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An epigenetic blockade of cognitive functions in the neurodegenerating brain
Gräff, Johannes, Rei, Damien, Guan, Ji-Song, Wang, Wen-Yuan, Seo, Jinsoo, Hennig, Krista M., Nieland, Thomas J. F., Fass, Daniel M., Kao, Patricia F., Kahn, Martin, Su, Susan C., Samiei, Alireza, Joseph, Nadine, Haggarty, Stephen J., Delalle, Ivana, Tsai, Li-Huei
Published in Nature (London) (08.03.2012)
Published in Nature (London) (08.03.2012)
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Journal Article
Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles
Joshi, P, Turola, E, Ruiz, A, Bergami, A, Libera, D D, Benussi, L, Giussani, P, Magnani, G, Comi, G, Legname, G, Ghidoni, R, Furlan, R, Matteoli, M, Verderio, C
Published in Cell death and differentiation (01.04.2014)
Published in Cell death and differentiation (01.04.2014)
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Journal Article
d-serine levels in Alzheimer’s disease: implications for novel biomarker development
Madeira, C, Lourenco, M V, Vargas-Lopes, C, Suemoto, C K, Brandão, C O, Reis, T, Leite, R E P, Laks, J, Jacob-Filho, W, Pasqualucci, C A, Grinberg, L T, Ferreira, S T, Panizzutti, R
Published in Translational psychiatry (05.05.2015)
Published in Translational psychiatry (05.05.2015)
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Journal Article
Biochemical stages of amyloid-β peptide aggregation and accumulation in the human brain and their association with symptomatic and pathologically preclinical Alzheimer’s disease
Rijal Upadhaya, Ajeet, Kosterin, Irina, Kumar, Sathish, von Arnim, Christine A. F., Yamaguchi, Haruyasu, Fändrich, Marcus, Walter, Jochen, Thal, Dietmar Rudolf
Published in Brain (London, England : 1878) (01.03.2014)
Published in Brain (London, England : 1878) (01.03.2014)
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Journal Article
Protection from Amyloid β Peptide–Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor
Cui, Su-Ying, Yang, Ming-Xin, Zhang, Yong-He, Zheng, Victor, Zhang, Han-Ting, Gurney, Mark E., Xu, Ying, O’Donnell, James M.
Published in The Journal of pharmacology and experimental therapeutics (01.11.2019)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2019)
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Journal Article
Evidence of fibril-like β-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid
Chimon, Sandra, Shaibat, Medhat A, Jones, Christopher R, Calero, Diana C, Aizezi, Buzulagu, Ishii, Yoshitaka
Published in Nature structural & molecular biology (01.12.2007)
Published in Nature structural & molecular biology (01.12.2007)
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Journal Article
Protein N-homocysteinylation: From cellular toxicity to neurodegeneration
Sharma, Gurumayum Suraj, Kumar, Tarun, Dar, Tanveer Ali, Singh, Laishram Rajendrakumar
Published in Biochimica et biophysica acta (01.11.2015)
Published in Biochimica et biophysica acta (01.11.2015)
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Journal Article
Amyloid-β Increases Tau by Mediating Sirtuin 3 in Alzheimer’s Disease
Yin, Junxiang, Han, Pengcheng, Song, Melissa, Nielsen, Megan, Beach, Thomas G., Serrano, Geidy E., Liang, Winnie S., Caselli, Richard J., Shi, Jiong
Published in Molecular neurobiology (01.11.2018)
Published in Molecular neurobiology (01.11.2018)
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Journal Article
Monoclonal antibody with conformational specificity for a toxic conformer of amyloid β42 and its application toward the Alzheimer’s disease diagnosis
Murakami, Kazuma, Tokuda, Maki, Suzuki, Takashi, Irie, Yumi, Hanaki, Mizuho, Izuo, Naotaka, Monobe, Yoko, Akagi, Ken-ichi, Ishii, Ryotaro, Tatebe, Harutsugu, Tokuda, Takahiko, Maeda, Masahiro, Kume, Toshiaki, Shimizu, Takahiko, Irie, Kazuhiro
Published in Scientific reports (04.07.2016)
Published in Scientific reports (04.07.2016)
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Journal Article
Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal
Tang, Sung-Chun, Lathia, Justin D., Selvaraj, Pradeep K., Jo, Dong-Gyu, Mughal, Mohamed R., Cheng, Aiwu, Siler, Dominic A., Markesbery, William R., Arumugam, Thiruma V., Mattson, Mark P.
Published in Experimental neurology (01.09.2008)
Published in Experimental neurology (01.09.2008)
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Journal Article
A single-domain antibody detects and neutralises toxic Aβ 42 oligomers in the Alzheimer's disease CSF
Bigi, Alessandra, Napolitano, Liliana, Vadukul, Devkee M, Chiti, Fabrizio, Cecchi, Cristina, Aprile, Francesco A, Cascella, Roberta
Published in Alzheimer's research & therapy (18.01.2024)
Published in Alzheimer's research & therapy (18.01.2024)
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Journal Article
Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-β oligomers
Gandy, Sam, Simon, Adam J., Steele, John W., Lublin, Alex L., Lah, James J., Walker, Lary C., Levey, Allan I., Krafft, Grant A., Levy, Efrat, Checler, Frédéric, Glabe, Charles, Bilker, Warren B., Abel, Ted, Schmeidler, James, Ehrlich, Michelle E.
Published in Annals of neurology (01.08.2010)
Published in Annals of neurology (01.08.2010)
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Journal Article
Amyloid β toxic conformer has dynamic localization in the human inferior parietal cortex in absence of amyloid plaques
Kageyama, Yusuke, Saito, Atsushi, Pletnikova, Olga, Rudow, Gay L., Irie, Yumi, An, Yang, Murakami, Kazuma, Irie, Kazuhiro, Resnick, Susan M., Fowler, David R., Martin, Lee J., Troncoso, Juan C.
Published in Scientific reports (15.11.2018)
Published in Scientific reports (15.11.2018)
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Journal Article
Toxic Role of K + Channel Oxidation in Mammalian Brain
Cotella, Diego, Hernandez-Enriquez, Berenice, Wu, Xilong, Li, Ruiqiong, Pan, Zui, Leveille, Joseph, Link, Christopher D., Oddo, Salvatore, Sesti, Federico
Published in The Journal of neuroscience (21.03.2012)
Published in The Journal of neuroscience (21.03.2012)
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Journal Article
The cell-permeable Aβ1-6A2VTAT(D) peptide reverts synaptopathy induced by Aβ1-42wt
Cimini, Sara, Sclip, Alessandra, Mancini, Simona, Colombo, Laura, Messa, Massimo, Cagnotto, Alfredo, Di Fede, Giuseppe, Tagliavini, Fabrizio, Salmona, Mario, Borsello, Tiziana
Published in Neurobiology of disease (01.05.2016)
Published in Neurobiology of disease (01.05.2016)
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Journal Article
Mechanism of neuroprotection of melatonin against beta-amyloid neurotoxicity
Ionov, M., Burchell, V., Klajnert, B., Bryszewska, M., Abramov, A.Y.
Published in Neuroscience (28.04.2011)
Published in Neuroscience (28.04.2011)
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Journal Article