Particulate technology for delivery of therapeutics

The book focuses on novel particulate technologies for the purpose of drug delivery to humans. Nowadays, macro and nano-scale particles are being investigated for targeted delivery of small and large biological macromolecules. The targeting of drugs can minimize the dosage regimen and reduces dose r...

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Bibliographic Details
Other Authors: Jana, Sougata., Jana, Subrata.
Format: eBook
Language: English
Published: Singapore : Springer, 2017.
Subjects:
Nanoparticles.
elektronické knihy
electronic books
ISBN: 9789811036477
9789811036460
Physical Description: 1 online resource

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Table of contents

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245 0 0 |a Particulate technology for delivery of therapeutics /  |c Sougata Jana, Subrata Jana, editors. 
260 |a Singapore :  |b Springer,  |c 2017. 
300 |a 1 online resource 
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505 0 |a Preface -- Contents -- About the Editors -- List of Contributors -- 1 Introduction to Novel Therapeutic Carriers -- Abstract -- 1 Introduction -- 2 Type of New Drug Carriers Systems -- 2.1 Transdermal Drug Delivery System -- 2.2 Carrier-Based Delivery Systems -- 2.3 Variable Release Delivery Systems -- 2.3.1 Osmotic Pump-Based Drug Delivery Systems -- 2.3.2 Reservoir-Based System -- 2.3.3 Matrix-Based Drug Delivery System -- 3 Preparation of Particulate Drug Delivery Systems -- 3.1 Dispersion Method -- 3.2 Solvent Evaporation Method 
505 8 |a 3.3 Emulsification or Solvent Diffusion Method3.4 Coacervation Method -- 3.5 Polymerization Method -- 3.6 Spray Drying and Congealing -- 3.7 Emulsification-Cross-Linking Method -- 3.8 Reverse Micellar Method -- 3.9 Supercritical Method -- 4 Release Kinetics from Nondegradable Polymeric Matrices -- 5 Release Kinetics from Biodegradable Polymeric Matrices -- 6 Concluding Remarks -- References -- 2 The Development and Achievement of Polymeric Nanoparticles for Cancer Drug Treatment -- Abstract -- 1 Introduction -- 1.1 Physiological Conditions of Tumor Tissues 
505 8 |a 1.2 Rationale of Cancer Nanotechnology1.3 Important Considerations in Nanoparticle-Based Delivery for Cancer Treatment -- 1.3.1 Passive Targeting of Nanoparticles: Enhanced Permeability and Retention (EPR) Effect -- 1.3.2 Active Targeting of Nanoparticles -- 2 Polymeric Nanocarriers for Therapeutic Applications in Cancer -- 2.1 Polymeric Micelles for Therapeutic Applications in Cancer -- 2.1.1 Doxorubicin (DOX) Conjugated Polymeric Micelles -- 2.1.2 Paclitaxel (PTX) Conjugated Polymeric Micelles -- 2.1.3 Other Chemotherapeutic Drugs Conjugated Polymeric Micelles 
505 8 |a 2.2 Polymeric Nanoparticles for Therapeutic Applications in Cancer2.2.1 PTX-Loaded Polymericnano Particles -- 2.2.2 DOX-Loaded Polymeric Nanoparticles -- 2.2.3 Other Chemotherapeutic Drugs Loaded Polymericnano Particles -- 3 Stimuli-responsive Polymeric Nanocarriers -- 3.1 Endogenous Stimuli-responsive Polymeric Nanoparticles and Micelles -- 3.2 Exogenous Stimuli-Responsive Polymeric Nanoparticles and Micelles -- 3.3 Multiple Stimuli-Responsive Polymeric Nanoparticles and Micelles -- 4 Conclusions -- Acknowledgements -- References 
505 8 |a 3 Nanotechnology-Based Immunotherapeutic Strategies for the Treatment of CancerAbstract -- 1 Introduction -- 2 Immunotherapies -- 3 Cancer and Immune System -- 3.1 Limitations of Existing Cancer Therapies -- 4 Basics and Strategies of Cancer Immunotherapy -- 4.1 Monoclonal Antibodies (mAbs) -- 4.2 Cancer Vaccines -- 4.3 Peptide Vaccines -- 4.4 Tumor Cell Based Vaccines -- 4.5 DNA Vaccines -- 4.6 Vector-Based Vaccines -- 4.7 Dendritic Cell Based Immunotherapy -- 4.8 Immune Checkpoint Inhibitors -- 4.9 Nonspecific Immunotherapies -- 4.9.1 Nano-immunotherapy 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a The book focuses on novel particulate technologies for the purpose of drug delivery to humans. Nowadays, macro and nano-scale particles are being investigated for targeted delivery of small and large biological macromolecules. The targeting of drugs can minimize the dosage regimen and reduces dose related potential toxicity of drug molecules, which in turn lead to increased potential compliance. Various types of organic, inorganic and polymer particles are currently being investigated. These are attracting the attention of the research workers in the field of drug delivery science and technology. This book covers polymersomes, inorganic- organic composites, gold nanoparticles biopolymer and synthetic polymer particles etc. All aspects of drug delivery in relation to each technology have been described including these advances, Easy to read and understand the content of each chapter Rich in up-to-date information regarding their application. 
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655 9 |a electronic books  |2 eczenas 
700 1 |a Jana, Sougata. 
700 1 |a Jana, Subrata. 
776 0 8 |i Print version:  |t Particulate technology for delivery of therapeutics.  |d Singapore : Springer, 2017  |z 9811036462  |z 9789811036460  |w (OCoLC)966572891 
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