Development of kinetic and anatomical models for brain dosimetry for internally deposited radionucldies

"This Commentary examines current information on the accumulation, distribution, and retention of radionuclides in the brain and the extent to which that information can be used to improve estimates of dose to potentially radiosensitive regions of the brain from internal emitters, with emphasis...

Full description

Saved in:
Bibliographic Details
Corporate Author: National Council on Radiation Protection and Measurements, (Editor)
Format: eBook
Language: English
Published: Bethesda, Maryland : National Council on Radiation Protection and Measurements, February 20, 2021
Series: NCRP commentary ; no. 31.
Subjects:
Brain > radiation effects.
Radioisotopes > administration & dosage.
Radiation > Measurement.
elektronické knihy
electronic books
ISBN: 9781944888299
1944888292
9781944888282
1523145676
9781523145676
Physical Description: 1 online resource.

Cover

Table of contents

LEADER 03773cam a22004458i 4500
001 kn-on1291601759
003 OCoLC
005 20240717213016.0
006 m o d
007 cr cn|||||||||
008 220104s2021 mdu ob 000 0 eng
040 |a DLC  |b eng  |e rda  |c DLC  |d OCLCO  |d SFB 
020 |a 9781944888299  |q (pdf) 
020 |a 1944888292 
020 |z 9781944888282  |q (paperback) 
020 |a 1523145676 
020 |a 9781523145676 
035 |a (OCoLC)1291601759  |z (OCoLC)1291608093  |z (OCoLC)1350305418 
042 |a pcc 
245 0 0 |a Development of kinetic and anatomical models for brain dosimetry for internally deposited radionucldies /  |c [edited by] National Council on Radiation Protection and Measurements. 
264 1 |a Bethesda, Maryland :  |b National Council on Radiation Protection and Measurements,  |c February 20, 2021 
300 |a 1 online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a NCRP commentary ;  |v no. 31 
504 |a Includes bibliographical references. 
505 0 |a Structure and Functions of the Brain -- How Radionuclides Enter the Brain -- Illustrations of Available Biokinetic Data for Brain -- Case Studies of the Effect of Explicit Modeling of Brain Kinetics on Dose Estimates for Internal Emitters -- Potential Improvements in Dosimetric Models of the Brain for Internal Emitters. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a "This Commentary examines current information on the accumulation, distribution, and retention of radionuclides in the brain and the extent to which that information can be used to improve estimates of dose to potentially radiosensitive regions of the brain from internal emitters, with emphasis on high linear-energy transfer (LET) alpha particle-emitting radionuclides. Dose estimates for the brain based on explicit brain models reflecting best available biokinetic data are compared with estimates based on the brain models typically used in radiation protection and dose reconstruction. The comparisons indicate that predictions of brain doses based on current models for radionuclides may substantially underestimate or overestimate brain dose projections based on an explicit brain model reflecting best available biokinetic data. Potential improvements in dose estimates for the brain based on more detailed dosimetric models of the brain are also examined. Improved estimates of radiation doses to brain based on more realistic biokinetic and dosimetric representations of the brain would be an important step forward in ongoing epidemiologic research aimed at evaluating dementia, Alzheimer's, Parkinson's, motor neuron diseases and cognitive impairment as possible adverse effects of radionuclide depositions in the brain"--  |c Provided by publisher. 
590 |a Knovel  |b Knovel (All titles) 
650 0 |a Brain  |x radiation effects. 
650 0 |a Radioisotopes  |x administration & dosage. 
650 0 |a Radiation  |x Measurement. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
710 2 |a National Council on Radiation Protection and Measurements,  |e editor. 
776 0 8 |i Print version:  |t Development of kinetic and anatomical models for brain dosimetry for internally deposited radionucldies  |d Bethesda, Maryland : National Council on Radiation Protection and Measurements, February 20, 2021  |z 9781944888282  |w (DLC) 2021060523 
830 0 |a NCRP commentary ;  |v no. 31. 
856 4 0 |u https://proxy.k.utb.cz/login?url=https://app.knovel.com/hotlink/toc/id:kpNCRPCND8/ncrp-commentary-no?kpromoter=marc  |y Full text 

Similar Items