Personalised medicine : lessons from neurodegeneration to cancer

"The mammalian genome is constantly challenged by exogenous and endogenous threats. Although much is known about the mechanisms that maintain genome integrity, little is known about the applications of this knowledge to combat human disease. The past 20 years has witnessed extensive research an...

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Bibliographic Details
Other Authors El-Khamisy, Sherif (Editor)
Format Electronic eBook
LanguageEnglish
Published Cham, Switzerland : Springer, [2017]
SeriesAdvances in experimental medicine and biology ; v. 1007.
Subjects
Online AccessFull text
ISBN9783319607337
9783319607313
ISSN2214-8019 ;
Physical Description1 online resource (viii, 260 pages) : illustrations (some color)

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Table of Contents:
  • Approaches for identifying novel targets in precision medicine: lessons from DNA repair / Dean T. Williams, Christopher J. Staples
  • Nucleotide excision repair: from neurodegeneration to cancer / Anastasios Liakos, Matthieu D. Lavigne, Maria Fousteri
  • Role of protein linked DNA breaks in cancer / Walaa R. Allam, Mohamed E. Ashour, Amr A. Waly, Sherif El-Khamisy
  • The emerging role of proteomics in precision medicine: applications in neurodegenerative diseases and neurotrauma / Rana Alaaeddine, Mira Fayad, Eliana Nehme, Hisham F. Bahmad, Firas Kobeissy
  • The role of nitric oxide from neurological disease to cancer / Ahmed Maher, Mohamed F. Abdel Rahman, Mohamed Z. Gad
  • RNA nuclear export: from neurological disorders to cancer / Guillaume M. Hautbergue
  • Can astrocytes be a target for precision medicine? / Chloe F. Allen, Pamela J. Shaw, Laura Ferraiuolo
  • Mitochondrial diseases as model of neurodegeneration / Laila A. Selim, Heba Hassaan
  • Personalised medicine: genome maintenance lessons learned from studies in yeast as a model organism / Arwa A. Abugable, Dahlia A. Awwad, Dalia Fleifel, Mohamed M. Ali, Sherif El-Khamisy [and others]
  • The power of zebrafish in personalised medicine / Sarah Baxendale, Freek van Eeden, Robert Wilkinson
  • Personalized medicine and resurrected hopes for the management of Alzheimer's disease: a modular approach based on GSK-3[beta] inhibitors / Reem K. Arafa, Nehal H. Elghazawy
  • Regenerative medicine: advances from developmental to degenerative diseases / Nicholas F. Blair, Thomas J.R. Frith, Ivana Barbaric
  • Gene therapy in the nervous system: failures and successes / Jayanth S. Chandran, Joseph M. Scarrott, Pamela J. Shaw, Mimoun Azzouz.