rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Development of kinetic and anatomical models for brain dosimetry for internally deposited radionucldies
  name:
    name part: National Council on Radiation Protection and Measurements
    role:
      role term: editor.
  type of resource: text
  genre: bibliography
  genre: elektronické knihy
  genre: electronic books
  origin info:
    place:
      place term: mdu
    date issued: 2021
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource.
  abstract: "This Commentary examines current information on the accumulation, distribution, and retention of radionuclides in the brain and the extent to which that information can be used to improve estimates of dose to potentially radiosensitive regions of the brain from internal emitters, with emphasis on high linear-energy transfer (LET) alpha particle-emitting radionuclides. Dose estimates for the brain based on explicit brain models reflecting best available biokinetic data are compared with estimates based on the brain models typically used in radiation protection and dose reconstruction. The comparisons indicate that predictions of brain doses based on current models for radionuclides may substantially underestimate or overestimate brain dose projections based on an explicit brain model reflecting best available biokinetic data. Potential improvements in dose estimates for the brain based on more detailed dosimetric models of the brain are also examined. Improved estimates of radiation doses to brain based on more realistic biokinetic and dosimetric representations of the brain would be an important step forward in ongoing epidemiologic research aimed at evaluating dementia, Alzheimer's, Parkinson's, motor neuron diseases and cognitive impairment as possible adverse effects of radionuclide depositions in the brain"--
  table of contents: Structure and Functions of the Brain -- How Radionuclides Enter the Brain -- Illustrations of Available Biokinetic Data for Brain -- Case Studies of the Effect of Explicit Modeling of Brain Kinetics on Dose Estimates for Internal Emitters -- Potential Improvements in Dosimetric Models of the Brain for Internal Emitters.
  note: [edited by] National Council on Radiation Protection and Measurements.
  note: Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty
  note: Includes bibliographical references.
  subject:
    topic: Brain
    topic: radiation effects
  subject:
    topic: Radioisotopes
    topic: administration & dosage
  subject:
    topic: Radiation
    topic: Measurement
  related item:
    title info:
      title: Development of kinetic and anatomical models for brain dosimetry for internally deposited radionucldies
    origin info:
      publisher: Bethesda, Maryland : National Council on Radiation Protection and Measurements, February 20, 2021
    identifier: (DLC) 2021060523
  related item:
    title info:
      title: NCRP commentary ; no. 31
  identifier: 9781944888299
  identifier: 1944888292
  identifier: 9781944888282
  identifier: 1523145676
  identifier: 9781523145676
  identifier: https://proxy.k.utb.cz/login
  access condition: Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty
  record info:
    record content source: DLC
    record creation date: 220104
    record change date: 20240717213016.0
    record identifier: kn-on1291601759
    language of cataloging:
      language term: eng