Neurodegenerative diseases : pathology, mechanisms, and potential therapeutic targets

Provides a timely overview of critical advances in molecular and cellular neurobiology, covers key methodologies driving progress, and highlights key future directions for research on neuronal injury and neurodegeneration relevant to neuronal brain pathologies. The editors bring together contributio...

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Bibliographic Details
Other Authors Beart, P. M. (Editor), Robinson, Michael (Editor), Rattray, Marcus (Editor), Maragakis, Nicholas J. (Editor)
Format Electronic eBook
LanguageEnglish
Published Cham, Switzerland : Springer, 2017.
SeriesAdvances in neurobiology ; 15.
Subjects
Nervous system > Degeneration.
elektronické knihy
electronic books
Online AccessFull text
ISBN9783319571935
9783319571911
ISSN2190-5215 ;
Physical Description1 online resource (xiv, 542 pages) : illustrations (some color)

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Table of Contents:
  • Part 1: Major Neurodegenerative Conditions
  • Alzheimer's Disease
  • Insights from Genetic Mouse Models and Current Advances in Human IPSC-Derived Neurons
  • Clinical Aspects of Alzheimer's Disease
  • Parkinson's Disease: Basic Pathomechanisms and a Clinical Overview
  • Huntington's Disease: Pathogenic Mechanisms and Therapeutic Targets
  • The Complexity of Clinical Huntington's Disease: Developments in Molecular Genetics, Neuropathology and Neuroimaging Biomarkers
  • Motoneurone Disease
  • Basic Science
  • Motoneurone Disease
  • Clinical
  • Multiple Sclerosis
  • Basic and Clinical
  • Part 2: Other Neurological Conditions
  • Schizophrenia--Basic and Clinical
  • Stroke
  • Basic and Clinical
  • Epileptic Encephalopathies as Neurodegenerative Disorders
  • Neurodegeneration and Pathology in Epilepsy-Clinical and Basic Perspectives
  • Prion Disease
  • Basic and Clinical
  • Leukodystrophies
  • Basic and Clinical
  • Traumatic Brain Injury as a Trigger of Neurodegeneration
  • Part 3: Key Background and Key Technologies
  • Cell Death Mechanisms of Neurodegeneration
  • Neuroglia: Functional Paralysis and Reactivity in Alzheimer's Disease and Other Neurodegenerative Pathologies
  • Advances in Neuroimaging for Neurodegenerative Disease
  • Gene Linkage and Systems Biology
  • Biomarkers in Neurodegenerative Diseases.

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