Sequence-specific DNA binding agents

The binding of antibiotics and drugs to DNA is a fast developing area of research with important applications in medicine, particularly the treatment of cancer. Sequence-specific DNA Binding Agents uniquely discusses key aspects of this topic, providing a novel perspective on the subject. Written by...

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Bibliographic Details
Other Authors: Waring, Michael J.
Format: eBook
Language: English
Published: Cambridge : RSC Pub., ©2006.
Series: RSC biomolecular sciences.
Subjects:
DNA-drug interactions.
DNA-binding proteins.
Gene targeting.
Drug targeting.
Chemotherapy.
elektronické knihy
electronic books
ISBN: 9781628701395
1628701390
1847555306
9781847555304
9780854043705
0854043705
Physical Description: 1 online resource (xi, 258 pages) : illustrations (some color)

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Table of contents

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020 |a 1628701390  |q (electronic bk.) 
020 |a 1847555306 
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020 |z 9780854043705 
020 |z 0854043705 
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042 |a dlr 
245 0 0 |a Sequence-specific DNA binding agents /  |c edited by Michael Waring. 
260 |a Cambridge :  |b RSC Pub.,  |c ©2006. 
300 |a 1 online resource (xi, 258 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a RSC biomolecular sciences 
504 |a Includes bibliographical references and index. 
505 0 |a DNA recognition by triple helix formation / David A. Rusling, Tom Brown, and Keith R. Fox -- Interfacial inhibitors of human topoisomerase I / Christophe Marchand and Yves Pommier -- Diversity of topoisomerase I inhibitors for cancer chemotherapy / Nathalie Dias and Christian Bailly -- Slow DNA binding / L. Marcus Wilhelmsson, Per Lincoln, and Bengt Nordén -- DNA gene targeting using Peptide Nucleic Acid (PNA) / Peter E. Nielsen -- Actinomycin D : sixty years of progress in characterizing a sequence-selective DNA-binding agent / David E. Graves -- Thermal denaturation of drug-DNA complexes : tools and tricks / Jonathan B. Chaires and Xiaochun Shi -- Computer simulations of drug-DNA interactions : a personal journey / Federico Gago -- The discovery of G-quadruplex telomere targeting drugs / Stephen Neidle -- The mechanism of action of telomestatin, a G-quadruplex-interactive compound / Daekyu Sun and Laurence H. Hurley -- Structural features of the specific interactions between nucleic acids and small organic molecules / Alexander Serganov and Dinshaw J. Patel. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a The binding of antibiotics and drugs to DNA is a fast developing area of research with important applications in medicine, particularly the treatment of cancer. Sequence-specific DNA Binding Agents uniquely discusses key aspects of this topic, providing a novel perspective on the subject. Written by experts in the field, this book discusses diverse modes of binding of antibiotics and drugs to DNA, emphasising matters that are important or promising for cancer treatment. Chapters discuss established agents like actinomycin D but also look at novel drugs with strong potential in chemotherapy suc. 
590 |a Knovel  |b Knovel (All titles) 
650 0 |a DNA-drug interactions. 
650 0 |a DNA-binding proteins. 
650 0 |a Gene targeting. 
650 0 |a Drug targeting. 
650 0 |a Chemotherapy. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Waring, Michael J. 
776 0 8 |i Print version:  |w (DLC) 2007360567  |w (OCoLC)72867758 
830 0 |a RSC biomolecular sciences. 
856 4 0 |u https://proxy.k.utb.cz/login?url=https://app.knovel.com/hotlink/toc/id:kpSSDNABA3/sequence-specific-dna?kpromoter=marc  |y Full text 

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