Viruses, genes, and cancer

This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes - such as oncogenes, proto-oncogenes, or tumor supp...

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Bibliographic Details
Other Authors: Hunter, Eric., Bister, Klaus.
Format: eBook
Language: English
Published: [Place of publication not identified] : Springer, 2017.
Series: Current topics in microbiology and immunology ; v. 104.
Subjects:
Viruses.
Viral genetics.
Genes.
Cancer > Etiology.
elektronické knihy
electronic books
ISBN: 9783319618043
9783319618036
Physical Description: 1 online resource

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024 7 |a 10.1007/978-3-319-61804-3  |2 doi 
035 |a (OCoLC)1002456935  |z (OCoLC)1002303786  |z (OCoLC)1002822791  |z (OCoLC)1004728754  |z (OCoLC)1023505229  |z (OCoLC)1028111016  |z (OCoLC)1047624906  |z (OCoLC)1048098589  |z (OCoLC)1079836190  |z (OCoLC)1091686443  |z (OCoLC)1113369704  |z (OCoLC)1160093136  |z (OCoLC)1162756390 
245 0 0 |a Viruses, genes, and cancer /  |c Eric Hunter, Klaus Bister, editors. 
260 |a [Place of publication not identified] :  |b Springer,  |c 2017. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
490 1 |a Current topics in microbiology and immunology ;  |v v. 104 
505 0 |a Preface; A Brief Homage to Peter Vogt; Contents; 21 Exchange of Genetic Sequences Between Viruses and Hosts; Abstract; 1 A Year of Virological Anniversaries; 1.1 Bacteriophage and Prokaryote Transduction; 1.2 The Debt of Tumor Virus Research to Phage Genetics; 1.3 Fifty-Five Years of Peter Vogt's Contributions to Retroviruses and Oncogenes; 2 Acquisition of Host Genes by Viruses; 2.1 Oncogenesis by Simple Retroviruses and Transduction of Oncogenes; 2.2 Why Is Retroviral Transduction not a Major Driver of Virus or Host Evolution? 
505 8 |a 2.3 Incorporation of Host Genetic Sequences into Complex Viruses3 Acquisition of Viral Genes by Hosts; 3.1 Viral Genomes in Host DNA: Retroviruses, DNA Viruses and RNA Viruses; 3.2 Evolutionary Dynamics of Exogenous and Endogenous Retroviruses; 3.3 Pathogenic and Beneficial Attributes of Endogenous Retroviruses; 3.4 Role of Endogenous Retroviral Envelopes in the Placenta; 4 Endosymbiont Organelles in Eukaryotic Cells and Their Horizontal Transfer in Cancer; 4.1 Evolution of Complex Cells and Their Organelles; 4.2 Horizontal Spread of Cancer Cells. 
505 8 |a 4.3 Colonization of Cancer Cells by Host Mitochondria5 Concluding Remarks; Acknowledgements; References; 33 Virus-Host Gene Interactions Define HIV-1 Disease Progression; Abstract; 1 Introduction; 2 HIV-1 Transmission; 3 Current Concepts of Genital Tract Infection and Systemic Spread; 4 HIV-1 Transmission is Linked to a Genetic Bottleneck; 5 Evidence for Both Chance and Selection Influencing Transmission; 6 Properties of the Transmitted/Founder Virus; 7 A Complex Interplay Between Host Immunity and Transmitted Virus Phenotype Defines Viral Control and Disease Progression; 8 Conclusions. 
505 8 |a 3 Infectious Agents in Bovine Red Meat and Milk and Their Potential Role in Cancer and Other Chronic DiseasesAbstract; 1 Increased Cancer Risk After Red Meat or Dairy Product Consumption; 2 Risk Reduction for Specific Cancers and Two Chronic Diseases by Long-Time Breast-Feeding; 3 Are Diet-Attributed Factors Increasing Cancer Risks Human-Specific?; 4 Increased Risk for Neurodegenerative Diseases After Red Meat or Dairy Product Consumption; 5 Increased Risk for Cardiovascular or Autoimmune Diseases After Red Meat or Dairy Product Consumption. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes - such as oncogenes, proto-oncogenes, or tumor suppressor genes - in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment. Gathering contributions written by leading scientists in their respective fields, the volume offers a valuable resource for researchers and clinicians alike. 
504 |a Includes bibliographical references. 
590 |a SpringerLink  |b Springer Complete eBooks 
650 0 |a Viruses. 
650 0 |a Viral genetics. 
650 0 |a Genes. 
650 0 |a Cancer  |x Etiology. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Hunter, Eric. 
700 1 |a Bister, Klaus. 
776 0 8 |i Print version:  |t Viruses, genes, and cancer.  |d [Place of publication not identified] : Springer, 2017  |z 3319618032  |z 9783319618036  |w (OCoLC)988280158 
830 0 |a Current topics in microbiology and immunology ;  |v v. 104. 
856 4 0 |u https://proxy.k.utb.cz/login?url=https://link.springer.com/10.1007/978-3-319-61804-3  |y Plný text 
992 |c NTK-SpringerBLS 
999 |c 97478  |d 97478 

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