Mechanosensory transduction in Drosophila melanogaster

This book offers an essential introduction for all graduate students and researchers who are working on or interested in mechanotransduction using fruit flies as their model organisms. Designed for accessibility, it follows a simple five-chapter structure, beginning with a general introduction to me...

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Bibliographic Details
Main Author Liang, Xin, 1981-
Other Authors Sun, Landi, Liu, Zhen
Format Electronic eBook
LanguageEnglish
Published Singapore : Springer, 2017.
SeriesSpringerBriefs in biochemistry and molecular biology.
Subjects
Mechanoreceptors.
Drosophila melanogaster.
elektronické knihy
electronic books
Online AccessFull text
ISBN9789811065262
9789811065255
Physical Description1 online resource : illustrations (some color)

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Table of Contents:
  • Preface
  • Acknowledgments
  • Contents
  • Chapter 1: Overview of Mechanosensory Transduction
  • 1.1 Mechanosensory Transduction
  • 1.1.1 Sensory Transduction
  • 1.1.2 Mechanosensory Transduction in Physiology
  • 1.1.3 Dysfunction of Mechanotransduction in Diseases
  • 1.1.4 Summary
  • 1.2 Model I: Bacteria
  • 1.2.1 Mechanotransduction in Bacteria
  • 1.2.2 Mechanosensitive Channels (Msc) (Kung et al. 2010)
  • 1.2.3 The Surface Attaching Apparatus (Persat et al. 2015; Persat 2017)
  • 1.3 Model II: Touch-Sensitive Neurons in C. elegans
  • 1.3.1 Mechanosensation in C. elegans1.3.2 A Good Animal Model
  • 1.3.3 Mechanosensory Neurons in C. elegans
  • 1.3.4 The Transduction Apparatus in C. elegans Touch Receptors (Goodman 2006; Lumpkin et al. 2010)
  • 1.4 Model III: Inner Ear Hair Cells
  • 1.4.1 Function and Structure of the Hair Cells (Gillespie and Muller 2009)
  • 1.4.2 Mechanotransduction Apparatus in Hair Cells
  • 1.5 Summary
  • References
  • Chapter 2: â#x80;#x9C;Gating-Springâ#x80;#x9D; Model for Mechanotransduction
  • 2.1 A Minimal Mechanotransduction Apparatus
  • 2.1.1 The Processer
  • 2.1.2 The Responder2.1.3 Examples
  • 2.2 The â#x80;#x9C;Gating-Springâ#x80;#x9D; Model
  • 2.2.1 Overview
  • 2.2.2 The Simple Mechanical Description
  • 2.2.3 Model Predictions: Sensitivity and Dynamic Range
  • 2.2.4 Functional Implications
  • 2.2.5 Molecular Basis
  • References
  • Chapter 3: Mechanoreceptors in Drosophila melanogaster
  • 3.1 Overview of Fly Mechanoreceptors
  • 3.2 Type IÂ Mechanoreceptors
  • 3.2.1 Bristle Sensilla
  • 3.2.2 Campaniform Sensilla
  • 3.2.3 Chordotonal Organ
  • 3.2.4 Ciliated Mechanoreceptors in Fly Larvae
  • 3.3 Type II Mechanoreceptors
  • 3.3.1 Class IÂ da Neuron3.3.2 Class II da Neuron
  • 3.3.3 Class III da Neuron
  • 3.3.4 Class IV da Neuron
  • 3.4 Summary
  • References
  • Chapter 4: Mechanotransduction in Drosophila Mechanoreceptors
  • 4.1 Overview of Fly Mechanotransduction
  • 4.2 Bristle Receptor
  • 4.2.1 Bristle Deflection
  • 4.2.2 Dendritic Tip and the Supporting Structures
  • 4.3 Campaniform Receptor
  • 4.3.1 Cuticle Deformation
  • 4.3.2 Dendritic Tip and the Supporting Structures
  • 4.3.3 Molecular Basis of Mechanotransduction
  • 4.4 Chordotonal Organ
  • 4.4.1 Fly Antenna and Johnstonâ#x80;#x99;s Organ4.4.2 Molecular Basis of Mechanotransduction
  • 4.5 Dendritic Arborization Neurons
  • 4.5.1 Overall Mechanics of da Neurons
  • 4.5.2 Molecular Basis of Mechanotransduction
  • References
  • Chapter 5: Drosophila Mechanotransduction Channels
  • 5.1 Overview
  • 5.2 No Mechanoreceptor Potential C (NompC)
  • 5.2.1 Overview on Fly NompC
  • 5.2.2 Structure of NompC
  • 5.2.3 Gating of NompC
  • 5.2.4 The Gating Spring of NompC
  • 5.2.5 NompC-Microtubule Interaction
  • 5.2.6 Physiological Roles of Fly NompC

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