, Zhe, Sheng, Xiaoyan, Li, Li'e, Liang, Yan, Zhao, Xia, Ye, Xia, Cui, Yimin
Published in Clinical pharmacology in drug development (01.01.2021)
Published in Clinical pharmacology in drug development (01.01.2021)
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Journal Article
Dose Adjustment in Patients with Liver Disease
Delc??, Fabiola, Tchambaz, Lydia, Schlienger, Raymond, Drewe, J??rgen, Kr??henb??hl, Stephan
Published in Drug safety (01.01.2005)
Published in Drug safety (01.01.2005)
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Journal Article
Effect of fosamprenavir/ritonavir on the pharmacokinetics of single-dose olanzapine in healthy volunteers
Jacobs, Birgit S., Colbers, Angela P.H., Velthoven-Graafland, Kirsten, Schouwenberg, Bas J.J.W., Burger, David M.
Published in International journal of antimicrobial agents (01.08.2014)
Published in International journal of antimicrobial agents (01.08.2014)
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Journal Article
A randomized, double-blind comparison of olanzapine/fluoxetine combination, olanzapine, fluoxetine, and venlafaxine in treatment-resistant depression
Corya, Sara A., Williamson, Doug, Sanger, Todd M., Briggs, Susan D., Case, Michael, Tollefson, Gary
Published in Depression and anxiety (2006)
Published in Depression and anxiety (2006)
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Journal Article