Store-operated Ca² entry (SOCE) pathways : emerging signaling concepts in human (patho)physiology

"This second edition of the book on Store-operated Ca2+ Entry Pathways has been updated with the newest discoveries that emerged in the field within the last five years. The crystal structure of the Ca2+ signaling core complex is described which adds to a new understanding of the molecular inte...

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Bibliographic Details
Other Authors Groschner, Klaus (Editor), Graier, Wolfgang F. (Editor), Romanin, Christoph (Editor)
Format Electronic eBook
LanguageEnglish
Published Cham, Switzerland : Springer, [2017]
EditionSecond edition.
SeriesAdvances in experimental medicine and biology ; v. 993.
Subjects
Calcium channels.
Cellular signal transduction.
Intracellular calcium.
elektronické knihy
electronic books
Online AccessFull text
ISBN9783319577326
9783319577319
ISSN2214-8019 ;
Physical Description1 online resource (xxix, 645 pages) : illustrations (chiefly color)

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Table of Contents:
  • SOCE: fundamental mechanistic concepts. Introduction / James W. Putney
  • The STIM-Orai pathway: STIM-Orai structures: isolated and in complex / Jinhui Zhu, Qingping Feng, Peter B. Stathopulos
  • The STIM-Orai pathway: Orai, the pore-forming subunit of the CRAC channel / Aparna Gudlur, Patrick G. Hogan
  • The STIM-Orai pathway: the interactions between STIM and Orai / Marc Fahrner, Rainer Schindl, Martin Muik, Isabella Derler, Christoph Romanin
  • The STIM-Orai pathway: conformational coupling between STIM and Orai in the activation of store-operated Ca2+ entry / Robert M. Nwokonko, Xiangyu Cai, Natalia A. Loktionova, Youjun Wang, Yandong Zhou [and others]
  • The STIM-Orai pathway: regulation of STIM and Orai by thiol modifications / Barbara A. Niemeyer
  • The STIM-Orai pathway: light-operated Ca2+ entry through engineered CRAC channels / Guolin Ma, Shufan Wen, Yun Huang, Yubin Zhou
  • STIM-TRPpathways and microdomain organization: Ca2+ influx channels: the Orai-STIM1-TRPC complexes / Dora Bodnar, Woo Young Chung, Dongki Yang, Jeong Hee Hong, Archana Jha, Shmuel Muallem
  • STIM-TRP pathways and microdomain organization: contribution of TRPC1 in store-operated Ca2+ entry: impact on Ca2+ signaling and cell function / Hwei Ling Ong, Indu S. Ambudkar
  • STIM-TRP pathways and microdomain organization: auxiliary proteins of the STIM/Orai complex / Jonathan Pacheco, Luis Vaca
  • SOCE: crosstalk between organelle and cellular compartments. introduction / Alexei V. Tepikin
  • New aspects of the contribution of ER to SOCE regulation: the role of the ER and ER-plasma membrane junctions in the regulation of SOCE / Hayley Dingsdale, Emmanuel Okeke, Lee Haynes, Gyorgy Lur, Alexei V. Tepikin
  • New aspects of the contribution of ER to SOCE regulation: TRPC proteins as a link between plasma membrane ion transport and intracellular Ca2+ stores / Alexis Bavencoffe, Michael Xi Zhu, Jin-bin Tian
  • The role of mitochondria in the activation/maintenance of SOCE: store-operated Ca2+ entry and mitochondria / András Spät, Gerg Szanda
  • The role of mitochondria in the activation/maintenance of SOCE: membrane contact sites as signaling hubs sustaining store-operated Ca2+ entry / Nicolas Demaurex, Daniele Guido
  • The role of mitochondria in the activation/maintenance of SOCE: the contribution of mitochondrial Ca2+ uptake, mitochondrial motility, and location to store-operated Ca2+ entry / Roland Malli, Wolfgang F. Graier
  • Tissue specificity: the role of organellar membrane nanojunctions in smooth muscle Ca2+ signaling / Nicola Fameli, A. Mark Evans, Cornelis van Breemen
  • Tissue specificity: SOCE: implications for Ca2+ handling in endothelial cells / Lothar A. Blatter
  • Tissue specificity: store-operated Ca2+ entry in cardiac myocytes / Martin D. Bootman, Katja Rietdorf
  • SOCE: molecular and cellular (patho)physiology. Introduction: overview of the pathophysiological implications of store-operated calcium entry in mammalian cells / Juan A. Rosado
  • Immunological disorders: regulation of Ca2+ signaling in T lymphocytes / Sonal Srikanth, Jin Seok Woo, Zuoming Sun, Yousang Gwack
  • Cardiovascular and hemostatic disorders: role of STIM and Orai proteins in vascular disorders / Jyoti Tanwar, Mohamed Trebak, Rajender K. Motiani
  • Cardiovascular and hemostatic disorders: SOCE and Ca2+ handling in platelet dysfunction / Jose J. Lopez, Gines M. Salido, Juan A. Rosado
  • Cardiovascular and hemostatic disorders: SOCE in cardiovascular cells: emerging targets for therapeutic intervention / Klaus Groschner, Niroj Shrestha, Nicola Fameli
  • Cardiac remodeling and disease: SOCE and TRPC signaling in cardiac pathology / Petra Eder
  • Cardiac remodeling and disease: current understanding of STIM1/Orai1-mediated store-operated Ca2+ entry in cardiac function and pathology / Fiona Bartoli, Jessica Sabourin
  • Neurological and motor disorders: neuronal store-operated Ca2+ signaling: an overview and its function / Sunitha Bollimuntha, Biswaranjan Pani, Brij B. Singh
  • Neurological and motor disorders: TRPC in the skeletal muscle / Sophie Saüc, Maud Frieden
  • Fertility: store-operated Ca2+ entry in germ cells: role in egg activation / Zoltan Machaty, Chunmin Wang, Kiho Lee, Lu Zhang
  • Metabolic disorders and cancer: hepatocyte store-operated Ca2+ channels in nonalcoholic fatty liver disease / Eunüs S. Ali, Grigori Y. Rychkov, Greg J. Barritt
  • Metabolic disorders and cancer: store-operated Ca2+ entry in cancer: focus on IP3R-mediated Ca2+ release from intracellular stores and its role in migration and invasion / Abigael Ritaine, George Shapovalov, Natalia Prevarskaya.

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