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Phase I Assessment of Safety and Therapeutic Activity of BAY1436032 in Patients with IDH1-Mutant Solid Tumors
Wick, Antje, Bähr, Oliver, Schuler, Martin, Rohrberg, Kristoffer, Chawla, Sant P., Janku, Filip, Schiff, David, Heinemann, Volker, Narita, Yoshitaka, Lenz, Heinz-Josef, Ikeda, Masafumi, Ando, Yuichi, Wick, Wolfgang, Steinbach, Joachim P., Burger, Michael C., Wenger, Katharina, Lassen, Ulrik, Sankhala, Kamalesh K., Roggia, Cristiana, Genvresse, Isabelle, Munhoz, Catya, Rentzsch, Christine, Reschke, Susanne, Langer, Simon, Wagner, Markus, Kaulfuss, Stefan, Cai, Charles, Lagkadinou, Eleni, Jeffers, Michael, Peña, Carol, Tabatabai, Ghazaleh
Published in Clinical cancer research (15.05.2021)
Published in Clinical cancer research (15.05.2021)
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Journal Article
Enhanced Benefit in Diabetic Macular Edema from AKB-9778 Tie2 Activation Combined with Vascular Endothelial Growth Factor Suppression
Campochiaro, Peter A., Khanani, Arshad, Singer, Michael, Patel, Sunil, Boyer, David, Dugel, Pravin, Kherani, Saleema, Withers, Barbara, Gambino, Laura, Peters, Kevin, Brigell, Mitchell
Published in Ophthalmology (Rochester, Minn.) (01.08.2016)
Published in Ophthalmology (Rochester, Minn.) (01.08.2016)
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Journal Article
Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations
Ikemura, Shinnosuke, Yasuda, Hiroyuki, Matsumoto, Shingo, Kamada, Mayumi, Hamamoto, Junko, Masuzawa, Keita, Kobayashi, Keigo, Manabe, Tadashi, Arai, Daisuke, Nakachi, Ichiro, Kawada, Ichiro, Ishioka, Kota, Nakamura, Morio, Namkoong, Ho, Naoki, Katsuhiko, Ono, Fumie, Araki, Mitsugu, Kanada, Ryo, Ma, Biao, Hayashi, Yuichiro, Mimaki, Sachiyo, Yoh, Kiyotaka, Kobayashi, Susumu S., Kohno, Takashi, Okuno, Yasushi, Goto, Koichi, Tsuchihara, Katsuya, Soejima, Kenzo
Published in Proceedings of the National Academy of Sciences - PNAS (14.05.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (14.05.2019)
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Journal Article
Safety and efficacy of BAY1436032 in IDH1-mutant AML: phase I study results
Heuser, Michael, Palmisiano, Neil, Mantzaris, Ioannis, Mims, Alice, DiNardo, Courtney, Silverman, Lewis R., Wang, Eunice S., Fiedler, Walter, Baldus, Claudia, Schwind, Sebastian, Pardee, Timothy, Perl, Alexander E., Cai, Charles, Kaulfuss, Stefan, Lagkadinou, Eleni, Rentzsch, Christine, Wagner, Markus, Wilkinson, Gary, Wu, Bingyan, Jeffers, Michael, Genvresse, Isabelle, Krämer, Alwin
Published in Leukemia (01.11.2020)
Published in Leukemia (01.11.2020)
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Journal Article
From the beginning to resistance: Study of plasma monitoring and resistance mechanisms in a cohort of patients treated with osimertinib for advanced T790M-positive NSCLC
Bordi, Paola, Del Re, Marzia, Minari, Roberta, Rofi, Eleonora, Buti, Sebastiano, Restante, Giuliana, Squadrilli, Anna, Crucitta, Stefania, Casartelli, Chiara, Gnetti, Letizia, Azzoni, Cinzia, Bottarelli, Lorena, Petrini, Iacopo, Cosenza, Agnese, Ferri, Leonarda, Rapacchi, Elena, Danesi, Romano, Tiseo, Marcello
Published in Lung cancer (Amsterdam, Netherlands) (01.05.2019)
Published in Lung cancer (Amsterdam, Netherlands) (01.05.2019)
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Journal Article
Osimertinib in Elderly Patients with Epidermal Growth Factor Receptor T790M‐Positive Non‐Small‐Cell Lung Cancer Who Progressed During Prior Treatment: A Phase II Trial
Nakao, Akira, Hiranuma, Osamu, Uchino, Junji, Sakaguchi, Chikara, Kita, Toshiyuki, Hiraoka, Noriya, Ishizuka, Tamotsu, Kubota, Yutaka, Kawasaki, Masayuki, Goto, Yasuhiro, Imai, Hisao, Hattori, Noboru, Nakatomi, Keita, Uramoto, Hidetaka, Uryu, Kiyoaki, Fukuda, Minoru, Uchida, Yasuki, Yokoyama, Toshihide, Akai, Masaya, Mio, Tadashi, Nagashima, Seiji, Chihara, Yusuke, Tamiya, Nobuyo, Kaneko, Yoshiko, Mouri, Takako, Yamada, Tadaaki, Yoshimura, Kenichi, Fujita, Masaki, Takayama, Koichi
Published in The oncologist (Dayton, Ohio) (01.05.2019)
Published in The oncologist (Dayton, Ohio) (01.05.2019)
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Journal Article
Therapeutic drug monitoring of osimertinib in EGFR mutant non‐small cell lung cancer by dried blood spot and plasma collection: A pilot study
Narayanan, Sathya, Yuile, Alexander, Venkatesh, Bharat, McKay, Matthew, Itchins, Malinda, Pavlakis, Nick, Wheeler, Helen, Gray, Lauren, Wei, Joe, Miller, Samuel, Kirwin, Brendan, Molloy, Mark P., Clarke, Stephen
Published in British journal of clinical pharmacology (01.08.2024)
Published in British journal of clinical pharmacology (01.08.2024)
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Journal Article
Orthotopic model of lung cancer: isolation of bone micro-metastases after tumor escape from Osimertinib treatment
Jarry, Ulrich, Bostoën, Mégane, Pineau, Raphaël, Chaillot, Laura, Mennessier, Valentine, Montagne, Pierre, Motte, Emilie, Gournay, Marjorie, Le Goff, Arnaud, Guillaudeux, Thierry, Pedeux, Rémy
Published in BMC cancer (10.05.2021)
Published in BMC cancer (10.05.2021)
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Journal Article
A Case Report of Successful Treatment With Crizotinib to Overcome Resistance to Osimertinib in an EGFR Mutated Non–Small-Cell Lung Cancer Patient Harboring an Acquired MET Exon 14 Mutation
Pinquie, François, Cortot, Alexis B., Chevalier, Louise-Marie, Morel, Alain, Sandrini, Jérémy, Guguen, Camille, Morvan, Benjamin, Molinier, Olivier
Published in Clinical lung cancer (01.03.2022)
Published in Clinical lung cancer (01.03.2022)
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Journal Article
A Phase II Trial of Osimertinib as the First-Line Treatment of Non–Small Cell Lung Cancer Harboring Activating EGFR Mutations in Circulating Tumor DNA: LiquidLung-O-Cohort 1
Park, Cheol-Kyu, Cho, Hyun-Ju, Choi, Yoo-Duk, Oh, In-Jae, Kim, Young-Chul
Published in Cancer research and treatment (01.01.2021)
Published in Cancer research and treatment (01.01.2021)
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Journal Article
Bosutinib in Combination With the Aromatase Inhibitor Letrozole: A Phase II Trial in Postmenopausal Women Evaluating First‐Line Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor‐Positive/HER2‐Negative Breast Cancer
Moy, Beverly, Neven, Patrick, Lebrun, Fabienne, Bellet, Meritxell, Xu, Binghe, Sarosiek, Tomasz, Chow, Louis, Goss, Paul, Zacharchuk, Charles, Leip, Eric, Turnbull, Kathleen, Bardy‐Bouxin, Nathalie, Duvillié, Ladan, Láng, István
Published in The oncologist (Dayton, Ohio) (01.04.2014)
Published in The oncologist (Dayton, Ohio) (01.04.2014)
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Journal Article
A phase I study of two dosing schedules of oral BI 847325 in patients with advanced solid tumors
Schöffski, Patrick, Aftimos, Philippe, Dumez, Herlinde, Deleporte, Amélie, De Block, Katrien, Costermans, Jo, Billiet, Maureen, Meeus, Marie-Anne, Lee, Chooi, Schnell, David, Goeldner, Rainer-Georg, Awada, Ahmad
Published in Cancer chemotherapy and pharmacology (01.01.2016)
Published in Cancer chemotherapy and pharmacology (01.01.2016)
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Journal Article
Effect of rifampin on the pharmacokinetics, safety and tolerability of navitoclax (ABT-263), a dual inhibitor of Bcl-2 and Bcl-XL, in patients with cancer
Yang, J., Pradhan, R. S., Rosen, L. S., Graham, A. M., Holen, K. D., Xiong, H.
Published in Journal of clinical pharmacy and therapeutics (01.12.2014)
Published in Journal of clinical pharmacy and therapeutics (01.12.2014)
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Journal Article
Effectiveness of Osimertinib in Patients with Lung Adenocarcinoma in Clinical Practice—The Expanded Drug Access Program in Poland
Knetki-Wróblewska, Magdalena, Kowalski, Dariusz, Czyżewicz, Grzegorz, Bryl, Maciej, Wrona, Anna, Dziadziuszko, Rafał, Kieszko, Robert, Milanowski, Janusz, Świniuch, Daria, Ramlau, Rodryg, Chmielowska, Ewa, Krzakowski, Maciej
Published in Advances in respiratory medicine (01.01.2020)
Published in Advances in respiratory medicine (01.01.2020)
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Journal Article
Effects of a putative antidepressant with a rapid onset of action in defeated mice with different coping strategies
Gómez-Lázaro, Eneritz, Garmendia, Larraitz, Beitia, Garikoitz, Perez-Tejada, Joana, Azpiroz, Arantza, Arregi, Amaia
Published in Progress in neuro-psychopharmacology & biological psychiatry (07.08.2012)
Published in Progress in neuro-psychopharmacology & biological psychiatry (07.08.2012)
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Journal Article
Population pharmacokinetics and association between A77 1726 plasma concentrations and disease activity measures following administration of leflunomide to people with rheumatoid arthritis
Chan, Vivien, Charles, Bruce G., Tett, Susan E.
Published in British journal of clinical pharmacology (01.09.2005)
Published in British journal of clinical pharmacology (01.09.2005)
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Journal Article
Effects of a Pharmacologically-Induced Shift of Hemoglobin-Oxygen Dissociation on Myocardial Energetics During Ischemia in Patients with Coronary Artery Disease
Najjar, Samer, Bottomley, Paul, Schulman, Steven, Waldron, Michele, Steffen, Robert, Gerstenblith, Gary, Weiss, Robert
Published in Journal of cardiovascular magnetic resonance (01.01.2005)
Published in Journal of cardiovascular magnetic resonance (01.01.2005)
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Journal Article