Hormones in ageing and longevity
This multi-chapter book focuses on one of the hottest topics in ageing research - the role of hormones in health and longevity, offering a comprehensive and up-to-date overview of their mechanistic roles in health, ageing and longevity. Hormones are an excellent system of communication between cells...
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| Other Authors: | , |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
Cham :
Springer,
[2017]
|
| Series: | Healthy ageing and longevity ;
v. 6. |
| Subjects: | |
| ISBN: | 9783319630014 9783319630007 |
| Physical Description: | 1 online resource |
Cover
Table of contents
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| 245 | 0 | 0 | |a Hormones in ageing and longevity / |c Suresh Rattan, Ramesh Sharma, editors. |
| 260 | |a Cham : |b Springer, |c [2017] | ||
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a počítač |b c |2 rdamedia | ||
| 338 | |a online zdroj |b cr |2 rdacarrier | ||
| 490 | 1 | |a Healthy ageing and longevity ; |v v. 6 | |
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |6 880-01 |a Preface; Contents; History and Conflux; 1 How Hormones, as Ancient Signalling Molecules, Regulate Diverse Biological Processes Through Evolution; Abstract; 1.1 Introduction; 1.2 Evolution: Hormones Are Messengers but Do not Carry Any Information; 1.3 Environmental Cues and Endocrine Cascades; 1.4 Receptors: Key to the Understanding of the Mechanism of Hormone Action; 1.5 Membrane Receptors; 1.6 Nuclear Receptors; 1.7 Chromatin Structure and Hormonal Regulation; 1.8 Integration of the Membrane- and Nuclear Receptor-Linked Hormonal Pathways; 1.9 Hormones and Their Actions Through Evolution. | |
| 505 | 8 | |a 3.2 Glucocorticoid Cascade Hypothesis3.2.1 Glucocorticoids in Health; 3.2.2 Glucocorticoids in Clinical Science; 3.2.3 Glucocorticoids Side Effects; 3.3 Glucocorticoids in Aging; 3.3.1 Glucocorticoids, HPA Axis and Aging; 3.3.2 Glucocorticoids Extra- and Intra-cellular Bioavailability with Age; 3.3.3 Glucocorticoids Genomic Signaling as a Function of Age; 3.3.4 Glucocorticoids Non-genomic Signaling in Aging; 3.4 Management of Glucocorticoids Induced Age-Related Complications via GR Signaling Pathway Modulation; 3.5 Conclusion; Acknowledgements; References. | |
| 505 | 8 | |a 4 Zinc, Insulin and IGF-I Interplay in AgingAbstract; 4.1 Introduction; 4.2 Biological Functions of Zn; 4.3 Zinc in Biogerontology; 4.3.1 Zn Supplements and Longevity; 4.3.2 Zn Regulatory Mechanisms and Longevity; 4.4 Zinc Insulin Interplay; 4.4.1 Zinc Action on Insulin Activity; 4.4.2 Influence of Zinc Machinery on Insulin Activity; 4.4.3 Insulin Action on Zn Homeostasis; 4.5 Zinc IGF-1 Interplay; 4.5.1 Modulation of IGF-1 Action by Zn Signals; 4.5.2 Modulation of Zn Homeostasis by IGF-1; 4.6 Conclusions; References; Supplementary Data; Human:; Mus Musculus. | |
| 505 | 8 | |a 5 Growth Hormone and IGF-1 Axis in Aging and LongevityAbstract; 5.1 Introduction; 5.2 Decline of the GH-IGF-1 Axis and Replacement Therapy in Elderly People; 5.3 Loss-of- or Reduction-of Function Mutations of Genes in the GH Signal Transduction Pathway Consistently Extend Lifespan in a Range of Experimental Animals; 5.4 Lifespan Extension by Single Gene Mutations Related to the Reduction of the GH-IGF-1 Axis; 5.5 Genes Downstream of IGF-1 Signaling that Lead to Lifespan Extension; 5.6 Evidence in Humans Indicating a Relation Between Longevity and Inhibition of the GH-IGF-1 Axis. | |
| 506 | |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty | ||
| 520 | |a This multi-chapter book focuses on one of the hottest topics in ageing research - the role of hormones in health and longevity, offering a comprehensive and up-to-date overview of their mechanistic roles in health, ageing and longevity. Hormones are an excellent system of communication between cells and tissues within an organism, and they coordinate a wide range of processes in biological systems, including neuroendocrine and immunological controls. The book offers insights into the latest significant advances in our understanding of the mechanisms of hormonal signaling that control a variety of processes involved in development and ageing. It is divided into four parts: Part I includes a review of the hundred-year history of hormones by the illustrious hormone biochemist Dr. J.R. Tata. Part II presents various chapters on the hormones involved in growth, stress and metabolism, while Part III addresses the hormones controlling cognition and rhythms in ageing processes. Lastly, Part IV discusses the hormones affecting reproduction, immunity and life span. It also explores the use of hormones as pharmaceuticals to maintain health in the elderly. It is a valuable resource for those working in the area of hormone signaling in general and in the field of ageing research in particular. | ||
| 590 | |a SpringerLink |b Springer Complete eBooks | ||
| 650 | 0 | |a Longevity. | |
| 650 | 0 | |a Aging |x Hormone therapy. | |
| 650 | 0 | |a Hormones. | |
| 655 | 7 | |a elektronické knihy |7 fd186907 |2 czenas | |
| 655 | 9 | |a electronic books |2 eczenas | |
| 700 | 1 | |a Rattan, Suresh I. S., |e editor. | |
| 700 | 1 | |a Sharma, Ramesh, |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Hormones in ageing and longevity. |d Cham : Springer, [2017] |z 9783319630007 |z 3319630008 |w (OCoLC)992747905 |
| 830 | 0 | |a Healthy ageing and longevity ; |v v. 6. | |
| 856 | 4 | 0 | |u https://proxy.k.utb.cz/login?url=https://link.springer.com/10.1007/978-3-319-63001-4 |y Plný text |
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| 999 | |c 97472 |d 97472 | ||
| 993 | |x NEPOSILAT |y EIZ | ||
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