Biodegradable thermogels
Biodegradable thermogels are a promising class of stimuli-responsive polymers. This book summarizes recent developments in thermogel research with a focus on synthesis and self-assembly mechanisms, gel biodegradability, and applications for drug delivery, cell encapsulation and tissue engineering.
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| Other Authors | , |
|---|---|
| Format | Electronic eBook |
| Language | English |
| Published |
London :
Royal Society of Chemistry,
[2019]
|
| Series | Biomaterials science series ;
no. 2. |
| Subjects | |
| Online Access | Full text |
| ISBN | 9781788012676 1788012674 9781523122967 152312296X 9781782629405 1782629408 |
| ISSN | 2397-141X ; |
| Physical Description | 1 online resource : illustrations |
Cover
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| 245 | 0 | 0 | |a Biodegradable thermogels / |c edited by Xian Jun Loh and David James Young. |
| 264 | 1 | |a London : |b Royal Society of Chemistry, |c [2019] | |
| 300 | |a 1 online resource : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Biomaterials science series, |x 2397-141X ; |v no. 2 | |
| 505 | 0 | |a Cover; Preface; Contents; Chapter 1 Thermogelling Polymers and Their History; 1.1 Introduction; 1.2 Synthesis; 1.3 Micellization and Thermogelling Properties; 1.3.1 Gelation Mechanism; 1.3.2 Kinetics of Micellization; 1.3.3 Formation of Micelles with Different Morphologies; 1.4 Pluronic Systems in the Biomedical Sciences; 1.4.1 Early Uses; 1.4.2 Wound Healing; 1.4.3 Drug Delivery; 1.5 Disadvantages of Pluronic Systems; 1.6 Modifications of Pluronic Copolymers; 1.6.1 Modified Pluronic Copolymers for Improved Mechanical Properties. | |
| 505 | 8 | |a 1.6.2 Modified Pluronic Copolymers for Improved Biodegradability1.7 Modern Applications of Pluronics; 1.8 Future Perspectives; References; Chapter 2 Thermogelling PLGA-based Copolymers; 2.1 History and Structures; 2.2 Synthesis; 2.3 Properties; 2.3.1 Reversible Sol-to-gel Transition; 2.3.2 Degradation; 2.3.3 Biocompatibility; 2.4 Applications; 2.4.1 Drug Release; 2.4.2 Gene Delivery; 2.4.3 Postoperative Adhesion Prevention; 2.5 Areas for Future Research; 2.6 Conclusions; References. | |
| 505 | 8 | |a Chapter 3 Polyester-based Biodegradable Thermogelling Systems as Emerging Materials for Therapeutic Applications3.1 Introduction; 3.2 Polyester-based Thermogelling Systems; 3.2.1 The Poly(lactic acid)-based Thermogelling Systems; 3.2.2 Polycaprolactone-based Thermogelling Systems; 3.2.3 Poly([R]-3-hydroxybutyrate)-based Thermogelling System; 3.2.4 Poly(glycerol sebacate)-based Thermogelling Systems; 3.3 Application of Polyester-based Thermogelling Systems; 3.3.1 Therapeutic Delivery; 3.3.2 Tissue Engineering; 3.4 Conclusion; Abbreviations; References. | |
| 505 | 8 | |a Chapter 4 Biodegradable Thermogelling Polymers for Drug Delivery4.1 Introduction; 4.2 Thermogelling Mechanism; 4.3 Mechanism of Drug Release in Thermogels; 4.4 Advantages and Disadvantages of Thermogelling Polymeric Materials Compared to Other Drug-delivery Methods; 4.5 Delivery of Insulin and Protein Drugs in the Treatment of Diabetes; 4.6 Adaptation of Thermogels for Biomedical Applications; 4.6.1 Selenium-containing Thermogels; 4.6.2 Matrix Metalloproteinase-sensitive Thermogelling Polymers; 4.7 Towards Understanding In-vivo Effectiveness of Polymeric Thermogel Drug Delivery. | |
| 505 | 8 | |a 4.7.1 Toxicological Aspects of the Use of Dextran Microspheres and Thermogelling Ethyl(hydroxyethyl) Cellulose as Nasal Drug-delivery Systems4.7.2 In-vivo Pharmacological Evaluations of an Antioxidant-loaded Biodegradable Thermogel; 4.8 Conclusion; References; Chapter 5 Injectable Thermogelling Polymers for Bone and Cartilage Tissue Engineering; 5.1 Introduction; 5.2 Scaffold Requirements for Bone and Cartilage Tissue Engineering; 5.3 Chemistry and Properties of Selected Injectable Thermogelling Scaffolds; 5.3.1 Totally Non-degradable Polymers; 5.3.2 Enzymatically Degradable Polymers. | |
| 506 | |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty | ||
| 520 | |a Biodegradable thermogels are a promising class of stimuli-responsive polymers. This book summarizes recent developments in thermogel research with a focus on synthesis and self-assembly mechanisms, gel biodegradability, and applications for drug delivery, cell encapsulation and tissue engineering. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 590 | |a Knovel |b Knovel (All titles) | ||
| 650 | 0 | |a Polymers in medicine. | |
| 650 | 0 | |a Polymers |x Biotechnology. | |
| 655 | 7 | |a elektronické knihy |7 fd186907 |2 czenas | |
| 655 | 9 | |a electronic books |2 eczenas | |
| 700 | 1 | |a Loh, Xian Jun, |e editor. | |
| 700 | 1 | |a Young, David James, |e editor. | |
| 776 | 0 | 8 | |i Print version: |z 1782629408 |z 9781782629405 |w (OCoLC)1036275771 |
| 830 | 0 | |a Biomaterials science series ; |v no. 2. | |
| 856 | 4 | 0 | |u https://proxy.k.utb.cz/login?url=https://app.knovel.com/hotlink/toc/id:kpBT000003/biodegradable-thermogels?kpromoter=marc |y Full text |