Current progress in medical mycology

Infections caused by fungi have recently attracted the attention of both clinicians and basic researchers given the heavy burden they represent for any health system. The mortality and morbidity rates associated to mycosis are progressively rising simply because some of these diseases are still negl...

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Bibliographic Details
Other Authors: Mora-Montes, Hector Manuel, (Editor), Lopes-Bezerra, Leila M., (Editor)
Format: eBook
Language: English
Published: Cham, Switzerland : Springer, [2017]
Subjects:
Medical mycology.
Mycology.
elektronické knihy
electronic books
ISBN: 9783319641133
9783319641126
Physical Description: 1 online resource : illustrations

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245 0 0 |a Current progress in medical mycology /  |c Héctor M. Mora-Montes, Leila M. Lopes-Bezerra, editors. 
264 1 |a Cham, Switzerland :  |b Springer,  |c [2017] 
264 4 |c ©2017 
300 |a 1 online resource :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a Infections caused by fungi have recently attracted the attention of both clinicians and basic researchers given the heavy burden they represent for any health system. The mortality and morbidity rates associated to mycosis are progressively rising simply because some of these diseases are still neglected by health-care workers and due to the changing sensitivity to antifungal drugs displayed by these organisms. In this book, both researchers and clinicians working in the medical mycology field explore the most recent literature about specific mycosis; placing in one concise chapter thoroughly revisions of the current knowledge on virulence factors, recognition by immune cells, immunoevasion, epidemiology, new diagnosis trends and therapeutics. This book is recommended to researchers, physicians and students interested in medical mycology. 
505 0 |a Preface -- Contents -- Contributors -- Chapter 1: Introduction to Medical Mycology -- 1.1 Definition and Structure -- 1.2 Emergence of Challenge Due to Fungal Infections -- 1.3 Spectrum of Fungal Infections -- 1.3.1 Superficial Mycoses -- 1.3.2 Invasive/Opportunistic Mycoses -- 1.3.3 Endemic Mycoses -- 1.3.4 Allergic Manifestations -- 1.4 Classification -- 1.5 Epidemiology of Fungal Infections -- 1.5.1 Global Burden of Disease -- 1.5.2 Predisposing Factors for Fungal Infections -- 1.5.3 Geographical Distribution 
505 8 |a 1.5.4 Community Acquired Fungal Infections1.5.5 Nosocomial Fungal Infections -- 1.6 Fungal Infection Immunity and Pathogenesis -- 1.6.1 Innate Immunity -- 1.6.2 Adaptive Immunity -- 1.6.3 Fungal Virulence -- 1.6.4 Tissue Reaction -- 1.7 Diagnosis of Fungal Infections -- 1.7.1 Radiological Imaging -- 1.7.2 Conventional and Culture Based Diagnosis -- 1.7.3 Sepsis Biomarkers -- 1.7.4 Serology -- 1.7.5 Molecular Detection -- 1.8 Treatment -- 1.9 Fungal Vaccines -- References -- Chapter 2: Antifungal Drugs 
505 8 |a 2.1 Polyenes (Amphotericin B Deoxycholate and Its Lipid-ÂƯAssociated Formulations)2.1.1 Amphotericin B Deoxicholate -- 2.1.1.1 Chemical Structure -- 2.1.1.2 Mechanism of Action -- 2.1.1.3 Pharmacokinetics and Pharmacodynamics -- 2.1.1.4 Spectrum of Activities and Resistance -- 2.1.1.5 Clinical Uses -- 2.1.1.6 Dosing -- 2.1.1.7 Adverse Events and Toxicity -- 2.1.1.8 Contraindication -- 2.1.1.9 Drug Interactions -- 2.1.1.10 Use in Special Population -- 2.1.2 Lipid Formulations of Amphotericin B -- 2.1.2.1 Dosing -- 2.1.2.2 Adverse Events and Toxicity 
505 8 |a 2.2 Triazole Antifungal Agents2.2.1 General Properties -- 2.2.1.1 Chemical Structure -- 2.2.1.2 Mechanism of Action -- 2.2.1.3 Pharmacokinetics -- 2.2.1.4 Spectrum of Activity and Resistance -- 2.2.1.5 Clinical Utility -- 2.2.1.6 Adverse Events and Drug Interactions -- 2.2.1.7 Dosing and Administration. Use in Special Populations -- 2.2.2 Individual Agents -- 2.2.2.1 Itraconazole -- 2.2.2.2 Fluconazole -- 2.2.2.3 Voriconazole -- 2.2.2.4 Posaconazole -- 2.2.2.5 Isavuconazole 
505 8 |a 2.2.3 Newer and Investigational Agents: Efinaconazole, Albaconazole, Ravuconazole and Others2.3 Echinocandins -- 2.3.1 Chemical Structure -- 2.3.2 Mechanism of Action -- 2.3.3 Pharmacokinetics and Pharmacodynamics -- 2.3.4 Spectrum of Activity and Resistance -- 2.3.5 Clinical Uses -- 2.3.6 Adverse Events and Toxicity -- 2.3.7 Drug Interactions -- 2.3.8 Use in Special Population and Dose Adjustments -- 2.3.9 Adult Dosing -- 2.3.10 New Echinocandin -- 2.4 Flucytosine -- 2.4.1 Chemical Structure -- 2.4.2 Mechanism of Action 
590 |a SpringerLink  |b Springer Complete eBooks 
650 0 |a Medical mycology. 
650 0 |a Mycology. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Mora-Montes, Hector Manuel,  |e editor. 
700 1 |a Lopes-Bezerra, Leila M.,  |e editor. 
776 0 8 |i Print version:  |t Current progress in medical mycology.  |d Cham, Switzerland : Springer, [2017]  |z 9783319641126  |z 3319641123  |w (OCoLC)992747571 
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