Modern biocatalysis : advances towards synthetic biological systems

With contributions from leading academics around the world, this book makes a ground-breaking contribution to the field of biocatalysis and is essential reading for graduates and researchers investigating (bio)catalysis, enzyme engineering, chemical biology, and synthetic biology.

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Bibliographic Details
Other Authors: Williams, Gavin (Professor of chemistry), (Editor), Hall, Mélanie, (Editor)
Format: eBook
Language: English
Published: Cambridge : Royal Society of Chemistry, 2018
Series: RSC catalysis series ; no. 32.
Subjects:
Biocatalysis.
elektronické knihy
electronic books
ISBN: 9781788010450
1788010450
9781788014533
1788014537
9781523119431
1523119438
9781782627265
178262726X
Physical Description: 1 online resource (574 pages)

Cover

Table of contents

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245 0 0 |a Modern biocatalysis :  |b advances towards synthetic biological systems /  |c editors: Gavin Williams, Mélanie Hall. 
264 1 |a Cambridge :  |b Royal Society of Chemistry,  |c 2018 
300 |a 1 online resource (574 pages) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a RSC catalysis series ;  |v 32 
500 |a Includes index. 
500 |a Title from title details screen. 
505 0 |a Cover; Preface; Contents; Section I: Accessing New Enzymes; Chapter 1 Genome Mining for Enzyme Discovery; 1.1 Introduction; 1.2 Text-based Searches Using Enzyme Name; 1.3 Sequence-driven Approaches; 1.3.1 Probe Technology Based on PCR Primer Design; 1.3.2 Pairwise Sequence Alignment-based Strategy; 1.3.3 Signature-/Key Motif-based Strategy; 1.4 3D Structure-guided Approach; 1.4.1 Exploring 3D Structures of Proteins; 1.4.2 Active Site Topology/Constellation-guided Strategy; 1.5 Conclusion; References; Chapter 2 Exploiting Natural Diversity for Industrial Enzymatic Applications 
505 8 |a 2.1 Introduction2.2 Screening Enzymes from Soil Microbes, Plants, and Animals (Millipede) by Activity Measurement; 2.2.1 Hydrolases; 2.2.2 Oxidoreductases; 2.2.3 Lyases; 2.3 Genetic Approaches to Natural Enzyme Sources; 2.3.1 Isomerases; 2.3.2 Oxidoreductases; 2.4 Creation of Amine Oxidase by Directed Evolution of D-Amino Acid Oxidase; 2.5 From Discovery to Application -- Aldoxime Dehydratases; 2.5.1 Isolation, Characterization and Comparison of Aldoxime Dehydratases; 2.5.2 Iron Heme Redox Catalysis and Mechanistic Studies; 2.5.3 Substrate Spectrum of Aldoxime Dehydratases 
505 8 |a 2.5.4 Application of Oxds for Nitrile Synthesis2.5.5 Perspectives; 2.6 Conclusion; Acknowledgements; References; Chapter 3 Artificial Metalloenzymes; 3.1 Introduction; 3.2 Direct Insertion of Inorganic Metal Ions into Proteins; 3.2.1 Carbonic Anhydrase; 3.2.2 Ferritin; 3.2.3 Serum Albumins; 3.2.4 Phytase and Other Proteins; 3.3 Supramolecular Anchoring of Metal Cofactors; 3.3.1 The ""Trojan-Horse"" Strategy; 3.3.2 The ""Host-Guest"" Strategy; 3.4 Covalent Linking of Metallic Cofactors to a Protein; 3.5 Cascade Reactions; 3.6 Conclusion; References 
505 8 |a Chapter 4 Computational Enzyme Design: Successes, Challenges, and Future Directions4.1 Introduction; 4.2 Examples of Computational Enzyme Design; 4.2.1 Phase I: Initial Application of CPD Towards Enzyme Design; 4.2.2 Phase II: Incorporation of TransitionStates and Theozymes into Computational Enzyme Design; 4.3 Challenges in Computational Enzyme Design; 4.4 Future Directions; 4.5 Conclusions; Acknowledgements; References; Section II: Understanding and Engineering Enzymes; Chapter 5 Computational Techniques for Efficient Biocatalysis; 5.1 Introduction to Computational Biocatalysis 
505 8 |a 5.1.1 Bioinformatic Tools5.1.2 Ancestral Gene Resurrection; 5.1.3 Structure-based Computational Tools; 5.1.4 QM Computational Tools; 5.1.5 Molecular Mechanics and Molecular Dynamics Computational Tools; 5.1.6 QM/MM; 5.2 Implementation of Computational Tools in Biocatalysis; 5.2.1 Identification of Novel Biocatalysts from Sequence Space; 5.2.2 Ancestral Enzyme Reconstruction for the Study and Engineering of Binding and Catalysis; 5.3 Structural-based In Silico Modelling for Efficient Biocatalysis 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a With contributions from leading academics around the world, this book makes a ground-breaking contribution to the field of biocatalysis and is essential reading for graduates and researchers investigating (bio)catalysis, enzyme engineering, chemical biology, and synthetic biology. 
590 |a Knovel  |b Knovel (All titles) 
650 0 |a Biocatalysis. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Williams, Gavin  |c (Professor of chemistry),  |e editor.  |1 https://id.oclc.org/worldcat/entity/E39PCjqDFqBr6kGXRpTwmWw6cd 
700 1 |a Hall, Mélanie,  |e editor. 
776 0 8 |i Print version:  |z 9781782627265 
830 0 |a RSC catalysis series ;  |v no. 32. 
856 4 0 |u https://proxy.k.utb.cz/login?url=https://app.knovel.com/hotlink/toc/id:kpMBASBS02/modern-biocatalysis-advances?kpromoter=marc  |y Full text 

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