Viruses, genes, and cancer

• Other Authors: Hunter, Eric, Bister, Klaus
• Format: Electronic eBook
• Language: English
• Published: [Place of publication not identified] : Springer, 2017.
• Series: Current topics in microbiology and immunology ; v. 104.
• Subjects: Viruses.; Viral genetics.; Genes.; Cancer > Etiology.; elektronické knihy; electronic books
• ISBN: 9783319618043; 9783319618036
• Physical Description: 1 online resource

This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes - such as oncogenes, proto-oncogenes, or tumor supp...

Table of Contents:

• Preface; A Brief Homage to Peter Vogt; Contents; 21 Exchange of Genetic Sequences Between Viruses and Hosts; Abstract; 1 A Year of Virological Anniversaries; 1.1 Bacteriophage and Prokaryote Transduction; 1.2 The Debt of Tumor Virus Research to Phage Genetics; 1.3 Fifty-Five Years of Peter Vogt's Contributions to Retroviruses and Oncogenes; 2 Acquisition of Host Genes by Viruses; 2.1 Oncogenesis by Simple Retroviruses and Transduction of Oncogenes; 2.2 Why Is Retroviral Transduction not a Major Driver of Virus or Host Evolution?
• 2.3 Incorporation of Host Genetic Sequences into Complex Viruses3 Acquisition of Viral Genes by Hosts; 3.1 Viral Genomes in Host DNA: Retroviruses, DNA Viruses and RNA Viruses; 3.2 Evolutionary Dynamics of Exogenous and Endogenous Retroviruses; 3.3 Pathogenic and Beneficial Attributes of Endogenous Retroviruses; 3.4 Role of Endogenous Retroviral Envelopes in the Placenta; 4 Endosymbiont Organelles in Eukaryotic Cells and Their Horizontal Transfer in Cancer; 4.1 Evolution of Complex Cells and Their Organelles; 4.2 Horizontal Spread of Cancer Cells.
• 4.3 Colonization of Cancer Cells by Host Mitochondria5 Concluding Remarks; Acknowledgements; References; 33 Virus-Host Gene Interactions Define HIV-1 Disease Progression; Abstract; 1 Introduction; 2 HIV-1 Transmission; 3 Current Concepts of Genital Tract Infection and Systemic Spread; 4 HIV-1 Transmission is Linked to a Genetic Bottleneck; 5 Evidence for Both Chance and Selection Influencing Transmission; 6 Properties of the Transmitted/Founder Virus; 7 A Complex Interplay Between Host Immunity and Transmitted Virus Phenotype Defines Viral Control and Disease Progression; 8 Conclusions.
• 3 Infectious Agents in Bovine Red Meat and Milk and Their Potential Role in Cancer and Other Chronic DiseasesAbstract; 1 Increased Cancer Risk After Red Meat or Dairy Product Consumption; 2 Risk Reduction for Specific Cancers and Two Chronic Diseases by Long-Time Breast-Feeding; 3 Are Diet-Attributed Factors Increasing Cancer Risks Human-Specific?; 4 Increased Risk for Neurodegenerative Diseases After Red Meat or Dairy Product Consumption; 5 Increased Risk for Cardiovascular or Autoimmune Diseases After Red Meat or Dairy Product Consumption.