Precision medicine, CRISPR, and genome engineering : moving from association to biology and therapeutics

"This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine. Chapters feature contributions from leaders in stem cell therapy and bi...

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Bibliographic Details
Other Authors Tsang, Stephen H. (Editor), Church, George M. (writer of foreword.)
Format Electronic eBook
LanguageEnglish
Published Cham, Switzerland : Springer, [2017]
SeriesAdvances in experimental medicine and biology ; v. 1016.
Subjects
Genetic engineering.
elektronické knihy
electronic books
Online AccessFull text
ISBN9783319639048
9783319639031
ISSN2214-8019 ;
Physical Description1 online resource (ix, 178 pages) : color illustrations

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Table of Contents:
  • Part 1. Introduction to the CRISPR revolution. Viral vectors, engineered cells and the CRISPR revolution / James E. DiCarlo, Anurag Deeconda, and Stephen H. Tsang
  • Combined engineered nucleases with adeno-associated viral vectors for therapeutic gene editing / Benjamin E. Epstein and David V. Schaffer
  • part 2. CRISPR in model systems. From reductionism to holism: toward a more complete view of development through genome engineering / Rebecca K. Delker and Richard S. Mann
  • A transgenic core facility's experience in genome editing revolution / Celvie L. Yuan and Yueh-Chiang Hu
  • Genome editing to study Ca² homeostasis in zebrafish cone photoreceptors / Susan E. Brockerhoff
  • CRISPR: from prokaryotic immune systems to plant genome editing tools / Anindya Bandyopadhyay, Shamik Mazumdar, Xiaojia Yin, and William Paul Quick
  • part 3. The future of CRISPR. Target discovery for precision medicine using high-throughput genome engineering / Xinyi Guo, Poonam Chitale, and Neville E. Sanjana
  • CRISPR in the retina: evaluation of future potential / Galaxy Y. Cho, Sally Justus, Jesse D. Sengillo, and Stephen H. Tsang
  • The future of CRISPR applications in the lab, the clinic and society / Soren H. Hough and Ayokunmi Ajetunmobi.

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