Extrapolation of radiation-induced cancer risks from nonhuman experimental systems to humans.

Saved in:
Bibliographic Details
Corporate Author: National Council on Radiation Protection and Measurements.
Format: eBook
Language: English
Published: Bethesda, MD : National Council on Radiation Protection and Measurements, ©2005.
Series: NCRP report ; no. 150.
Subjects:
Radiation carcinogenesis.
Radiation > Toxicology.
Animal models in research.
Carcinogenicity testing.
Diseases > Animal models.
elektronické knihy
electronic books
ISBN: 9781601192134
1601192134
9781429479967
1429479965
092960086X
9780929600864
Physical Description: 1 online resource (xii, 267 pages) : illustrations

Cover

Table of contents

LEADER 05339cam a2200541 a 4500
001 kn-ocn123432930
003 OCoLC
005 20240717213016.0
006 m o d
007 cr cn|||||||||
008 070424s2005 mdua ob 001 0 eng d
040 |a KNOVL  |b eng  |e pn  |c KNOVL  |d OCLCQ  |d KNOVL  |d OCLCO  |d ZCU  |d KNOVL  |d OCLCF  |d OCLCE  |d KNOVL  |d OCLCQ  |d BUF  |d COCUF  |d N$T  |d YDXCP  |d DKDLA  |d CCO  |d E7B  |d CN5CF  |d UAB  |d CEF  |d AU@  |d OCLCO  |d OCLCA  |d OCLCQ  |d OCLCO  |d OCLCQ  |d OCL  |d OCLCO  |d SXB 
020 |a 9781601192134  |q (electronic bk.) 
020 |a 1601192134  |q (electronic bk.) 
020 |a 9781429479967 
020 |a 1429479965 
020 |z 092960086X 
020 |z 9780929600864 
035 |a (OCoLC)123432930  |z (OCoLC)164625553  |z (OCoLC)290554537  |z (OCoLC)300865713  |z (OCoLC)475464209  |z (OCoLC)475661879  |z (OCoLC)568141738  |z (OCoLC)608565676  |z (OCoLC)646752496  |z (OCoLC)755664788  |z (OCoLC)1075502191  |z (OCoLC)1424897617 
042 |a dlr 
245 0 0 |a Extrapolation of radiation-induced cancer risks from nonhuman experimental systems to humans. 
260 |a Bethesda, MD :  |b National Council on Radiation Protection and Measurements,  |c ©2005. 
300 |a 1 online resource (xii, 267 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a NCRP report ;  |v no. 150 
500 |a "Recommendations of the National Council on Radiation Protection and Measurements." 
500 |a "Issued November 2005." 
504 |a Includes bibliographical references (pages 194-241) and index. 
505 0 |a Cover -- Preface -- Contents -- 1. Executive Summary and Recommendations -- 1.1 Why Is Extrapolation Still Required? -- 1.2 Summary of Findings -- 1.2.1 Historical Aspects -- 1.2.2 Neoplastic Disease -- 1.2.3 Somatic Genetic Damage at Molecular and Cellular Levels -- 1.2.4 Extrapolation Models and Methods -- 1.3 Conclusions -- 1.4 Recommendations -- 2. Introduction -- 3. History of Extrapolation: Nonhuman Experimental Systems to Humans -- 3.1 Introduction -- 3.2 Lessons Learned from Genetic Risks -- 3.2.1 Methods of Estimation 
505 8 |a 3.2.2 Discussion of Methods of Estimating Genetic Risk3.2.3 Role of Genetics in the Estimation of Somatic Risks -- 3.3 Somatic Risks -- 4. Tissue and Organ Differences Among Species with Emphasis on the Cells of Origin of Cancers -- 4.1 Introduction -- 4.2 Hematopoietic System -- 4.2.1 Introduction: Leukemias and Lymphomas -- 4.2.2 Comparison of Radiation-Induced Leukemias Among Species -- 4.2.3 Pathology and Dose-Response Relationships -- 4.2.4 Comparison of Hematopoietic Systems -- 4.2.5 Target Cells 
505 8 |a ""4.2.6 Comparison of Cytogenetic Processes: Common or Species-Specific Patterns""""4.2.7 Leukemogenesis Resulting from Gene Rearrangements""; ""4.2.8 Secondary Cytogenetic Lesions Associated with Leukemia Promotion and Progression""; ""4.2.9 Hematopoietic Cell Origins of the Putative “Criticalâ€? Genic Lesions and the Nature of Induced Genic Dysfunctions""; ""4.2.10 Cooperating Oncogenes in Lymphoid Neoplasias""; ""4.2.11 Cooperating Oncogenes in Myeloid Neoplasias""; ""4.2.12 Hematopoeitic Microenvironment""; ""4.2.13 Summary""; ""4.3 Lung""; ""4.3.1 Introduction"" 
505 8 |a 4.3.2 Adenocarcinoma4.3.3 Squamous-Cell Carcinoma -- 4.3.4 Small-Cell Lung Carcinoma -- 4.3.5 Large-Cell Carcinoma -- 4.3.6 Summary -- 4.4 Breast -- 4.4.1 Histogenesis of Mammary Glands and Mammary Cancer -- 4.4.2 Hormones and Mammary Carcinogenesis -- 4.4.3 Cellular Origins of Mammary Cancer -- 4.4.4 Summary -- 4.5 Thyroid -- 4.5.1 General Background -- 4.5.2 Histogenesis of the Thyroid Gland and Thyroid Cancer -- 4.5.3 Thyroid Function and its Control -- 4.5.4 Cellular Economy of the Thyroid Gland and the Origin of Cancer -- 4.5.5 Summary -- 4.6 Skin 
505 8 |a 4.6.1 Introduction4.6.2 Epidermal Cancers -- 4.6.3 Melanoma -- 4.6.4 Tumors of the Dermis -- 4.6.5 Mechanisms of Epidermal Carcinogenesis -- 4.6.6 Importance of Interactions -- 4.6.7 Summary -- 4.7 Gastrointestinal Tract -- 4.7.1 Introduction -- 4.7.2 Stomach -- 4.7.3 Small Intestine -- 4.7.4 Colorectal Tumors -- 4.7.5 Summary -- 4.8 Bone -- 4.8.1 Humans -- 4.8.2 Mice -- 4.8.3 Rats -- 4.8.4 Dogs -- 4.8.5 Summary -- 5. Radiation Effects at the Molecular and Cellular Levels -- 5.1 Introduction 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
590 |a Knovel  |b Knovel (All titles) 
650 0 |a Radiation carcinogenesis. 
650 0 |a Radiation  |x Toxicology. 
650 0 |a Animal models in research. 
650 0 |a Carcinogenicity testing. 
650 0 |a Diseases  |x Animal models. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
710 2 |a National Council on Radiation Protection and Measurements. 
776 0 8 |i Print version:  |t Extrapolation of radiation-induced cancer risks from nonhuman experimental systems to humans.  |d Bethesda, MD : National Council on Radiation Protection and Measurements, ©2005  |z 092960086X  |w (DLC) 2005031014  |w (OCoLC)62152910 
830 0 |a NCRP report ;  |v no. 150. 
856 4 0 |u https://proxy.k.utb.cz/login?url=https://app.knovel.com/hotlink/toc/id:kpERICRNE3/extrapolation-of-radiation?kpromoter=marc  |y Full text 

Similar Items