Translational medicine and drug discovery
"This book, edited by two leaders known for driving innovation in the field, focuses on the new discipline of translational medicine as it pertains to drug discovery and development within the pharmaceutical and biotechnology industries. Translational medicine seeks to translate biological and...
Saved in:
| Other Authors: | , |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
Cambridge :
Cambridge University Press,
2011.
|
| Subjects: | |
| ISBN: | 9781139127035 1139127039 9781139109840 1139109847 9780511976087 0511976089 9781139114202 1139114204 9781139116374 1139116371 9780521886451 0521886457 9781107435940 1107435943 1283295563 9781283295567 1139122118 9781139122115 9786613295569 6613295566 1139112015 9781139112017 |
| Physical Description: | 1 online resource (xx, 361 pages) : illustrations |
Cover
Table of contents
| LEADER | 06011cam a2200661 i 4500 | ||
|---|---|---|---|
| 001 | kn-ocn759114752 | ||
| 003 | OCoLC | ||
| 005 | 20240717213016.0 | ||
| 006 | m o d | ||
| 007 | cr cn||||||||| | ||
| 008 | 111031t20112011enka ob 001 0 eng d | ||
| 040 | |a N$T |b eng |e rda |e pn |c N$T |d CDX |d E7B |d YDXCP |d VRC |d KNOVL |d ZCU |d OCLCQ |d CAMBR |d RRP |d OL$ |d KNOVL |d FTU |d EBLCP |d MHW |d IDEBK |d AUD |d OCLCQ |d D6H |d OCLCQ |d OCLCO |d OCLCQ |d OCLCO |d MERER |d OCLCO |d OCLCQ |d OCLCO |d OCLCQ |d OCLCO |d OCLCA |d BUF |d OCLCO |d UAB |d UUM |d OCLCQ |d INT |d AU@ |d OCLCO |d OCLCQ |d OCLCO |d WYU |d OCLCQ |d OCLCA |d OCLCQ |d OCLCO |d OCLCF |d UKAHL |d OCLCQ |d OCLCA |d EUN |d OCLCO |d OCLCQ |d OCLCO |d OCLCL |d OCLCQ |d OCLCA |d OCLCL | ||
| 020 | |a 9781139127035 |q (electronic bk.) | ||
| 020 | |a 1139127039 |q (electronic bk.) | ||
| 020 | |a 9781139109840 |q (electronic bk.) | ||
| 020 | |a 1139109847 |q (electronic bk.) | ||
| 020 | |a 9780511976087 |q (electronic bk.) | ||
| 020 | |a 0511976089 |q (electronic bk.) | ||
| 020 | |a 9781139114202 |q (electronic bk.) | ||
| 020 | |a 1139114204 |q (electronic bk.) | ||
| 020 | |a 9781139116374 |q (electronic bk.) | ||
| 020 | |a 1139116371 |q (electronic bk.) | ||
| 020 | |z 9780521886451 |q (hardback) | ||
| 020 | |z 0521886457 |q (hardback) | ||
| 020 | |z 9781107435940 |q (paperback) | ||
| 020 | |z 1107435943 |q (paperback) | ||
| 020 | |a 1283295563 | ||
| 020 | |a 9781283295567 | ||
| 020 | |a 1139122118 | ||
| 020 | |a 9781139122115 | ||
| 020 | |a 9786613295569 | ||
| 020 | |a 6613295566 | ||
| 020 | |a 1139112015 | ||
| 020 | |a 9781139112017 | ||
| 024 | 8 | |a 9786613295569 | |
| 035 | |a (OCoLC)759114752 |z (OCoLC)759007132 |z (OCoLC)769341748 |z (OCoLC)781746819 |z (OCoLC)813436656 |z (OCoLC)846188811 |z (OCoLC)990595486 |z (OCoLC)1058089893 |z (OCoLC)1058845476 |z (OCoLC)1065925835 | ||
| 245 | 0 | 0 | |a Translational medicine and drug discovery / |c edited by Bruce H. Littman, Rajesh Krishna. |
| 264 | 1 | |a Cambridge : |b Cambridge University Press, |c 2011. | |
| 264 | 4 | |c ©2011 | |
| 300 | |a 1 online resource (xx, 361 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 506 | |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty | ||
| 520 | |a "This book, edited by two leaders known for driving innovation in the field, focuses on the new discipline of translational medicine as it pertains to drug discovery and development within the pharmaceutical and biotechnology industries. Translational medicine seeks to translate biological and molecular knowledge of disease and how drugs work into innovative strategies that reduce the cost and increase the speed of delivering newmedicines for patients. This book describes these general strategies, biomarker development, imaging tools, translational human models, and examples of their application to real-life drug discovery and development. The latest thinking is presented by researchers from many of the world's leading pharmaceutical companies, including Pfizer, Merck, Eli Lilly, Abbott, and Novartis, as well as from academic institutions and public-private partnerships that support translational research. This book is essential for anyone interested in translational medicine from a variety of backgrounds (university institutes, medical schools, and pharmaceutical companies) in addition to drug development researchers and decision makers."--Publisher's description. | ||
| 505 | 0 | 0 | |g SECTION I: |t Translational Medicine: History, Principles, and Application in Drug Development -- |g 1. |t Translational Medicine: Definition, History, and Strategies / |r Bruce H. Littman -- |g 2. |t Translational Medicine and Its Impact on Diabetes Drug Development / |r Roberto A. Calle and Ann E. Taylor -- |g 3. |t Challenges in Atherosclerosis / |r John S. Millar -- |g 4. |t Obesity: New Mechanisms and Translational Paradigms / |r Gregory Gaich and David E. Moller -- |g 5. |t Bone Disorders: Translational Medicine Case Studies / |r S. Aubrey Stoch -- |g 6. |t Case Studies in Neuroscience: Unique Challenges and Examples Gerard / |r J. Marek -- |g 7. |t Translational Medicine in Oncology / |r Dominic G. Spinella. |
| 505 | 8 | 0 | |g SECTION II: |t Biomarkers and Public-Private Partnerships -- |g 8. |t Biomarker Validation and Application in Early Drug Development: Idea to Proof of Concept / |r Pfizer Global Research and Development -- |g 9. |t Imaging Biomarkers in Drug Development: Case Studies / |r Johannes T. Tauscher and Adam J. Schwarz -- |g 10. |t European New Safe and Innovative Medicines Initiatives: History and Progress (through December 2009) / |r Ole J. Bjerrum and Hans H. Linden -- |g 11. |t Critical Path Institute and the Predictive Safety Testing Consortium / |r Elizabeth Gribble Walker -- |g 12. |t The Biomarkers Consortium: Facilitating the Development and Qualification of Novel Biomarkers Through a Precompetitive Public-Private Partnership / |r David Wholley and David B. Lee. |
| 505 | 8 | 0 | |g SECTION III: |t Future Directions -- |g 13. |t Improving the Quality and Productivity of Pharmacometric Modeling and Simulation Activities: the Foundation for Model-Based Drug Development / |r Thaddeus H. Grasela, Jill Fiedler-Kelly, and Robert Slusser -- |g 14. |t Embracing Change: a Pharmaceutical Industry Guide to the 21st Century / |r Mervyn Turner. |
| 590 | |a Knovel |b Knovel (All titles) | ||
| 650 | 0 | |a Drug development. | |
| 650 | 0 | |a Molecular pharmacology. | |
| 655 | 7 | |a elektronické knihy |7 fd186907 |2 czenas | |
| 655 | 9 | |a electronic books |2 eczenas | |
| 700 | 1 | |a Littman, Bruce H., |d 1944- |e editor. |1 https://id.oclc.org/worldcat/entity/E39PCjrPDyQPMRmgHdYj73By7d | |
| 700 | 1 | |a Krishna, Rajesh, |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Translational medicine and drug discovery. |d New York : Cambridge University Press, 2011 |z 9780521886451 |w (DLC) 2010037116 |w (OCoLC)660509871 |
| 856 | 4 | 0 | |u https://proxy.k.utb.cz/login?url=https://app.knovel.com/hotlink/toc/id:kpTMDD0001/translational-medicine-and?kpromoter=marc |y Full text |
Save to List
Cite this
Export Record
Email this