Therapeutic and diagnostic nanomaterials

• Main Author: Devasena, T. (Author)
• Format: Electronic eBook
• Language: English
• Published: Singapore : Springer, [2016]
• Series: SpringerBriefs in applied sciences and technology. Nanotheranostics.
• Subjects: Biomedical materials.; elektronické knihy; electronic books
• ISBN: 9789811009235; 9789811009211
• ISSN: 2191-530X
• Physical Description: 1 online resource (vii, 109 pages) : illustrations (some color)

This brief highlights nanoparticles used in the diagnosis and treatment of prominent diseases and toxic conditions. Ecofriendly methods which are ideal for the synthesis of medicinally valued nanoparticles are explained and the characteristic features of these particles projected. The role of these...

Table of Contents:

• Introduction; 1 Diagnostic and Therapeutic Nanomaterials; 1.1 Why Are Nanoparticles Ideal Diagnostic and Therapeutic Agents?; 1.2 Nanotheranostic Candidates; 1.3 Safety Concerns with Medically Important Nanoparticles; References; 2 Multifunctional Nanoparticles; 2.1 Stabilizing Ligands; 2.1.1 Biomolecules; 2.1.2 Avidin-Biotin Conjugate; 2.2 Targeting Ligands; 2.2.1 Antibodies; 2.2.2 Antibody Fragments/Antibody Derivatives; 2.2.3 Peptides; 2.2.4 Aptamers; 2.2.5 Small Targeting Molecules; 2.3 Imaging Ligands; 2.4 Biocompatibility Ligands; 2.5 Anti-immunogenic Ligands; References.
• 3 Biomarkers3.1 Biochemical Markers; 3.1.1 Cardiac Markers; 3.1.2 Cytokines; 3.1.3 Cancer Markers; 3.1.4 Cell Adhesion Molecules (CAMs); 3.1.5 Enzymes; 3.1.6 Hematological Biomarkers; 3.1.7 Oxidative Stress Markers; 3.2 Genetic Markers; 3.2.1 Single Locus Markers; 3.2.2 Multiple Loci Markers; 3.2.3 Examples of Genetic Markers; 3.3 Histopathological Markers; References; 4 Diagnostic and Therapeutic Techniques; 4.1 Diagnostic Techniques Using Nanoparticles; 4.2 Therapeutic Techniques Using Nanoparticles; References; 5 Nanotoxicity and Risk Assessment; 5.1 CNT Toxicity.
• 5.2 Silica and Titania Nanoparticles5.3 Fullerene; 5.4 Quantum Dots; 5.5 Manganese Nanoparticles; References; 6 Applications of Select Nanomaterials; 6.1 Dendrimers; 6.1.1 Dendrimers in Therapeutic Applications; 6.1.2 Nanoscale Containers; 6.1.3 Dendrimers in Gene Transfection; 6.1.4 Dendrimers in Diagnostic Applications; 6.2 Antibodies; 6.2.1 Blood-Brain Barrier; 6.2.2 Nanoimmunosensors; 6.2.3 Types of Immunosensors; 6.2.4 Preparation of HDL-like Nanoparticles; 6.2.5 Plaques in an ApoE-/- Model; 6.2.6 Gold Nanoparticles.
• 6.2.6.1 Applications of Gold Nanoparticles with Enhanced Raman Spectroscopy6.3 Lipid-Based Nanocarriers; 6.3.1 Liposomes; 6.3.1.1 Stealth Liposomes: The Second-Generation Liposomes; 6.3.1.2 Applications of Nanoliposomes; Liposomal Anticancer Agents; Liposomal Anti-infective Drugs; Vaccine Delivery; Diagnostic Applications of Liposomes; 6.3.1.3 Solid-Lipid Nanoparticles; Applications of SLNs; 6.3.1.4 Cubosomes; Cubosomes for Ocular Inflammation; 6.4 Viral Nanoparticles; 6.4.1 Pharmacokinetics; 6.4.2 Disadvantages: Nonspecific Interaction and Immunogenicity; 6.4.3 Applications.
• 6.4.3.1 VNPs as Imaging Probes and Drug Carriers for Vascular Endothelial Cells6.4.3.2 CPMVs as Carriers for Delivering Cargo into the Central Nervous System; 6.5 Nanomaterial-Based Biomedical Devices; 6.5.1 Micropumps; 6.5.1.1 Components of Micropumps; 6.5.1.2 Applications and Advantages of a Silicon-Based HPMP; 6.5.2 Microneedles; 6.5.2.1 Applications of Microneedles; 6.5.3 Implantable Microchip Devices for Drug Delivery; 6.5.4 Nanorobots; 6.5.4.1 Tools or Components of Nanorobots; 6.5.4.2 Nanorobot Locomotion; 6.5.4.3 Power for the Navigation of Nanorobots; 6.5.4.4 Tracking of Nanorobots.