Genome editing in neurosciences

This book is open access under a CC BY 4.0 license. Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technolog...

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Bibliographic Details
Other Authors: Jaenisch, Rudolf, (Editor), Zhang, Feng, 1982- (Editor), Gage, F. 1950- (Editor)
Format: eBook
Language: English
Published: Cham, Switzerland : Springer, 2017.
Series: Research and perspectives in neurosciences,
Subjects:
ISBN: 9783319601922
9783319601915
9783319649757
9783319649764
Physical Description: 1 online resource (xi, 123 pages) : color illustrations

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245 0 0 |a Genome editing in neurosciences /  |c Rudolf Jaenisch, Feng Zhang, Fred Gage, editors. 
264 1 |a Cham, Switzerland :  |b Springer,  |c 2017. 
300 |a 1 online resource (xi, 123 pages) :  |b color illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
490 1 |a Research and perspectives in neurosciences,  |x 0945-6082 
505 0 |a Introduction -- In vitro modeling of complex neurological diseases -- Aquatic model organisms in neurosciences : the genome editing revolution -- Genome-wide genetic screening in the mammalian CNS -- CRISPR/Cas9-mediated Knockin and Knockout in Zebrafish -- Dissecting the role of synaptic proteins with CRISPR -- Recurrently Breaking Genes in Neural Progenitors: Potential Roles of DNA Breaks in Neuronal Function, Degeneration and Cancer -- Neuroscience research using non-human primate models and genome editing -- Multiscale genome engineering: Genome-wide screens and targeted approaches -- Using Genome Engineering to Understand Huntington's Disease -- Therapeutic gene editing in muscles and muscle stem cells. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This book is open access under a CC BY 4.0 license. Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders. 
590 |a SpringerLink  |b Springer Complete eBooks 
650 0 |a Neurogenetics. 
650 0 |a Genetic engineering. 
650 0 |a RNA editing. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Jaenisch, Rudolf,  |e editor. 
700 1 |a Zhang, Feng,  |d 1982-  |e editor. 
700 1 |a Gage, F.  |q (Fred),  |d 1950-  |e editor. 
776 0 8 |i Print version:  |t Genome editing in neurosciences.  |d Cham, Switzerland : Springer, 2017  |z 9783319601915  |z 3319601911  |w (OCoLC)987282339 
830 0 |a Research and perspectives in neurosciences,  |x 0945-6082 
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