Neurotoxicity of metals
In this book, international authorities address contemporary research in metal neurotoxicity. Essential and non-essential metals play an important role in neurodevelopmental and neurodegenerative diseases. Recent developments in understanding the role of metals in the etiology of these disorders hav...
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| Other Authors | , |
|---|---|
| Format | Electronic eBook |
| Language | English |
| Published |
Cham :
Springer,
2017.
|
| Series | Advances in neurobiology ;
18. |
| Subjects | |
| Online Access | Full text |
| ISBN | 9783319601892 9783319601885 |
| Physical Description | 1 online resource |
Cover
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| 245 | 0 | 0 | |a Neurotoxicity of metals / |c Michael Aschner, Lucio G. Costa, editors. |
| 260 | |a Cham : |b Springer, |c 2017. | ||
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a počítač |b c |2 rdamedia | ||
| 338 | |a online zdroj |b cr |2 rdacarrier | ||
| 490 | 1 | |a Advances in neurobiology ; |v v. 18 | |
| 505 | 0 | |a Part I: Developmental Neurotoxicity; Developmental Neurotoxicity of Lead; Introduction; Developmental Exposures to Lead; Neurobehavioral Effects of Lead; Molecular Mechanisms of Neurotoxicity; Developmental Exposures to Lead and Alzheimer's Disease; Conclusions; References; Manganese and Developmental Neurotoxicity; Manganese in the Environment; Airborne Particles; Deposited Dust; Surface Soil; Edible Vegetables; Drinking Water; Toxicology and Biomarkers; Metabolism; Pediatric Absorption; Biomarkers; Effects on Cognitive Functions; Intellectual Ability. | |
| 505 | 8 | |a Executive Function Memory; Academic Achievement; Effects on Motor Functions; Behavior; Attention Deficit Hyperactivity Disorder; Autism Spectrum Disorder; Other Behavioral Outcomes; Effects on Olfactory Function; References; Inherited Disorders of Manganese Metabolism; Introduction; SLC30A10; SLC39A14; SLC39A8; Concluding Perspectives; References; Part II: Neurodegenerative Disorders; Chemical Speciation of Selenium and Mercury as Determinant of Their Neurotoxicity; Introduction; Selenium in the Environment and in the Living Organisms; Selenium: Neurotoxic or Neuroprotector? | |
| 505 | 8 | |a From Selenide to Selenoproteins Selenoproteins in the Brain; Mercury in the Environment and in the Living Organisms; Inorganic Mercury Neurotoxicity; Organic Mercury Neurotoxicity; Selenium and Mercury: Brain Antagonistic Interactions; Selenium as Antagonist of Inorganic Mercury Neurotoxicity; Selenium as an Antagonist of the Neurotoxicity Induced by Organic Mercury; Conclusion; References; Metals and Paraoxonases; Introduction; PON1; Human Polymorphisms of PON1 and Definition of PON1 Status; Modulation of PON1 Activity and Expression; PON2. | |
| 505 | 8 | |a PON2 as an Intracellular Antioxidant Enzyme Modulation of PON2; PON3: Activity, Polymorphisms, Physiological Functions, and Modulation; Interactions of Metals with PONs; In Vitro Effects of Metals on PONs; Effects of Metals on PONs: Animal Studies; Metals and PONs: Human Studies; Lead; Arsenic; Methylmercury and Selenium; Cadmium; Other Metals; Potential Mechanisms of PON1 Modulation by Metals; Summary and Conclusions; References; Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders; Introduction. | |
| 505 | 8 | |a IIS Signaling and Its Role in the Brain Mn and Insulin/IGF Homeostasis; HD Pathobiology; Mn Dysregulation in HD; IIS Dysregulation in HD; Autophagy Deficits in HD, Potential Links to Mn and IIS; Mitochondrial Pathology in HD, Possible Links to Mn and IIS; IIS Signaling and Mn in Other NDDs; PD and IIS/Mn; AD and IIS/Mn; ALS and IIS/Mn; Autophagy in Other Neurodegenerative Diseases; Manganese Toxicity and IGF; The Co-regulation of ATM, Mn, and Insulin/IGF; IIS Signaling, Mn, and Cancer; Conclusions; References; Occupational Metal Exposure and Parkinsonism; Introduction. | |
| 506 | |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty | ||
| 520 | |a In this book, international authorities address contemporary research in metal neurotoxicity. Essential and non-essential metals play an important role in neurodevelopmental and neurodegenerative diseases. Recent developments in understanding the role of metals in the etiology of these disorders have led to rapid growth in clarifying the pathology of some of the most devastating diseases we face and in identifying potential new therapies. Few books or periodicals have been wholly dedicated to the topic of metals, and this collection is intended to serve as a resource for all researchers interested in metals and their role in health and disease. | ||
| 590 | |a SpringerLink |b Springer Complete eBooks | ||
| 650 | 0 | |a Metals |x Toxicology. | |
| 650 | 0 | |a Neurotoxicology. | |
| 655 | 7 | |a elektronické knihy |7 fd186907 |2 czenas | |
| 655 | 9 | |a electronic books |2 eczenas | |
| 700 | 1 | |a Aschner, Michael. |4 edt | |
| 700 | 1 | |a Costa, Lucio. |4 edt | |
| 776 | 0 | 8 | |i Print version: |t Neurotoxicity of metals. |d Cham : Springer, 2017 |z 9783319601885 |z 3319601881 |w (OCoLC)987282561 |
| 830 | 0 | |a Advances in neurobiology ; |v 18. | |
| 856 | 4 | 0 | |u https://proxy.k.utb.cz/login?url=https://link.springer.com/10.1007/978-3-319-60189-2 |
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