Drebrin : from structure and function to physiological and pathological roles

This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as a marker of dementia in neurol...

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Bibliographic Details
Other Authors: Shirao, Tomoaki, (Editor), Sekino, Yuko, (Editor)
Format: eBook
Language: English
Published: Cham, Switzerland : Springer, [2017]
Series: Advances in experimental medicine and biology ; v. 1006.
Subjects:
ISBN: 9784431565505
9784431565482
Physical Description: 1 online resource (xii, 345 pages) : illustrations (chiefly color)

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020 |a 9784431565505  |q (electronic bk.) 
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024 7 |a 10.1007/978-4-431-56550-5  |2 doi 
035 |a (OCoLC)1002857501  |z (OCoLC)1003117723  |z (OCoLC)1003205172  |z (OCoLC)1003253625 
245 0 0 |a Drebrin :  |b from structure and function to physiological and pathological roles /  |c Tomoaki Shirao, Yuko Sekino, editors. 
264 1 |a Cham, Switzerland :  |b Springer,  |c [2017] 
264 4 |c ©2017 
300 |a 1 online resource (xii, 345 pages) :  |b illustrations (chiefly color) 
336 |a text  |b txt  |2 rdacontent 
336 |a statický obraz  |b sti  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
490 1 |a Advances in experimental medicine and biology,  |x 2214-8019 ;  |v volume 1006 
504 |a Includes bibliographical references. 
505 0 |a History of drebrin discovery as an general introduction. General introduction to drebrin / Tomoaki Shirao, Yuko Sekino -- Basic information about drebrin. Molecular cloning of drebrin: progress and perspectives / Nobuhiko Kojima -- Biochemistry of drebrin and its binding to actin filaments / Ryoki Ishikawa -- Phosphorylation of drebrin and its role in neuritogenesis / Phillip R. Gordon-Weeks -- Remodeling of actin filaments by drebrin a and its implications / Elena E. Grintsevich -- Cell shape change by drebrin / Kensuke Hayashi -- Drebrin in nervous system. Localization of drebrin: light microscopy study / Tomoaki Shirao, Noriko Koganezawa, Hiroyuki Yamazaki, Kenji Hanamura, Kazuyuki Imamura -- Making of a synapse: recurrent roles of drebrin a at excitatory synapses throughout life / Chiye Aoki, Ang D. Sherpa -- Drebrin in neuronal migration and axonal growth / Kenji Hanamura -- Drebrin and spine formation / Hideto Takahashi, Yusuke Naito -- Role of drebrin in synaptic plasticity / Yuko Sekino, Noriko Koganezawa, Toshiyuki Mizui, Tomoaki Shirao -- Drebrin in Alzheimer's disease / Yuta Ishizuka, Kenji Hanamura -- Drebrins and connexins: a biomedical perspective / Irina V. Majoul, Justus S. Ernesti, Eugenia V. Butkevich, Rainer Duden -- Homer, spikar, and other drebrin-binding proteins in the brain / Hiroyuki Yamazaki, Tomoaki -- Role of drebrin at the immunological synapse / Vera Rocha-Perugini, Mónica Gordon-Alonso, Francisco Sánchez-Madrid -- Drebrin regulation of calcium signaling in immune cells / Jonathan Pabon, Man Kit Law, Avery August -- Drebrin and spermatogenesis / Haiqi Chen, Michelle W.M. Li, C. Yan Cheng -- Drebrin at junctional plaques / Wiebke K. Ludwig-Peitsch -- Juxtanuclear drebrin-enriched zone / Wiebke K. Ludwig-Peitsch -- Drebrin in renal glomeruli / Wiebke K. Ludwig-Peitsch. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as a marker of dementia in neurological disorders such as Alzheimer's disease. Since drebrin was first identified by our group in 1985, many studies of drebrin have been done in various fields, including not only molecular biology, biophysics, cell biology, neuroscience, clinical studies, spermatogenesis, immunology, and cancer metastasis, but others as well. The structure of this book facilitates the understanding of the whole picture of studies on drebrin. The volume begins with a general introduction to drebrin, and then the chapters in the second part provide the basic knowledge for further understanding. The third part examines its function in the nervous system, and the fourth part discusses its function in the non-nervous system. This work will appeal to researchers who are interested in cytoskeletal dynamics at membrane-cytoskeletal interface as well as the number of them who use drebrin as a tool, such as a marker of synaptic function or a disease marker. This volume is kept as concise as possible in order to be understood by readers in diverse scientific disciplines"--Publisher's description. 
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650 0 |a DNA-binding proteins. 
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655 9 |a electronic books  |2 eczenas 
700 1 |a Shirao, Tomoaki,  |e editor. 
700 1 |a Sekino, Yuko,  |e editor. 
776 0 8 |i Print version:  |t Drebrin.  |d Cham, Switzerland : Springer, [2017]  |z 9784431565482  |w (DLC) 2017951869  |w (OCoLC)981117571 
830 0 |a Advances in experimental medicine and biology ;  |v v. 1006.  |x 0065-2598 
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