Process chemistry in the pharmaceutical industry. Volume 2, Challenges in an ever changing climate /

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Bibliographic Details
Other Authors Gadamasetti, Kumar G., 1949-, Braish, Tamim
Format Electronic eBook
LanguageEnglish
Published Boca Raton : CRC Press, ©2008.
Subjects
Pharmaceutical chemistry.
Chemical processes.
elektronické knihy
electronic books
Online AccessFull text
ISBN9781420008357
1420008358
9781628705515
1628705515
0849390516
9780849390517
Physical Description1 online resource (xxviii, 480 pages) : illustrations (some color)

Cover

Table of Contents:
  • Process Chemistry in the Pharmaceutical Industry: Challenges in an Ever-Changing Climate--An Overview; K. Gadamasetti ; Emerging Trends in Process Chemistry; T.F. Braish, F. De Knaep, and K. Gadamasetti ; Varenicline: Discovery Synthesis and Process Chemistry Developments; J.W. Coe, H.A. Watson Jr., and R.A. Singer ; The SUTENT® Story; R. Vaidyanathan ; An Efficient and Scalable Process for the Preparation of a Potent MC4 Receptor Agonist; C. Savarin, J. Chung, J.A. Murry, R.J. Cvetovich, C. McWilliams, D. Hughes, J. Amato, G. Boice, K. Conrad, E. Corley, R. Reamer, and L. DiMichele ; Process Research and Development of LY414197, a 5HT2B Antagonist; A. Borghese and A. Merschaert ; To Overcome the Hurdles: Coping with the Synthesis of Robalzotan, a Complex Chroman Antidepressant; H.J. Federsel and A. Sveno ; Chiral Amine Synthesis--Strategies, Examples, and Limitations; T.C.
  • Nugent ; Unnatural Amino Acids; D.J. Ager ; The Chemical Development of a Potential Manufacturing Route to the Endothelin Antagonists UK-350, 926 and UK-349, 862; C.P. Ashcroft, S. Challenger, A.M. Derrick, Y. Hajikarimian, and N.M. Thomson ; Cefovecin Sodium: A Single-Dose Long-Acting Antibiotic for Use in Companion Animals; T. Norris ; The Lithium-Halogen Exchange Reaction in Process Chemistry; W.F. Bailey and T.L. Rathman ; Oxetan-3-one: Chemistry and Synthesis; G. Wuitschik, E.M. Carreira, M. Rogers-Evans, and K. Müller ; Well-Defined (NHC)Pd (II) Complexes and Their Use in C-C and C-N Bond-Forming Reactions; O. Navarro and S.P. Nolan ; Toward Truly Efficient Organic Reactions in Water; C. Ogawa and S. Kobayashi ; The Chemical Development of the Commercial Route to Sildenafil Citrate; P.J.
  • Dunn ; Stereoselective Enzymatic Synthesis of Intermediates Used for Antihypertensive, Antiinfective, and Anticancer Compounds; R.L. Hanson ; Designing Robust Crystallization Processes for Active Pharmaceutical Ingredients--From Art to Science; D. Wieckhusen ; In Situ Mid-Infrared Spectroscopy for Process Development; D.A. Conlon, W. Izzo, J. Christopher McWilliams, R.A. Reamer, F. Xu, and P. Collins ; Optimizing an Asymmetric Homologation in a Tandem Asymmetric Homologation-Homoaldol Reaction; J.C. McWilliams and R.A. Reamer ; Development of Efficient One-Pot Process in the Synthesis of Sitagliptin: Application of Online-Infrared for Kinetic Studies to Probe the Reaction Mechanism; F. Xu ; Mid-Infrared Monitoring Applications during Development of the Vinyl Ether Formation Step in the Preparation of Aprepitant (Emend®); D.A. Conlon, W. Izzo, and P.
  • Collins ; Process Analytical Technology in the Manufacture of Bulk Active Pharmaceuticals--Promise, Practice, and Challenges; C.A. Mojica and L. St. Pierre-Berry ; PEGylation of Biological Macromolecules; J.J. Buckley, R.F. Finn, J. Mo, L.A. Bass, and S.V. Ho ; Microwave Technology in Process Optimization; F. Mavandadi ; Process Development Considerations for Therapeutic Monoclonal Antibodies in Mammalian Cell Culture; S. Casnocha, R. Fedechko, P. Mensah, J. Mott, and S. Nema ; Reaction Progress Kinetic Analysis: A Powerful Methodology for Streamlining Pharmaceutical Reaction Steps; N. Zotova, S.P. Mathew, H. Iwamura, and D.G. Blackmond ; Trends in Outsourcing; J. Lu and I. Shinkai ; Sourcing Pharmaceutical Products in China and India; D. Robins and S. Hannon Index

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