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Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus
Hasni, Sarfaraz A., Gupta, Sarthak, Davis, Michael, Poncio, Elaine, Temesgen-Oyelakin, Yenealem, Carlucci, Philip M., Wang, Xinghao, Naqi, Mohammad, Playford, Martin P., Goel, Rishi R., Li, Xiaobai, Biehl, Ann J., Ochoa-Navas, Isabel, Manna, Zerai, Shi, Yinghui, Thomas, Donald, Chen, Jinguo, Biancotto, Angélique, Apps, Richard, Cheung, Foo, Kotliarov, Yuri, Babyak, Ashley L., Zhou, Huizhi, Shi, Rongye, Stagliano, Katie, Tsai, Wanxia Li, Vian, Laura, Gazaniga, Nathalia, Giudice, Valentina, Lu, Shajia, Brooks, Stephen R., MacKay, Meggan, Gregersen, Peter, Mehta, Nehal N., Remaley, Alan T., Diamond, Betty, O’Shea, John J., Gadina, Massimo, Kaplan, Mariana J.
Published in Nature communications (07.06.2021)
Published in Nature communications (07.06.2021)
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Journal Article
ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling
Gentili, Matteo, Liu, Bingxu, Papanastasiou, Malvina, Dele-Oni, Deborah, Schwartz, Marc A., Carlson, Rebecca J., Al’Khafaji, Aziz M., Krug, Karsten, Brown, Adam, Doench, John G., Carr, Steven A., Hacohen, Nir
Published in Nature communications (04.02.2023)
Published in Nature communications (04.02.2023)
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Journal Article
Biological fermentation pilot-scale systems and evaluation for commercial viability towards sustainable biohydrogen production
Zhang, Quanguo, Jiao, Youzhou, He, Chao, Ruan, Roger, Hu, Jianjun, Ren, Jingzheng, Toniolo, Sara, Jiang, Danping, Lu, Chaoyang, Li, Yameng, Man, Yi, Zhang, Huan, Zhang, Zhiping, Xia, Chenxi, Wang, Yi, Jing, Yanyan, Zhang, Xueting, Lin, Ruojue, Li, Gang, Yue, Jianzhi, Tahir, Nadeem
Published in Nature communications (28.05.2024)
Published in Nature communications (28.05.2024)
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Journal Article
Subtype-specific regulatory network rewiring in acute myeloid leukemia
Assi, Salam A., Imperato, Maria Rosaria, Coleman, Daniel J. L., Pickin, Anna, Potluri, Sandeep, Ptasinska, Anetta, Chin, Paulynn Suyin, Blair, Helen, Cauchy, Pierre, James, Sally R., Zacarias-Cabeza, Joaquin, Gilding, L. Niall, Beggs, Andrew, Clokie, Sam, Loke, Justin C., Jenkin, Phil, Uddin, Ash, Delwel, Ruud, Richards, Stephen J., Raghavan, Manoj, Griffiths, Michael J., Heidenreich, Olaf, Cockerill, Peter N., Bonifer, Constanze
Published in Nature genetics (01.01.2019)
Published in Nature genetics (01.01.2019)
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Journal Article
Potential depression and antidepressant-response biomarkers in human lymphoblast cell lines from treatment-responsive and treatment-resistant subjects: roles of SSRIs and omega-3 polyunsaturated fatty acids
Chukaew, Phatcharee, Leow, Alex, Saengsawang, Witchuda, Rasenick, Mark M.
Published in Molecular psychiatry (01.06.2021)
Published in Molecular psychiatry (01.06.2021)
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Journal Article
Circulating miR-155, miR-145 and let-7c as diagnostic biomarkers of the coronary artery disease
Faccini, Julien, Ruidavets, Jean-Bernard, Cordelier, Pierre, Martins, Frédéric, Maoret, Jean-José, Bongard, Vanina, Ferrières, Jean, Roncalli, Jérôme, Elbaz, Meyer, Vindis, Cécile
Published in Scientific reports (16.02.2017)
Published in Scientific reports (16.02.2017)
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Journal Article
Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood
Yuan, Xunmei, Tsujimoto, Kazutaka, Hashimoto, Koshi, Kawahori, Kenichi, Hanzawa, Nozomi, Hamaguchi, Miho, Seki, Takami, Nawa, Makiko, Ehara, Tatsuya, Kitamura, Yohei, Hatada, Izuho, Konishi, Morichika, Itoh, Nobuyuki, Nakagawa, Yoshimi, Shimano, Hitoshi, Takai-Igarashi, Takako, Kamei, Yasutomi, Ogawa, Yoshihiro
Published in Nature communications (12.02.2018)
Published in Nature communications (12.02.2018)
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Journal Article
Acute and long-term exercise adaptation of adipose tissue and skeletal muscle in humans: a matched transcriptomics approach after 8-week training-intervention
Dreher, Simon I., Irmler, Martin, Pivovarova-Ramich, Olga, Kessler, Katharina, Jürchott, Karsten, Sticht, Carsten, Fritsche, Louise, Schneeweiss, Patrick, Machann, Jürgen, Pfeiffer, Andreas F. H., Hrabě de Angelis, Martin, Beckers, Johannes, Birkenfeld, Andreas L., Peter, Andreas, Niess, Andreas M., Weigert, Cora, Moller, Anja
Published in International Journal of Obesity (01.04.2023)
Published in International Journal of Obesity (01.04.2023)
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Journal Article
The contribution of de novo coding mutations to meningomyelocele
Ha, Yoo-Jin Jiny, Nisal, Ashna, Tang, Isaac, Lee, Chanjae, Jhamb, Ishani, Wallace, Cassidy, Howarth, Robyn, Schroeder, Sarah, Vong, Keng Ioi, Meave, Naomi, Jiwani, Fiza, Barrows, Chelsea, Lee, Sangmoon, Jiang, Nan, Patel, Arzoo, Bagga, Krisha, Banka, Niyati, Friedman, Liana, Blanco, Francisco A., Yu, Seyoung, Rhee, Soeun, Jeong, Hui Su, Plutzer, Isaac, Major, Michael B., Benoit, Béatrice, Poüs, Christian, Heffner, Caleb, Kibar, Zoha, Bot, Gyang Markus, Northrup, Hope, Au, Kit Sing, Strain, Madison, Ashley-Koch, Allison E., Finnell, Richard H., Le, Joan T., Meltzer, Hal S., Araujo, Camila, Machado, Helio R., Stevenson, Roger E., Yurrita, Anna, Mumtaz, Sara, Ahmed, Awais, Khara, Mulazim Hussain, Mutchinick, Osvaldo M., Medina-Bereciartu, José Ramón, Hildebrandt, Friedhelm, Melikishvili, Gia, Marwan, Ahmed I., Capra, Valeria, Noureldeen, Mahmoud M., Salem, Aida M. S., Issa, Mahmoud Y., Zaki, Maha S., Xu, Libin, Lee, Ji Eun, Shin, Donghyuk, Alkelai, Anna, Shuldiner, Alan R., Kingsmore, Stephen F., Murray, Stephen A., Gee, Heon Yung, Miller, W. Todd, Tolias, Kimberley F., Wallingford, John B., Kim, Sangwoo, Gleeson, Joseph G.
Published in Nature (London) (08.05.2025)
Published in Nature (London) (08.05.2025)
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Journal Article
Identification of miRNAs and their targets in wild tomato at moderately and acutely elevated temperatures by high-throughput sequencing and degradome analysis
Zhou, Rong, Wang, Qian, Jiang, Fangling, Cao, Xue, Sun, Mintao, Liu, Min, Wu, Zhen
Published in Scientific reports (22.09.2016)
Published in Scientific reports (22.09.2016)
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Journal Article
Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target
Caldi Gomes, Lucas, Hänzelmann, Sonja, Hausmann, Fabian, Khatri, Robin, Oller, Sergio, Parvaz, Mojan, Tzeplaeff, Laura, Pasetto, Laura, Gebelin, Marie, Ebbing, Melanie, Holzapfel, Constantin, Columbro, Stefano Fabrizio, Scozzari, Serena, Knöferle, Johanna, Cordts, Isabell, Demleitner, Antonia F., Deschauer, Marcus, Dufke, Claudia, Sturm, Marc, Zhou, Qihui, Zelina, Pavol, Sudria-Lopez, Emma, Haack, Tobias B., Streb, Sebastian, Kuzma-Kozakiewicz, Magdalena, Edbauer, Dieter, Pasterkamp, R. Jeroen, Laczko, Endre, Rehrauer, Hubert, Schlapbach, Ralph, Carapito, Christine, Bonetto, Valentina, Bonn, Stefan, Lingor, Paul
Published in Nature communications (07.06.2024)
Published in Nature communications (07.06.2024)
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Journal Article
Identification of potential blood biomarkers associated with suicide in major depressive disorder
Mamdani, Firoza, Weber, Matthieu D., Bunney, Blynn, Burke, Kathleen, Cartagena, Preston, Walsh, David, Lee, Francis S., Barchas, Jack, Schatzberg, Alan F., Myers, Richard M., Watson, Stanley J., Akil, Huda, Vawter, Marquis P., Bunney, William E., Sequeira, Adolfo
Published in Translational psychiatry (14.04.2022)
Published in Translational psychiatry (14.04.2022)
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Journal Article
Allele-specific expression and high-throughput reporter assay reveal functional genetic variants associated with alcohol use disorders
Rao, Xi, Thapa, Kriti S., Chen, Andy B., Lin, Hai, Gao, Hongyu, Reiter, Jill L., Hargreaves, Katherine A., Ipe, Joseph, Lai, Dongbing, Xuei, Xiaoling, Wang, Yue, Gu, Hongmei, Kapoor, Manav, Farris, Sean P., Tischfield, Jay, Foroud, Tatiana, Goate, Alison M., Skaar, Todd C., Mayfield, R. Dayne, Edenberg, Howard J., Liu, Yunlong
Published in Molecular psychiatry (01.04.2021)
Published in Molecular psychiatry (01.04.2021)
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Journal Article
Commensal gut bacteria modulate phosphorylation-dependent PPARγ transcriptional activity in human intestinal epithelial cells
Nepelska, Malgorzata, de Wouters, Tomas, Jacouton, Elsa, Béguet-Crespel, Fabienne, Lapaque, Nicolas, Doré, Joël, Arulampalam, Velmurugesan, Blottière, Hervé M.
Published in Scientific reports (07.03.2017)
Published in Scientific reports (07.03.2017)
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Journal Article
Decoupling of degradation from deadenylation reshapes poly(A) tail length in yeast meiosis
Wiener, David, Antebi, Yaron, Schwartz, Schraga
Published in Nature structural & molecular biology (01.12.2021)
Published in Nature structural & molecular biology (01.12.2021)
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Journal Article
Childhood sleep duration modifies the polygenic risk for obesity in youth through leptin pathway: the Beijing Child and Adolescent Metabolic Syndrome cohort study
Fu, Junling, Wang, Yonghui, Li, Ge, Han, Lanwen, Li, Yu, Li, Lujiao, Feng, Dan, Wu, Yunpeng, Xiao, Xinhua, Li, Mingyao, Grant, Struan F. A., Li, Ming, Gao, Shan
Published in International Journal of Obesity (01.08.2019)
Published in International Journal of Obesity (01.08.2019)
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Journal Article
TLR9 activation in large wound induces tissue repair and hair follicle regeneration via γδT cells
Li, Xinhui, An, Tiantian, Yang, Yang, Xu, Zhaoyu, Chen, Shuaidong, Yi, Zumu, Deng, Chen, Zhou, Feng, Man, Yi, Hu, Chen
Published in Cell death & disease (17.08.2024)
Published in Cell death & disease (17.08.2024)
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Journal Article
Spectrum of cutaneous adverse reactions to aromatic antiepileptic drugs and human leukocyte antigen genotypes in Thai patients and meta-analysis
Sukasem, Chonlaphat, Sririttha, Suthida, Chaichan, Chonlawat, Nakkrut, Thapanat, Satapornpong, Patompong, Jaruthamsophon, Kanoot, Jantararoungtong, Thawinee, Koomdee, Napatrupron, Medhasi, Sadeep, Oo-Puthinan, Sarawut, Rerkpattanapipat, Ticha, Klaewsongkram, Jettanong, Rerknimitr, Pawinee, Tuchinda, Papapit, Chularojanamontri, Leena, Tovanabutra, Napatra, Suvannang, Naravut, Rungrotmongkol, Thanyada, Saokaew, Surasak, Aekplakorn, Wichai, Puangpetch, Apichaya
Published in The pharmacogenomics journal (01.12.2021)
Published in The pharmacogenomics journal (01.12.2021)
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Journal Article
Treatment of Necrotic Teeth by Apical Revascularization: Meta-analysis
He, Ling, Zhong, Juan, Gong, Qimei, Kim, Sahng G., Zeichner, Samuel J., Xiang, Lusai, Ye, Ling, Zhou, Xuedong, Zheng, Jinxuan, Liu, Yongxing, Guan, Chenyu, Cheng, Bin, Ling, Junqi, Mao, Jeremy J.
Published in Scientific reports (24.10.2017)
Published in Scientific reports (24.10.2017)
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Journal Article
Whole exome sequencing analysis identifies novel Stargardt disease-related gene mutations in Chinese Stargardt disease and retinitis pigmentosa patients
Ng, Tsz Kin, Cao, Yingjie, Yuan, Xiang-Ling, Chen, Shaowan, Xu, Yanxuan, Chen, Shao-Lang, Zheng, Yuqian, Chen, Haoyu
Published in Eye (London) (01.04.2022)
Published in Eye (London) (01.04.2022)
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Journal Article