Future directions in metalloprotein and metalloenzyme research

This book covers the latest developments in metalloenzymes, including characterizing metal bridging in proteins and peptides, copper(II) complexes of marine peptides, high-spin Co(II) in model and metalloprotein systems to enzymes such as the molybdenum-containing enzymes, CW and pulse EPR of cytoch...

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Bibliographic Details
Other Authors Hanson, Graeme, 1955-2015, Berliner, Lawrence J.
Format Electronic eBook
LanguageEnglish
Published Cham : Springer, 2017.
SeriesBiological magnetic resonance ; v. 33.
Subjects
Online AccessFull text
ISBN9783319591001
9783319590981
ISSN0192-6020 ;
Physical Description1 online resource

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245 0 0 |a Future directions in metalloprotein and metalloenzyme research /  |c Graeme Hanson, Lawrence Berliner, editors. 
260 |a Cham :  |b Springer,  |c 2017. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
490 1 |a Biological magnetic resonance,  |x 0192-6020 ;  |v v. 33 
500 |a Includes index. 
505 0 |a Dedication; Preface; Contents; An Isotopic Dilution Strategy for Characterisation of Paramagnetic Metal Bridging of Proteins and Peptides; Introduction; Isotopic Labelling to Determine the First Coordination Sphere; Isotopic Dilution to Identify Metal-Bridged Peptide Oligomers; Methods; Experimental Preparation; Numerical Simulation; Examples; References; Structures, Electronics and Reactivity of Copper(II) Complexes of the Cyclic Pseudo-ƯPeptides of the Ascidians; Background; Prochloron: A Special Cyanobacterium; Ribosomal Expression of Cyclic Peptides. 
505 8 |a Metal Complexes of Cyclic Hexa- and Octapeptides Model Peptides; CuII and ZnII Coordination Chemistry of Westiellamide and Patellamide Derivatives: Solution Equilibria and Structures; In vitro Reactivity of Dinuclear Patellamide Complexes; Preliminary In vivo Studies of Patellamide Complexes; Conclusion and Outlook; References; Paramagnetic Resonance of High-Spin Co(II) in Biologically-Relevant Environments: Models to Metalloproteins; Introduction; Electronic Structure of High-Spin Co(II); Translation to EPR Properties and ZFS in High-Spin Co(II); Examples. 
505 8 |a Four- and Five-Coordinate Pyrazolylborates Parallel Mode EPR of Mononuclear Co(II) Complexes; ENDOR of Six-Coordinate Trigonal Co(II); Prospects for Pulsed EPR; Summary; References; EPR Spectroscopy on Mononuclear Molybdenum-Containing Enzymes; Introduction; An Overview on Molybdenum-Containing Enzymes; EPR Studies of Molybdoenzymes; Xanthine Oxidase Family; The Enzymes; EPR Studies of Mammalian Xanthine Oxidase; The "Very Rapid" Signal; The "Rapid" Signals; The "Slow" Signal; Signals Obtained From Inhibited and Inactive Forms of Xanthine Oxidase. 
505 8 |a Magnetic Interactions Within Xanthine Oxidase EPR Studies of Desulfovibrio Aldehyde Oxidoreductase; EPR Studies of Nicotinate Dehydrogenase and Carbon Monoxide Dehydrogenase; Sulfite Oxidase Family; The Enzymes; EPR Studies of Vertebrate Sulfite Oxidase; The "Low pH" Signal; The "High pH" Signal; The Family of "Oxo-Anion" Signals; Dimethylsulfoxide Reductase Family; The Enzymes; EPR Studies of Formate Dehydrogenases; EPR Studies of Nitrate Reductases; Periplasmatic Nitrate Reductases Signals; Assimilatory Nitrate Reductases Signals; Respiratory Nitrate Reductases Signals. 
505 8 |a Concluding RemarksReferences; CW and Pulse EPR of Cytochrome P450 to Determine Structure and Function; Introduction; Basic EPR Theory for Cytochromes P450; Interpretation of EPR Data Aided by Quantum Chemical Calculations; CW EPR to Characterise the Resting State and Substrate Bound P450 Active Site; Extracting Spin-State from g-Values and Its Relation to Optical and MCD Spectroscopy; The g-Values as an Indicator for Substrate Interactions; High-Resolution Pulsed EPR to Characterise the Resting State and Substrate Bound P450 Active Site. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This book covers the latest developments in metalloenzymes, including characterizing metal bridging in proteins and peptides, copper(II) complexes of marine peptides, high-spin Co(II) in model and metalloprotein systems to enzymes such as the molybdenum-containing enzymes, CW and pulse EPR of cytochrome P450 enzymes and the radical S-adenosylmethionine FeS family. In the previous two related volumes in the Biological Magnetic Resonance series, High-Resolution EPR: Applications to Metalloenzymes and Metals in Medicine and Metals in Biology:Applications of High-Resolution EPR to Metalloenzymes, topics covered included high-resolution EPR methods, iron proteins, nickel and copper enzymes, metals in medicine, iron-sulfur cluster-containing proteins, and molybdenum enzymes. In this volume, new developments in these areas are covered in detail and new areas that have emerged are also detailed. This is an ideal book for graduate students and researchers working in the fields of high-resolution EPR, metalloenzymes, and metals in biology. 
590 |a SpringerLink  |b Springer Complete eBooks 
650 0 |a Metalloproteins. 
650 0 |a Metalloenzymes. 
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700 1 |a Hanson, Graeme,  |d 1955-2015. 
700 1 |a Berliner, Lawrence J. 
776 0 8 |i Print version:  |z 9783319590981  |z 3319590987  |w (OCoLC)985082355 
830 0 |a Biological magnetic resonance ;  |v v. 33. 
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