Organometallic chemistry in industry : a practical approach

"Showcases the important role of organometallic chemistry in industrial applications and includes practical examples and case studies This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-wo...

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Bibliographic Details
Other Authors Colacot, Thomas (Editor), Seechurn, Carin C. C. Johansson (Editor), Grubbs, Robert H. (writer of foreword.)
Format Electronic eBook
LanguageEnglish
Published Weinheim : Wiley-VCH, [2020]
Subjects
Online AccessFull text
ISBN9783527819201
3527819207
9783527819195
3527819193
9783527819171
3527819177
9783527345175
3527345175
Physical Description1 online resource (338 pages) : illustrations

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Summary:"Showcases the important role of organometallic chemistry in industrial applications and includes practical examples and case studies This comprehensive book takes a practical approach to how organometallic chemistry is being used in industrial applications. It uniquely offers numerous, real-world examples and case studies that aid working R & D researchers as well as Ph. D. and postdoc students preparing to ace interviews in order to enter the workforce. Edited by two world-leading and established industrial chemists, the book covers flow chemistry (catalytic and non-catalytic organometallic chemistry), various cross-coupling reactions (C-C, C-N, and C-B) in classical batch chemistry, conjugate addition reactions, metathesis, and C-H arylation and achiral hydrogenation reactions. Beginning with an overview of the many industrial milestones within the field over the years, Organometallic Chemistry in Industry: A Practical Approach provides chapters covering: the design, development, and execution of a continuous flow enabled API manufacturing route; continuous manufacturing as an enabling technology for low temperature organometallic chemistry; the development of a nickel-catalyzed enantioselective Mizoroki-Heck coupling; and the development of iron-catalyzed Kumada cross-coupling for the large scale production of Aliskiren intermediates."--
Item Description:3.5.1 Manufacture of Verubecestat (MK-8931)
Bibliography:Includes bibliographical references and index.
ISBN:9783527819201
3527819207
9783527819195
3527819193
9783527819171
3527819177
9783527345175
3527345175
Access:Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty
Physical Description:1 online resource (338 pages) : illustrations