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Phase 2, Dose-Ranging Study of Relebactam with Imipenem-Cilastatin in Subjects with Complicated Intra-abdominal Infection
Lucasti, Christopher, Vasile, Liviu, Sandesc, Dorel, Venskutonis, Donatas, McLeroth, Patrick, Lala, Mallika, Rizk, Matthew L., Brown, Michelle L., Losada, Maria C., Pedley, Alison, Kartsonis, Nicholas A., Paschke, Amanda
Published in Antimicrobial agents and chemotherapy (01.10.2016)
Published in Antimicrobial agents and chemotherapy (01.10.2016)
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Journal Article
Safety of Ceftazidime-Avibactam in Combination with Aztreonam (COMBINE) in a Phase I, Open-Label Study in Healthy Adult Volunteers
Lodise, Thomas P., O’Donnell, J. Nicholas, Raja, Shruti, Guptill, Jeffrey T., Zaharoff, Smitha, Schwager, Nyssa, Fowler, Vance G., Beresnev, Tatiana, Wall, Alison, Wiegand, Katherine, Serti Chrisos, Elisavet, Balevic, Stephen, Chambers, Henry F.
Published in Antimicrobial agents and chemotherapy (20.12.2022)
Published in Antimicrobial agents and chemotherapy (20.12.2022)
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Journal Article
Phase 1 study assessing the steady-state concentration of ceftazidime and avibactam in plasma and epithelial lining fluid following two dosing regimens
Nicolau, David P., Siew, Leonard, Armstrong, Jon, Li, James, Edeki, Timi, Learoyd, Maria, Das, Shampa
Published in Journal of antimicrobial chemotherapy (01.10.2015)
Published in Journal of antimicrobial chemotherapy (01.10.2015)
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Journal Article
A randomised, double-blind, phase 3 study comparing the efficacy and safety of ceftazidime/avibactam plus metronidazole versus meropenem for complicated intra-abdominal infections in hospitalised adults in Asia
Qin, Xinyu, Tran, Binh Giang, Kim, Min Ja, Wang, Lie, Nguyen, Dung Anh, Chen, Qian, Song, Jie, Laud, Peter J., Stone, Gregory G., Chow, Joseph W.
Published in International journal of antimicrobial agents (01.05.2017)
Published in International journal of antimicrobial agents (01.05.2017)
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Journal Article
Pharmacokinetics, Safety, and Tolerability of Intravenous Durlobactam and Sulbactam in Subjects with Renal Impairment and Healthy Matched Control Subjects
O’Donnell, John, Preston, Richard A., Mamikonyan, Grigor, Stone, Emily, Isaacs, Robin
Published in Antimicrobial agents and chemotherapy (01.09.2019)
Published in Antimicrobial agents and chemotherapy (01.09.2019)
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Journal Article
Corticotropin-Releasing Factor Receptor 1 Antagonism Is Ineffective for Women With Posttraumatic Stress Disorder
Dunlop, Boadie W., Binder, Elisabeth B., Iosifescu, Dan, Mathew, Sanjay J., Neylan, Thomas C., Pape, Julius C., Carrillo-Roa, Tania, Green, Charles, Kinkead, Becky, Grigoriadis, Dimitri, Rothbaum, Barbara O., Nemeroff, Charles B., Mayberg, Helen S.
Published in Biological psychiatry (1969) (15.12.2017)
Published in Biological psychiatry (1969) (15.12.2017)
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Journal Article
A Mechanistic study assessing difficulty discontinuing chronic hypnotic use
Roehrs, Timothy, Koshorek, Gail, Sibai, Mohammad, Tabor, Aisha, Bazan, Luisa, Roth, Thomas
Published in Psychopharmacology (01.10.2025)
Published in Psychopharmacology (01.10.2025)
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Journal Article
Single-Center Evaluation of the Pharmacokinetics of WCK 5222 (Cefepime-Zidebactam Combination) in Subjects with Renal Impairment
Preston, Richard A., Mamikonyan, Grigor, DeGraff, Stephane, Chiou, James, Kemper, Christopher J., Xu, Allan, Mastim, Mushtaque, Yeole, Ravindra, Chavan, Rajesh, Patel, Anasuya, Friedland, H. David, Bhatia, Ashima
Published in Antimicrobial agents and chemotherapy (01.01.2019)
Published in Antimicrobial agents and chemotherapy (01.01.2019)
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Journal Article
Single-Dose Study of a Corticotropin-Releasing Factor Receptor-1 Antagonist in Women With 21-Hydroxylase Deficiency
Turcu, Adina F., Spencer-Segal, Joanna L., Farber, Robert H., Luo, Rosa, Grigoriadis, Dimitri E., Ramm, Carole A., Madrigal, David, Muth, Tim, O'Brien, Christopher F., Auchus, Richard J.
Published in The journal of clinical endocrinology and metabolism (01.03.2016)
Published in The journal of clinical endocrinology and metabolism (01.03.2016)
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Journal Article
Safety and Pharmacokinetics of Single and Multiple Ascending Doses of Avibactam Alone and in Combination with Ceftazidime in Healthy Male Volunteers: Results of Two Randomized, Placebo-Controlled Studies
Merdjan, Henri, Rangaraju, Manickam, Tarral, Antoine
Published in Clinical drug investigation (01.05.2015)
Published in Clinical drug investigation (01.05.2015)
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Journal Article
A randomized, double‐blind, placebo‐ and positive‐controlled crossover study of the effects of durlobactam on cardiac repolarization in healthy subjects
O’Donnell, John, Maloney, Kathleen, Steidler, Melissa, Morrison, Royce, Isaacs, Robin
Published in Clinical and translational science (01.07.2021)
Published in Clinical and translational science (01.07.2021)
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Journal Article
AQW051, a novel, potent and selective α7 nicotinic ACh receptor partial agonist: pharmacological characterization and phase I evaluation
Feuerbach, Dominik, Pezous, Nicole, Weiss, Markus, Shakeri‐Nejad, Kasra, Lingenhoehl, Kurt, Hoyer, Daniel, Hurth, Konstanze, Bilbe, Graeme, Pryce, Christopher R, McAllister, Kevin, Chaperon, Frederique, Kucher, Klaus, Johns, Donald, Blaettler, Thomas, Lopez Lopez, Cristina
Published in British journal of pharmacology (01.03.2015)
Published in British journal of pharmacology (01.03.2015)
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Journal Article
Withdrawal from long‐term use of zopiclone, zolpidem and temazepam may improve perceived sleep and quality of life in older adults with primary insomnia
Lähteenmäki, Ritva, Neuvonen, Pertti J., Puustinen, Juha, Vahlberg, Tero, Partinen, Markku, Räihä, Ismo, Kivelä, Sirkka‐Liisa
Published in Basic & clinical pharmacology & toxicology (01.03.2019)
Published in Basic & clinical pharmacology & toxicology (01.03.2019)
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Journal Article
Next‐day residual effects of flibanserin on simulated driving performance in premenopausal women
Kay, Gary G., Hochadel, Thomas, Sicard, Eric, Natarajan, Karthi K., Kim, Noel N.
Published in Human psychopharmacology (01.07.2017)
Published in Human psychopharmacology (01.07.2017)
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Journal Article
XL647—A Multitargeted Tyrosine Kinase Inhibitor: Results of a Phase II Study in Subjects with Non-small Cell Lung Cancer Who Have Progressed after Responding to Treatment with Either Gefitinib or Erlotinib
Pietanza, M. Catherine, Lynch, Thomas James, Lara, Primo N., Cho, John, Yanagihara, Ronald H., Vrindavanam, Nandagopal, Chowhan, Naveed Mahfooz, Gadgeel, Shirish M., Pennell, Nathan A., Funke, Roel, Mitchell, Ben, Wakelee, Heather A., Miller, Vincent A.
Published in Journal of thoracic oncology (01.01.2012)
Published in Journal of thoracic oncology (01.01.2012)
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Journal Article
A 12-Week, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Effect of Eszopiclone 2 mg on Sleep/Wake Function in Older Adults with Primary and Comorbid Insomnia
Ancoli-lsrael, Sonia, Krystal, Andrew D., McCall, W. Vaughn, Schaefer, Kendyl, Wilson, Amy, Claus, Raymond, Rubens, Robert, Roth, Thomas
Published in Sleep (New York, N.Y.) (01.02.2010)
Published in Sleep (New York, N.Y.) (01.02.2010)
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Journal Article
Phase I study assessing the safety, tolerability, and pharmacokinetics of avibactam and ceftazidime–avibactam in healthy Japanese volunteers
Tominaga, Nobumitsu, Edeki, Timi, Li, James, Learoyd, Maria, Bouw, M. René, Das, Shampa
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01.08.2015)
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01.08.2015)
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Journal Article