Nanobiomaterials : nanostructured materials for biomedical applications
Saved in:
| Other Authors | |
|---|---|
| Format | Electronic eBook |
| Language | English |
| Published |
Duxford, United Kingdom :
Woodhead Publishing,
[2018]
|
| Edition | First edition. |
| Series | Woodhead Publishing series in biomaterials.
|
| Subjects | |
| Online Access | Full text |
| ISBN | 9780081007259 0081007256 0081007167 9780081007167 |
| Physical Description | 1 online resource : illustrations |
Cover
Table of Contents:
- Front Cover
- Nanobiomaterials: Nanostructured Materials for Biomedical Applications
- Copyright
- Contents
- List of contributors
- Chapter 1: Nanostructured ceramics
- 1.1 Introduction
- 1.2 Test methods for nanostructured ceramics
- 1.2.1 Micro/nanostructural evaluation
- 1.3 Nanostructured bioceramics
- 1.3.1 Low temperature chemical bonding
- 1.3.2 Why nanostructures in chemically bonded ceramics?
- 1.3.3 Nanostructures in the Ca-aluminate-Ca-phosphate system (CAPH)
- 1.4 Application field of nanostructured bioceramics
- 1.4.1 Dental applications including coating products
- 1.4.2 Orthopedic applications
- 1.4.3 Drug delivery carrier applications
- 1.5 Conclusion and summary
- Acknowledgement
- References
- Chapter 2: Bio-based nanostructured materials
- 2.1 Introduction
- 2.2 Polysaccharide-based nanomaterials
- 2.2.1 Chitin
- 2.2.2 Chitosan
- 2.2.3 Cellulose
- 2.3 Carbon
- 2.4 Clay
- 2.5 Plant proteins
- 2.6 Keratin
- 2.7 Phage
- 2.8 Natural bioceramics
- 2.9 Conclusion and future trends
- References
- Chapter 3: Self-assembled nanomaterials
- 3.1 Introduction
- 3.2 Why self-assembled nanomaterials?
- 3.3 Polymer-based self-assembled carriers
- 3.3.1 Polymeric nanoparticles
- 3.3.1.1 Nanospheres
- 3.3.1.2 Nanocapsules
- 3.3.1.3 Nanogels
- 3.3.1.4 Polymeric micelles
- 3.3.1.5 Polymersomes
- 3.3.1.6 Liquid crystals
- 3.3.1.7 Dendrimers
- 3.4 Lipid-based self-assembled carriers
- 3.4.1 Liposomes
- 3.4.2 Solid lipid nanoparticles
- 3.4.3 Lipid nanocapsules
- 3.4.4 Microemulsions
- 3.4.5 Self-microemulsifing drug delivery systems
- 3.5 Concluding remarks and future perspectives
- References
- Chapter 4: Nanowires for biomedical applications
- 4.1 Introduction
- 4.2 Fabrication
- 4.3 Biocompatibility
- 4.4 Application
- 4.4.1 Neural interface
- 4.4.2 Tissue engineering.
- 4.4.3 Force sensing
- References
- Further reading
- Chapter 5: [60]Fullerene and derivatives for biomedical applications
- 5.1 Introduction
- 5.2 Physicochemical properties
- 5.3 Physical properties responsible of the main biological effects
- 5.3.1 Shape and size
- 5.3.2 Singlet oxygen (1O2) formation
- 5.3.3 Free-radical scavenging
- 5.4 Potential biomedical applications
- 5.4.1 Enzyme inhibition
- 5.4.2 Imaging and radiotherapy
- 5.4.3 Photodynamic therapy
- 5.4.4 Free-radical scavenging
- 5.4.5 Miscellaneous
- 5.5 Toxicity, pharmacokinetics, metabolism, and excretion
- 5.5.1 Toxicity
- 5.5.1.1 Toxicity studies on pristine C60
- 5.5.1.2 Toxicity of noncovalently modified C60
- 5.5.1.3 Toxicity of covalently modified C60
- 5.5.2 Pharmacokinetics, metabolism and excretion
- 5.5.2.1 Studies on unmodified C60
- 5.5.2.2 Studies on C60 derivatives
- 5.6 Conclusion
- References
- Further reading
- Chapter 6: Self-assembled monolayers in biomaterials
- 6.1 Introduction
- 6.1.1 Scope of this chapter
- 6.2 Self-assembled monolayers
- 6.2.1 Chemical modification of gold surfaces by the SAMs
- 6.2.1.1 SAMs preparation and structure
- 6.2.1.2 Kinetic studies of the SAM formation
- 6.2.1.3 Single/mono and mixed SAMs
- 6.2.1.4 Factors governing the formation of SAMs
- 6.2.1.5 Characterization of the SAMs
- 6.2.1.6 Effect of alkanethiols SAMs on protein adsorption and cell behavior
- 6.2.2 Organosilane-based SAMs on silicon surfaces
- 6.2.2.1 Factors affecting the formation of organosilane SAMs
- Water
- Temperature
- Solvent
- 6.2.2.2 Interface properties: wettability, surface tension, topography and potential
- 6.2.2.3 Modifications of SAMs and patterning
- Click chemistry
- Nucleophilic substitution
- Supramolecular modification
- SAMs patterning
- 6.2.2.4 Biomolecules' behavior on silane SAMs-modified surfaces.
- Protein adsorption
- Cell adhesion
- 6.2.3 SAMs based on long polymers
- 6.2.3.1 Polymeric SAMs
- Biomolecules at polymer brushes
- 6.3 Conclusion
- References
- Chapter 7: Nanostructured surfaces in biomaterials
- 7.1 Introduction
- 7.2 Surface modification methods of titanium
- 7.3 Bulk nanostructured titanium
- 7.4 Bulk titanium-bioceramic nanocomposites
- 7.5 Nanostructured surfaces
- 7.6 Antibacterial activity of nanostructured Ti-45S5 Bioglass-Ag composite
- 7.7 Conclusion
- References
- Chapter 8: Magnetic nanoparticle synthesis
- 8.1 Introduction
- 8.2 Production of magnetic nanoparticles
- 8.2.1 Mechanical milling
- 8.2.2 Co-precipitation
- 8.2.3 Nanoreactors/microemulson techniques
- 8.2.4 Sonochemical processing
- 8.2.5 Sol-gel methods
- 8.2.6 Flow injection
- 8.2.7 Electrochemical production
- 8.2.8 Supercritical fluid techniques
- 8.2.9 Thermal decomposition
- 8.2.10 Hydrothermal routes
- 8.2.11 Microwave techniques
- 8.2.12 Spray pyrolysis
- 8.2.13 Laser pyrolysis
- 8.2.14 Flame spray pyrolysis
- 8.2.15 Gas phase synthesis
- 8.2.16 Arc discharge
- 8.2.17 Oxidation
- 8.2.18 Microbial methods
- 8.3 Stabilization/coating methods
- 8.3.1 Polymers
- 8.3.2 Precious metals
- 8.3.3 Silica
- 8.3.4 Carbon
- 8.3.5 Oxidation
- 8.3.6 Physical encapsulation
- 8.4 Conclusions
- References
- Further reading
- Chapter 9: Toxicity of nanostructured biomaterials
- 9.1 Nanotoxicology: Concepts and claims
- 9.2 Dose and dosimetry of nanobiomaterials
- 9.3 Surface topography of nanobiomaterials and associated surface reactivity
- 9.4 NPs and the environment
- 9.5 Interfaces between nanobiomaterials and target cells
- 9.6 Routes of entry of nanobiomaterials
- 9.7 Effect of nanobiomaterials on biomolecules
- 9.8 Nanobiomaterials and their effect on DNA.
- 9.9 In vivo toxicology of nanobiomaterials in humans: Prospective mechanisms
- 9.10 Toxicity of different nanostructured biomaterials
- 9.10.1 Gold NPs
- 9.10.2 Silver NPs
- 9.10.3 Silica NPs
- 9.10.4 Selenium NPs
- 9.10.5 Titanium dioxide NPs
- 9.10.6 Zinc oxide NPs
- 9.10.7 Cerium oxide NPs
- 9.10.8 Polymeric NPs
- 9.10.9 Carbonaceous NPs
- 9.10.9.1 Carbon nanotubes
- 9.10.9.2 Graphene
- 9.11 Future scope and conclusion
- Acknowledgments
- References
- Chapter 10: Use of nanostructured materials in hard tissue engineering
- 10.1 Introduction
- 10.2 The intricacies of hard tissue architecture and engineering considerations
- 10.2.1 Hard tissue cellular composition
- 10.2.2 Composition of hard tissue extracellular matrix
- 10.2.3 Considerations for intelligence in biomimicry of the extracellular matrix for a rational approach to hard tiss ...
- 10.3 Fabrication approaches for designing nanostructured materials for hard tissue engineering
- 10.4 Integration of diverse approaches and biomaterials for the design of nanostructured material scaffolds for bone ...
- 10.4.1 Electrospun nanofiber-based scaffolds
- 10.4.2 Nanofiber-based scaffolds via thermally induced phase separation
- 10.4.3 Nanocrystalline hydroxyapatite-based scaffolds via combinatory lyophilization approaches
- 10.4.4 Bioactive glass-based nanostructured composites via the sol-gel process
- 10.4.5 Magnetically synthesized carbon nanotube-structured scaffolds via lyophilization
- 10.4.6 Nanodiamond-structured scaffolds via solvent evaporation/solvent casting
- 10.4.7 Magnetic nanoparticle-structured biomimetic scaffolds
- 10.4.8 Nanostructured scaffolds via rapid prototyping technologies
- 10.5 Integration of diverse approaches and biomaterials for the design of nanostructured material scaffolds for denta ...
- 10.5.1 Nanostructured materials for enamel regeneration
- 10.5.2 Nanostructured materials for pulpodentinal complex regeneration
- 10.5.3 Nanostructured materials for periodontal apparatus regeneration
- 10.5.4 Nanostructured materials for whole tooth regeneration
- 10.6 Conclusions, challenges, and proposed future advances for nanostructured materials in hard tissue engineering
- References
- Chapter 11: Nanobiomaterials in dentistry
- 11.1 Introduction to nanotechnology in dentistry
- 11.1.1 Definition
- 11.1.2 Types
- 11.1.3 Applications of nanotechnology
- 11.2 Nanotechnology in dentistry
- 11.2.1 Research
- 11.2.1.1 Tissue engineering and stem cells
- 11.2.2 Preventive dentistry
- 11.2.2.1 Decontamination, disinfection, and sterilization
- 11.2.2.2 Toothpaste and mouthwash
- 11.2.2.3 Caries prevention
- 11.2.3 Conservative dentistry and prosthodontics
- 11.2.3.1 Introduction to anesthetics
- 11.2.3.2 Bonding materials
- 11.2.3.3 Impression materials
- 11.2.3.4 New composite materials
- 11.2.4 Periodontics, oral surgery and implants
- 11.2.4.1 Early disease diagnosis
- 11.2.4.2 Oral cancer diagnosis and treatment
- 11.2.4.3 Needles in cell surgery
- 11.2.4.4 Tissue regeneration
- 11.2.4.5 Acceleration of the healing process
- 11.2.4.6 Dental implant surfaces
- Bone-implant interface
- 11.2.5 Orthodontics
- 11.2.5.1 Reduction of orthodontic forces
- 11.2.5.2 Bonding properties
- 11.2.5.3 Antibacterial and anticarious properties
- 11.2.5.4 Orthodontic treatment time reduction
- 11.3 Discussion and conclusions
- 11.3.1 Problems and advantages
- References
- Further reading
- Chapter 12: Use of nanostructured materials in medical diagnostics
- 12.1 Zero-dimensional (0-D) nanostructured materials
- 12.1.1 Introduction
- 12.1.2 Synthesis
- 12.1.3 Property.