Nanomedicine for cancer therapy : from chemotherapeutic to hyperthermia-based therapy

This Brief focuses on the cancer therapy available till date, from conventional drug delivery to nanomedicine in clinical trial. In addition, it reports on future generation based nanotherapeutics and cancer theranostic agent for effective therapeutic diagnosis and treatment. Breast cancer was chose...

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Bibliographic Details
Main Author: Kumar, Piyush.
Other Authors: Srivastava, Rohit.
Format: eBook
Language: English
Published: Cham, Switzerland : Springer, 2016.
Series: SpringerBriefs in applied sciences and technology. Nanotheranostics.
Subjects:
ISBN: 9783319458267
9783319458250
Physical Description: 1 online resource

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020 |a 9783319458267  |q (electronic bk.) 
020 |z 9783319458250 
035 |a (OCoLC)964530204 
100 1 |a Kumar, Piyush. 
245 1 0 |a Nanomedicine for cancer therapy :  |b from chemotherapeutic to hyperthermia-based therapy /  |c Piyush Kumar, Rohit Srivastava. 
260 |a Cham, Switzerland :  |b Springer,  |c 2016. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
490 1 |a SpringerBriefs in applied sciences and technology, Nanotheranostics 
505 0 |a Preface; Contents; 1 Nanomedicine for Cancer Therapy; Abstract; 1 Introduction; 2 Conventional Therapy for Breast Cancer; 2.1 Limitation of Conventional Therapy; 3 Multiple Drug Resistance (MDR); 3.1 Drug Efflux and Decrease in Drug Uptake; 3.2 Alteration in Drug Target (Topoisomerase II); 3.3 Change in Detoxifying Enzyme Such Glutathione S-Transferase and Cytochrome P450; 3.4 Increase in DNA Repair; 3.5 Inhibition of Apoptosis by Disruption of Cell Signalling; 3.6 Therapy with Multiple Drug Delivery; 3.6.1 A: Combination of Two Drug Molecule. 
505 8 |a 3.6.2 B: Combination a Biologics and a Drug Molecule3.6.3 C: Drug Delivery Through Carrier or Nanomedicine; 4 Application of Nanoparticles in Cancer; 4.1 Types of Carriers (NPs) and Its Role in Nanomedicine for Cancer Therapy; 4.1.1 Organic Nanoparticle; 4.1.2 Inorganic Nanoparticle; 4.1.3 Metallic Nanoparticle; 4.1.4 Hybrid Nanoparticle; 4.1.5 Upconversion Nanoparticle; 5 Targeting or Delivery of NPs to the Cancer Cells; 5.1 Passive Targeting; 5.2 Active Targeting or Ligand-Mediated Targeting; 6 Role of Nanomedicine in Modern Day Cancer Therapy; 6.1 Gene Therapy. 
505 8 |a 6.1.1 DNA/SiRNA Based Gene Therapy6.2 Photodynamic Therapy; 6.2.1 Mechanism of Photodynamic Therapy; 6.2.2 Nanoparticle-Based Photodynamic Therapy; 6.3 Drug Resistance and Heat; 6.4 Therapy Based Thermal Ablation and Hyperthermia; 6.4.1 Types of Hyperthermia; 6.4.2 Heating Systems for Hyperthermia; 6.4.3 Electromagnetic Fields and Heating System/Equipment for Hyperthermia (Table€6); 6.5 Nanoparticles Based Hyperthermia; 6.6 Nanoparticles Based Magnetic Hyperthermia; 6.7 Nano Radiofrequency Hyperthermia: NRFH; 6.8 Photothermal Therapy (PTT) with Nanoparticles Formulation. 
505 8 |a 6.8.1 Nanoparticles Mediated Photothermal Therapy6.8.2 Metallic Nanoparticles Mediated PTT; 6.8.3 Dye Encapsulated Nanoparticles Based Photothermal Therapy; 6.9 Nano High Intensity Focussed Ultrasound Hyperthermia (NHIFU); 7 Combinatorial Therapy with Hyperthermia; 7.1 Hyperthermia and Radiation; 7.2 Hyperthermia and Drugs; 7.3 Hyperthermia with Photosensitization; 8 Clinical Trials, Success, and Challenges; 9 Conclusion; 10 Challenges; 11 Prospective; References. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This Brief focuses on the cancer therapy available till date, from conventional drug delivery to nanomedicine in clinical trial. In addition, it reports on future generation based nanotherapeutics and cancer theranostic agent for effective therapeutic diagnosis and treatment. Breast cancer was chosen as the model system in this review. The authors give emphasis to multiple drug resistance (MDR) and its mechanism and how to overcome it using the nanoparticle approach. . 
590 |a SpringerLink  |b Springer Complete eBooks 
650 0 |a Cancer  |x Treatment. 
650 0 |a Nanomedicine. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Srivastava, Rohit. 
776 0 8 |i Print version:  |z 3319458256  |z 9783319458250  |w (OCoLC)954425853 
830 0 |a SpringerBriefs in applied sciences and technology.  |p Nanotheranostics. 
856 4 0 |u https://proxy.k.utb.cz/login?url=https://link.springer.com/10.1007/978-3-319-45826-7  |y Plný text 
992 |c NTK-SpringerENG 
999 |c 99588  |d 99588 
993 |x NEPOSILAT  |y EIZ