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Blood‐based quantification of Aβ oligomers indicates impaired clearance from brain in ApoE ε4 positive subjects
Willbold, Dieter, Blömeke, Lara, Rehn, Fabian, Pils, Marlene, Kraemer‐Schulien, Victoria, Kutzsche, Janine, Bujnicki, Tuyen, Priller, Josef, Schneider, Anja, Wiltfang, Jens, Jessen, Frank, Düzel, Emrah, Bürger, Katharina, Perneczky, Robert, Teipel, Stefan, Laske, Christoph, Spottke, Annika, Wagner, Michael, Peters, Oliver, Bannach, Oliver
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
Blood-based quantification of Aβ oligomers indicates impaired clearance from brain in ApoE ε4 positive subjects
Blömeke, Lara, Rehn, Fabian, Pils, Marlene, Kraemer-Schulien, Victoria, Cousin, Anneliese, Kutzsche, Janine, Bujnicki, Tuyen, Freiesleben, Silka D., Schneider, Luisa-Sophie, Preis, Lukas, Priller, Josef, Spruth, Eike J., Altenstein, Slawek, Schneider, Anja, Fliessbach, Klaus, Wiltfang, Jens, Hansen, Niels, Rostamzadeh, Ayda, Düzel, Emrah, Glanz, Wenzel, Incesoy, Enise I., Buerger, Katharina, Janowitz, Daniel, Ewers, Michael, Perneczky, Robert, Rauchmann, Boris-Stephan, Teipel, Stefan, Kilimann, Ingo, Laske, Christoph, Munk, Matthias H., Spottke, Annika, Roy, Nina, Heneka, Michael T., Brosseron, Frederic, Wagner, Michael, Roeske, Sandra, Ramirez, Alfredo, Schmid, Matthias, Jessen, Frank, Bannach, Oliver, Peters, Oliver, Willbold, Dieter
Published in Communications medicine (10.12.2024)
Published in Communications medicine (10.12.2024)
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Journal Article
Removal of Aβ Oligomers from the Blood: A Potential Therapeutic System for Alzheimer’s Disease
Saito, Yuta, Sakata, Miwa, Kobayakawa, Moe, Kawachi, Hiroshi, Kawaguchi, Kazunori, Hiki, Yoshiyuki, Kato, Masao, Mori, Mayuko, Hasegawa, Midori, Ohashi, Norimi, Yuzawa, Yukio, Kitaguchi, Nobuya
Published in Neuropsychiatric disease and treatment (01.01.2020)
Published in Neuropsychiatric disease and treatment (01.01.2020)
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Journal Article
Astrocyte Transforming Growth Factor Beta 1 Protects Synapses against Aβ Oligomers in Alzheimer's Disease Model
Pereira Diniz, Luan, Tortelli, Vanessa, Matias, Isadora, Morgado, Juliana, Bérgamo Araujo, Ana Paula, Melo, Helen M., Seixas da Silva, Gisele S., Alves-Leon, Soniza V., de Souza, Jorge M., Ferreira, Sergio T., De Felice, Fernanda G., Gomes, Flávia Carvalho Alcantara
Published in The Journal of neuroscience (12.07.2017)
Published in The Journal of neuroscience (12.07.2017)
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Journal Article
An ultra‐sensitive immunoassay detects and quantifies soluble Aβ oligomers in human plasma
Liu, Lei, Kwak, Hyunchang, Lawton, Trebor L., Jin, Shan‐Xue, Meunier, Angela L., Dang, Yifan, Ostaszewski, Beth, Pietras, Alison C., Stern, Andrew M., Selkoe, Dennis J.
Published in Alzheimer's & dementia (01.06.2022)
Published in Alzheimer's & dementia (01.06.2022)
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Journal Article
Aβ oligomers peak in early stages of Alzheimer's disease preceding tau pathology
Blömeke, Lara, Rehn, Fabian, Kraemer‐Schulien, Victoria, Kutzsche, Janine, Pils, Marlene, Bujnicki, Tuyen, Lewczuk, Piotr, Kornhuber, Johannes, Freiesleben, Silka D., Schneider, Luisa‐Sophie, Preis, Lukas, Priller, Josef, Spruth, Eike J., Altenstein, Slawek, Lohse, Andrea, Schneider, Anja, Fliessbach, Klaus, Wiltfang, Jens, Hansen, Niels, Rostamzadeh, Ayda, Düzel, Emrah, Glanz, Wenzel, Incesoy, Enise I., Butryn, Michaela, Buerger, Katharina, Janowitz, Daniel, Ewers, Michael, Perneczky, Robert, Rauchmann, Boris‐Stephan, Teipel, Stefan, Kilimann, Ingo, Goerss, Doreen, Laske, Christoph, Munk, Matthias H., Sanzenbacher, Carolin, Spottke, Annika, Roy‐Kluth, Nina, Heneka, Michael T., Brosseron, Frederic, Wagner, Michael, Wolfsgruber, Steffen, Kleineidam, Luca, Stark, Melina, Schmid, Matthias, Jessen, Frank, Bannach, Oliver, Willbold, Dieter, Peters, Oliver
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (01.04.2024)
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (01.04.2024)
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Journal Article
Aβ Oligomers Induce Neuronal Cell Cycle Events in Alzheimer's Disease
Varvel, Nicholas H., Bhaskar, Kiran, Patil, Anita R., Pimplikar, Sanjay W., Herrup, Karl, Lamb, Bruce T.
Published in The Journal of neuroscience (22.10.2008)
Published in The Journal of neuroscience (22.10.2008)
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Journal Article
Novel APP/Aβ mutation K16N produces highly toxic heteromeric Aβ oligomers
Kaden, Daniela, Harmeier, Anja, Weise, Christoph, Munter, Lisa M., Althoff, Veit, Rost, Benjamin R., Hildebrand, Peter W., Schmitz, Dietmar, Schaefer, Michael, Lurz, Rudi, Skodda, Sabine, Yamamoto, Raina, Arlt, Sönke, Finckh, Ulrich, Multhaup, Gerd
Published in EMBO molecular medicine (01.07.2012)
Published in EMBO molecular medicine (01.07.2012)
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Journal Article
Are antibodies directed against amyloid-β (Aβ) oligomers the last call for the Aβ hypothesis of Alzheimer's disease?
Panza, Francesco, Lozupone, Madia, Dibello, Vittorio, Greco, Antonio, Daniele, Antonio, Seripa, Davide, Logroscino, Giancarlo, Imbimbo, Bruno P
Published in Immunotherapy (01.01.2019)
Published in Immunotherapy (01.01.2019)
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Journal Article
Dysregulated phosphorylation of Ca2+/calmodulin‐dependent protein kinase II‐α in the hippocampus of subjects with mild cognitive impairment and Alzheimer’s disease
Reese, Lindsay C., Laezza, Fernanda, Woltjer, Randall, Taglialatela, Giulio
Published in Journal of neurochemistry (01.11.2011)
Published in Journal of neurochemistry (01.11.2011)
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Journal Article
Dysregulated phosphorylation of Ca(2+) /calmodulin-dependent protein kinase II-α in the hippocampus of subjects with mild cognitive impairment and Alzheimer's disease
Reese, Lindsay C, Laezza, Fernanda, Woltjer, Randall, Taglialatela, Giulio
Published in Journal of neurochemistry (01.11.2011)
Published in Journal of neurochemistry (01.11.2011)
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Journal Article
Soluble Aβ Oligomers Impair Dipolar Heterodendritic Plasticity by Activation of mGluR in the Hippocampal CA1 Region
Zhao, Jianhua, Li, Anna, Rajsombath, Molly, Dang, Yifan, Selkoe, Dennis J., Li, Shaomin
Published in iScience (31.08.2018)
Published in iScience (31.08.2018)
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Journal Article
Results from COG0201: A Randomized, Double‐Blind, Placebo‐Controlled, Parallel‐ Group, Phase 2 Study to Evaluate the Safety and Efficacy of CT1812 in Subjects with Mild to Moderate Alzheimer’s Disease
Vijverberg, Everard G.B., Catalano, Susan, Hamby, Mary E., Grundman, Michael, Iaci, Jennifer, Devins, Theresa, Caggiano, Anthony O
Published in Alzheimer's & dementia (01.12.2024)
Published in Alzheimer's & dementia (01.12.2024)
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Journal Article
The cell-permeable Aβ1-6A2VTAT(D) peptide reverts synaptopathy induced by Aβ1-42wt
Cimini, Sara, Sclip, Alessandra, Mancini, Simona, Colombo, Laura, Messa, Massimo, Cagnotto, Alfredo, Di Fede, Giuseppe, Tagliavini, Fabrizio, Salmona, Mario, Borsello, Tiziana
Published in Neurobiology of disease (01.05.2016)
Published in Neurobiology of disease (01.05.2016)
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Journal Article
Removal of Aβ Oligomers from the Blood: A Potential Therapeutic System for Alzheimer’s Disease
Yuta Saito, Miwa Sakata, Moe Kobayakawa, Hiroshi Kawachi, Kazunori Kawaguchi, Yoshiyuki Hiki, Masao Kato, Mayuko Mori, Midori Hasegawa, Norimi Ohashi, Yukio Yuzawa, Nobuya Kitaguchi
Published in Neuropsychiatric Disease and Treatment (01.03.2020)
Published in Neuropsychiatric Disease and Treatment (01.03.2020)
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Journal Article
Absence of amyloid β oligomers at the postsynapse and regulated synaptic Zn2+ in cognitively intact aged individuals with Alzheimer’s disease neuropathology
Bjorklund, Nicole L, Reese, Lindsay C, Sadagoparamanujam, V-M, Ghirardi, Valeria, Woltjer, Randall L, Taglialatela, Giulio
Published in Molecular neurodegeneration (28.05.2012)
Published in Molecular neurodegeneration (28.05.2012)
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