Handbook of pharmaceutical analysis by HPLC

High pressure liquid chromatography & ndash;frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the...

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Bibliographic Details
Other Authors Ahuja, Satinder, 1933-, Dong, M. W.
Format Electronic eBook
LanguageEnglish
Published Amsterdam ; Boston : Elsevier Academic Press, 2005.
Edition1st ed.
SeriesSeparation science and technology (San Diego, Calif.) ; v. 6.
Subjects
Online AccessFull text
ISBN0080455182
9780080455181
1280630574
9781280630576
9786610630578
6610630577
9780120885473
0120885476
Physical Description1 online resource (xix, 658 pages) : illustrations

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Table of Contents:
  • Overview.
  • Key concepts of HPLC in pharmaceutical analysis.
  • HPLC instrumentation: in pharmaceutical analysis: status, advances and trends.
  • HPLC columns for pharmaceutical.
  • Sample preparation for HPLC analysis of drug products.
  • HPLC method development.
  • Validation of HPLC methods in pharmaceutical analysis.
  • Ion Chromatography.
  • How to be more successful with HPLC analysis:: practical aspects in HPLC operation.
  • Regulatory considerations in HPLC anaysis.
  • HPLC system calibration for GMP compliance.
  • System validation: pre-installation, IQ, OQ and PQ.
  • Assays and stability testing.
  • Impurity evaluation.
  • HPLC in dissolution testing.
  • Cleaning validation using HPCL for analysis.
  • LC/MS application in high throughput ADME screen.
  • Chiral separations.
  • Applications of LC/MS in pharmaceutical analysis.
  • Application of LC-MMR in Pharmaceutical Analysis.
  • Chromatography data systems (CDS) in the pharmaceutical laboratory; its history, advances and future direction.
  • New developments in HPLC.