Marburg- and ebolaviruses : from ecosystems to molecules

This volume provides an overview of recent advances in our understanding of the biology of marburg- and ebolaviruses. It focuses on four essential areas: 1) ecology, outbreaks and clinical management, 2) disease, pathogenesis and protection, 3) virus replication inside the cell, and 4) molecular too...

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Bibliographic Details
Main Authors: Mühlberger, Elke, (Author), Hensley, Lisa L., (Author), Towner, Jonathan S., (Author)
Format: eBook
Language: English
Published: Cham, Switzerland : Springer, 2017.
Series: Current topics in microbiology and immunology ; 411.
Subjects:
RNA viruses.
elektronické knihy
electronic books
ISBN: 9783319689487
9783319689463
Physical Description: 1 online resource

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245 0 0 |a Marburg- and ebolaviruses :  |b from ecosystems to molecules /  |c Elke Mühlberger, Lisa L. Hensley, Jonathan S. Towner, editors. 
264 1 |a Cham, Switzerland :  |b Springer,  |c 2017. 
300 |a 1 online resource 
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490 1 |a Current topics in microbiology and immunology,  |x 0070-217X ;  |v volume 411 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This volume provides an overview of recent advances in our understanding of the biology of marburg- and ebolaviruses. It focuses on four essential areas: 1) ecology, outbreaks and clinical management, 2) disease, pathogenesis and protection, 3) virus replication inside the cell, and 4) molecular tools for virus study and taxonomy. For 50 years, these viruses have spilled over sporadically and without warning from their wildlife reservoirs, often causing major outbreaks and high fatalities. The consequences can be devastating, with a clear potential for global reach, as demonstrated by the 2013 West African outbreak of Ebola virus, which led to over 28,000 reported cases across three continents and more than 11,000 deaths. Given the international threat posed by these viruses, the pace and scope of basic research have also greatly intensified, ranging from studies of virus emergence, epidemiology, antiviral countermeasures and human disease to detailed mechanistic studies of virus entry, replication, virion assembly and protein structure. Written by internationally respected experts, this book will appeal to a wide audience and be a valuable resource for basic researchers, clinicians and advanced students alike. 
505 0 |a Filovirus Research: How it began -- Ecology of Filoviruses -- West Africa 2013 Ebola: From Virus Outbreak to Humanitarian Crisis -- Clinical Management of Ebola Virus Disease Patients in Low Resource Settings -- Clinical Management of Patients with Ebola Virus Disease in High Resource Settings -- Ebola Virus Disease in Humans: Pathophysiology and Immunity -- Nonhuman Primate Models of Ebola Virus Disease -- Small Animal Models for Studying Filovirus Pathogenesis -- Accelerating Vaccine Development during the West African Ebola Virus Disease Outbreak -- Therapeutics against Filovirus Infection -- Filovirus Strategies to Escape Antiviral Responses -- Mechanisms of Filovirus Entry -- Inside the Cell: Assembly of Filoviruses -- Filovirus Structural Biology: The Molecules in the Machine -- Reverse Genetics of Filoviruses -- Guide to the Correct Use of Filoviral Nomenclature. 
504 |a Includes bibliographical references at the end of each chapters. 
590 |a SpringerLink  |b Springer Complete eBooks 
650 0 |a RNA viruses. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Mühlberger, Elke,  |e author. 
700 1 |a Hensley, Lisa L.,  |e author. 
700 1 |a Towner, Jonathan S.,  |e author. 
776 0 8 |i Print version:  |t Marburg- and ebolaviruses.  |d Cham, Switzerland : Springer, 2017  |z 3319689460  |z 9783319689463  |w (OCoLC)1004074352 
830 0 |a Current topics in microbiology and immunology ;  |v 411. 
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