Membrane organization and dynamics

This volume brings together information on membrane organization and dynamics from a variety of spectroscopic, microscopic and simulation approaches, spanning a broad range of time scales. The implication of such dynamic information on membrane function in health and disease is a topic of contempora...

Full description

Saved in:
Bibliographic Details
Other Authors: Chattopadhyay, Amitabha, 1956- (Editor)
Format: eBook
Language: English
Published: Cham, Switzerland : Springer, 2017.
Series: Springer series in biophysics ; v. 20.
Subjects:
Membranes (Biology) > Mechanical properties.
elektronické knihy
electronic books
ISBN: 9783319666013
9783319666006
Physical Description: 1 online resource

Cover

Table of contents

LEADER 06526cam a2200469Ii 4500
001 97677
003 CZ-ZlUTB
005 20240914110740.0
006 m o d
007 cr cnu---unuuu
008 171212s2017 sz ob 000 0 eng d
040 |a N$T  |b eng  |e rda  |e pn  |c N$T  |d GW5XE  |d N$T  |d OCLCF  |d UAB  |d VT2  |d AZU  |d UPM  |d IOG  |d MERER  |d COO  |d OCLCQ  |d SNK  |d OCLCQ  |d AUD  |d U3W  |d YDX  |d COS  |d COF  |d W2U  |d UWW  |d EBLCP  |d KSU  |d ESU  |d WYU  |d LVT  |d UKMGB  |d CAUOI  |d UKAHL  |d OCLCQ  |d ERF  |d OCLCQ  |d SRU  |d AJS 
020 |a 9783319666013  |q (electronic bk.) 
020 |z 9783319666006  |q (print) 
024 7 |a 10.1007/978-3-319-66601-3  |2 doi 
035 |a (OCoLC)1015239867  |z (OCoLC)1021189747  |z (OCoLC)1027002589  |z (OCoLC)1032271818  |z (OCoLC)1048143615 
245 0 0 |a Membrane organization and dynamics /  |c Amitabha Chattopadhyay, editor. 
264 1 |a Cham, Switzerland :  |b Springer,  |c 2017. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
490 1 |a Springer series in biophysics ;  |v 20 
504 |a Includes bibliographical references. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |6 880-01  |a This volume brings together information on membrane organization and dynamics from a variety of spectroscopic, microscopic and simulation approaches, spanning a broad range of time scales. The implication of such dynamic information on membrane function in health and disease is a topic of contemporary interest. The chapters cover various aspects of membrane lipid and protein dynamics, explored using a battery of experimental and theoretical approaches. The synthesis of information and knowledge gained by utilizing multiple approaches will provide the reader with a comprehensive understanding of the underlying membrane dynamics and function, which will help to develop robust dynamic models for the understanding of membrane function in healthy and diseased states. In the last few years, crystal structures of an impressive number of membrane proteins have been reported, thanks to tremendous advances in membrane protein crystallization techniques. Some of these recently solved structures belong to the G protein-coupled receptor (GPCR) family, which are particularly difficult to crystallize due to their intrinsic flexibility. Nonetheless, these static structures do not provide the necessary information to understand the function of membrane proteins in the complex membrane milieu. This volume will address the dynamic nature of membrane proteins within the membrane and will provide the reader with an up-to date overview of the theory and practical approaches that can be used. This volume will be invaluable to researchers working in a wide range of scientific areas, from biochemistry and molecular biology to biophysics and protein science. Students of these fields will also find this volume very useful. This book will also be of great use to those who are interested in the dynamic nature of biological processes. 
505 0 |a Intro; Preface; Contents; About the Editor; Chapter 1: What Is So Unique About Biomembrane Organization and Dynamics?; 1.1 Cellular Membranes as Identity Markers; 1.2 What Holds the Membrane Together?; 1.3 Unique Features of Biomembrane Organization and Dynamics; 1.4 Spatiotemporal Scales of Membrane Phenomena; 1.5 Future Perspectives: What Lies Ahead; References; Chapter 2: Dynamics and Organization of Archaeal Tetraether Lipid Membranes; 2.1 Chemical Structures of Bipolar Tetraether Lipids; 2.1.1 Bipolar Tetraether Lipids Isolated from Archaea 
505 8 |a 2.1.2 Synthetic Bipolar Tetraether Lipid Analogues2.2 BTL Membranes; 2.3 Stability of BTL Membranes; 2.4 Phase Behaviors of BTL Membranes; 2.5 Membrane Lateral Diffusion; 2.6 Probe Rotations and Insertion in BTL Membranes; 2.7 Gradient of Membrane Dynamics Along the Membrane Normal; 2.8 Solute Permeation in BTL Membranes; 2.9 Role of Sugar Moieties in BTL Membrane Physical Properties; 2.10 Lateral Organization in BTL Membranes; 2.11 Concluding Remarks; References; Chapter 3: Effects of Oxidative Stress, Hyperglycemia, and Hypercholesterolemia on Membrane Structural Organization and the In ... 
505 8 |a 3.1 Cholesterol Is an Important Component of Cellular Membranes3.2 Effects of Oxidation, Hyperglycemia, and Hypercholesterolemia on Cellular Membranes; 3.3 Effects of Omega-3 Long Chain Polyunsaturated Acids on Membranes; 3.4 Differential Effects of Fatty Acids: EPA and DHA; 3.5 Summary; References; Chapter 4: Interaction of Amphiphilic Molecules with Lipid Bilayers: Kinetics of Insertion, Desorption and Translocation; 4.1 Experimental Approaches to Characterize the Interaction Between Small Molecules and Lipid Bilayers 
505 8 |a 4.1.1 Solutes with High Solubility in the Aqueous Media and Insoluble in the Lipid Bilayer4.1.2 Solutes with a Moderate Solubility in the Aqueous Media and in the Lipid Bilayer; 4.1.3 Solutes with Very Low Solubility in the Aqueous Media and a High Partition into the Lipid Bilayer; 4.2 Molecular Dynamics Simulations to Characterize the Interaction and Permeation of Small Molecules Through Lipid Bilayers; 4.2.1 General Description on the Generation of the PMF Profile Through Lipid Bilayers; 4.2.2 The General Simulation Protocol; 4.2.3 Sampling Issues 
505 8 |a 4.2.4 The General Description of the PMF Profile4.2.5 How to Obtain Kinetics from the PMF; 4.2.6 Calculation of Permeability Coefficients from MD Simulations; 4.3 Concluding Remarks; References; Chapter 5: Multidimensional Microscopy: Application to Membrane Protein Structure; 5.1 Introduction; 5.2 Formalism; 5.3 An Archetypical Membrane Protein: The Epidermal Growth Factor Receptor; 5.4 Multidimensional Microscopy of EGFR on Intact Cells; 5.4.1 In-Cell Quaternary Structure of EGFR in the Absence of EGF (ICS, Polarization, FCS) 
590 |a SpringerLink  |b Springer Complete eBooks 
650 0 |a Membranes (Biology)  |x Mechanical properties. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Chattopadhyay, Amitabha,  |d 1956-  |e editor. 
776 0 8 |i Printed edition:  |z 9783319666006 
830 0 |a Springer series in biophysics ;  |v v. 20. 
856 4 0 |u https://proxy.k.utb.cz/login?url=https://link.springer.com/10.1007/978-3-319-66601-3  |y Plný text 
992 |c NTK-SpringerBLS 
999 |c 97677  |d 97677 
993 |x NEPOSILAT  |y EIZ 

Similar Items