Practical methods for biocatalysis and biotransformations 3

• Other Authors: Whittall, John (Editor), Sutton, Peter (Editor), Kroutil, Wolfgang, 1972- (Editor)
• Format: Electronic eBook
• Language: English
• Published: Chichester, West Sussex : John Wiley & Sons, Ltd., 2016.
• Edition: 3.
• Subjects: Enzymes > Biotechnology.; Biocatalysis.; Biotransformation (Metabolism); Organic compounds > Synthesis.; elektronické knihy; electronic books
• ISBN: 9781523114719; 1523114711; 9781118696286; 111869628X; 9781118696293; 1118696298; 9781118697856; 1118697855; 111860525X; 9781118605257
• Physical Description: 1 online resource

Table of Contents:

• Practical Methods for Biocatalysis and Biotransformations 3; Contents; List of Contributors; Abbreviations; Chapter 1: Considerations for the Application of Process Technologies in Laboratory- and Pilot-Scale Biocatalysis for Chemical Synthesis; 1.1 Introduction; 1.2 Process Intensification and Proposed Scale-Up Concept; 1.3 Enabling Technologies; 1.3.1 Biocatalyst Immobilization; 1.3.1.1 General Considerations for Implementation; 1.3.1.2 Carrier-Bound Supported Enzymes; 1.3.1.2.1 Adsorption; Considerations for Implementation; 1.3.1.2.2 Covalent Binding; Considerations for Implementation.
• 1.3.1.2.3 Ionic BindingConsiderations for Implementation; 1.3.1.3 Carrier-Free Immobilization; 1.3.1.3.1 Cross-Linked Enzyme Aggregates (CLEAsTM); Considerations for Implementation; 1.3.2 Reactor Options; 1.3.2.1 Ideal Reactors; 1.3.2.2 Modes of Operation; 1.3.2.3 Well-Mixed Reactor Hydrodynamics; 1.3.2.3.1 Stirred Tanks; Considerations for Implementation; 1.3.2.3.2 Batch Stirred-Tank Reactors (BSTRs); Considerations for Implementation; 1.3.2.3.3 Continuous Stirred-Tank Reactors (CSTRs); Considerations for Implementation; 1.3.2.3.4 Alternative Well-Mixed Reactors.
• Continuous Fluidized-Bed Reactors (CFBRs)Considerations for Implementation; Continuous Packed-Bed Reactors (CPBRs); Considerations for Implementation; Continuous Expanded-Bed Reactors (CEBRs); Considerations for Implementation; 1.3.2.3.5 Membrane Bioreactors (MBRs); Considerations for Implementation; 1.4 Enhancing Technologies; 1.4.1 In Situ Product Removal (ISPR); 1.4.1.1 Considerations for Implementation; 1.4.1.2 ISPR by Adsorption on Resins; 1.4.1.2.1 Considerations for Implementation; 1.4.1.3 ISPR Using Expanded-Bed Adsorption (EBA); 1.4.1.3.1 Considerations for Implementation.
• 1.4.1.4 ISPR by Crystallization1.4.1.4.1 Considerations for Implementation; 1.4.2 Substrate Feeding Strategies; 1.4.2.1 Fed-Batch Operation; 1.4.2.1.1 Considerations for Implementation; 1.4.3 Non-Conventional Media; 1.4.3.1 Single Non-Conventional Liquid Phase Systems; 1.4.3.1.1 Considerations for Implementation; 1.4.3.2 Aqueous-Organic Two-Liquid Phase Systems; 1.4.3.2.1 Considerations for Implementation; 1.4.3.3 Aqueous-Ionic Liquid Two-Liquid Phase Systems; 1.4.3.3.1 Considerations for Implementation; 1.4.4 Oxygen Supply Strategies; 1.4.4.1 Surface Aeration.
• 1.4.4.1.1 Considerations for Implementation1.4.4.2 Sparged Aeration; 1.4.4.2.1 Considerations for Implementation; 1.4.4.3 Bubble-Column Reactors; 1.4.4.3.1 Considerations for Implementation; 1.5 Conclusion; References; Chapter 2: Cytochrome P450 (CYP) Progress in Biocatalysis for Synthetic Organic Chemistry; 2.1 Introduction; 2.2 CYP Development; 2.3 Recent Developments; 2.4 Conclusion; References; Chapter 3: Use of Hydrolases and Related Enzymes for Synthesis; 3.1 Continuous-Flow Reactor-Based Enzymatic Synthesis of Phosphorylated Compounds on a Large Scale; 3.1.1 Materials and Equipment.