Signal transduction

Up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention * In-depth coverage of nuclear receptors, including steps in isolation of steriod hormones and the discovery of intracellular hormone receptors; Tyrosine protein kinases and adaptive immunity; and...

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Bibliographic Details
Main Author Gomperts, B. D.
Other Authors Tatham, Peter E. R. (Life scientist), Kramer, Ijsbrand M.
Format Electronic eBook
LanguageEnglish
Published Amsterdam ; Boston : Elsevier/Academic Press, ©2009.
Edition2nd ed.
Subjects
Cellular signal transduction.
elektronické knihy
electronic books
Online AccessFull text
Full text
ISBN9780080568775
0080568777
9780080919058
0080919057
9780123948199
0123948193
9780123694416
0123694418
9780123948038
0123948037
Physical Description1 online resource (xxvii, 810 pages) : color illustrations

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Table of Contents:
  • Prologue: Signal Transduction, origins and ancestors
  • First messengers
  • Receptors
  • GTP-binding proteins and signal transduction
  • Effector enzymes coupled to GTP binding proteins: adenylyl cyclase and phospholipase C
  • The regulation of visual transduction and olfaction
  • Intracellular calcium
  • Calcium effectors
  • Phosphorylation and dephosphorylation: protein kinases A and C
  • Nuclear receptors
  • Growth Factors: Setting the framework
  • Signalling pathways operated by receptor protein tyrosine kinases
  • Signal transduction to and from adhesion molecules
  • Adhesion molecules in the regulation of cell differentiation: Mainly about Wnt
  • Activation of the innate immune system: the Toll-like receptor 4 and Signalling through Ubiquitylation
  • Traffic of white blood cells
  • Tyrosine protein kinases and adaptive immunity : TCR, BCR, soluble tyrosine kinases and NFAT
  • Phosphoinositide 3-kinases, protein kinase B and signalling through the insulin receptor
  • Protein Kinase C revisited
  • Signalling through receptor serine/threonine kinases
  • Protein dephosphorylation and protein phosphorylation
  • Notch
  • Targeting transduction pathways for research and medical intervention
  • Protein domains and signal transduction.

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