http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Precision medicine, CRISPR, and genome engineering
moving from association to biology and therapeutics
1 online resource (ix, 178 pages) : color illustrations
"This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine. Chapters feature contributions from leaders in stem cell therapy and biology, providing a comprehensive view of the application of gene therapy in numerous fields with an emphasis on ophthalmology, stem cells, and agriculture. The book also highlights recent major technological advances, including ZFN, TALEN, and CRISPR. Precision Medicine, CRISPR, and Genome Engineering is part of the highly successful Advances in Experimental Medicine and Biology series. It is an indispensable resource for researchers and students in genetics as well as clinicians"--Publisher's description.
Part 1. Introduction to the CRISPR revolution. Viral vectors, engineered cells and the CRISPR revolution / James E. DiCarlo, Anurag Deeconda, and Stephen H. Tsang -- Combined engineered nucleases with adeno-associated viral vectors for therapeutic gene editing / Benjamin E. Epstein and David V. Schaffer -- part 2. CRISPR in model systems. From reductionism to holism: toward a more complete view of development through genome engineering / Rebecca K. Delker and Richard S. Mann -- A transgenic core facility's experience in genome editing revolution / Celvie L. Yuan and Yueh-Chiang Hu -- Genome editing to study Ca² homeostasis in zebrafish cone photoreceptors / Susan E. Brockerhoff -- CRISPR: from prokaryotic immune systems to plant genome editing tools / Anindya Bandyopadhyay, Shamik Mazumdar, Xiaojia Yin, and William Paul Quick -- part 3. The future of CRISPR. Target discovery for precision medicine using high-throughput genome engineering / Xinyi Guo, Poonam Chitale, and Neville E. Sanjana -- CRISPR in the retina: evaluation of future potential / Galaxy Y. Cho, Sally Justus, Jesse D. Sengillo, and Stephen H. Tsang -- The future of CRISPR applications in the lab, the clinic and society / Soren H. Hough and Ayokunmi Ajetunmobi.
Stephen H. Tsang, editor ; foreword by George M. Church.
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Advances in experimental medicine and biology ; v. 1016