Neurodegenerative diseases : pathology, mechanisms, and potential therapeutic targets

Provides a timely overview of critical advances in molecular and cellular neurobiology, covers key methodologies driving progress, and highlights key future directions for research on neuronal injury and neurodegeneration relevant to neuronal brain pathologies. The editors bring together contributio...

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Bibliographic Details
Other Authors: Beart, P. M. (Editor), Robinson, Michael, (Editor), Rattray, Marcus, (Editor), Maragakis, Nicholas J., (Editor)
Format: eBook
Language: English
Published: Cham, Switzerland : Springer, 2017.
Series: Advances in neurobiology ; 15.
Subjects:
Nervous system > Degeneration.
elektronické knihy
electronic books
ISBN: 9783319571935
9783319571911
Physical Description: 1 online resource (xiv, 542 pages) : illustrations (some color)

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020 |a 9783319571935  |q (electronic bk.) 
020 |z 9783319571911  |q (print) 
024 7 |a 10.1007/978-3-319-57193-5  |2 doi 
035 |a (OCoLC)992988868  |z (OCoLC)993594835  |z (OCoLC)1002396361  |z (OCoLC)1005824752  |z (OCoLC)1011849874  |z (OCoLC)1048096711  |z (OCoLC)1066505980  |z (OCoLC)1066658622  |z (OCoLC)1113167556  |z (OCoLC)1116046051  |z (OCoLC)1122813725  |z (OCoLC)1160018534  |z (OCoLC)1162782141 
245 0 0 |a Neurodegenerative diseases :  |b pathology, mechanisms, and potential therapeutic targets /  |c Philip Beart, Michael Robinson, Marcus Rattray, Nicholas J. Maragakis, editors. 
264 1 |a Cham, Switzerland :  |b Springer,  |c 2017. 
300 |a 1 online resource (xiv, 542 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
490 1 |a Advances in neurobiology,  |x 2190-5215 ;  |v volume 15 
500 |a Includes index. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a Provides a timely overview of critical advances in molecular and cellular neurobiology, covers key methodologies driving progress, and highlights key future directions for research on neuronal injury and neurodegeneration relevant to neuronal brain pathologies. The editors bring together contributions from internationally recognized workers in the field to provide an up to date account of how and why molecular and cellular neurobiology is such an important area for clinical neuroscience. Understanding the molecular aspects of a number of neurodegenerative conditions such as Parkinson's or Alzheimer's disease for the purpose of improving patient management remains a major challenge of neurobiology be it from the basic or clinical perspective. A strategic evaluation of research contributions and the power of modern methods will help advance knowledge over the next years. 
505 0 |a Part 1: Major Neurodegenerative Conditions -- Alzheimer's Disease -- Insights from Genetic Mouse Models and Current Advances in Human IPSC-Derived Neurons -- Clinical Aspects of Alzheimer's Disease -- Parkinson's Disease: Basic Pathomechanisms and a Clinical Overview -- Huntington's Disease: Pathogenic Mechanisms and Therapeutic Targets -- The Complexity of Clinical Huntington's Disease: Developments in Molecular Genetics, Neuropathology and Neuroimaging Biomarkers -- Motoneurone Disease -- Basic Science -- Motoneurone Disease -- Clinical -- Multiple Sclerosis -- Basic and Clinical -- Part 2: Other Neurological Conditions -- Schizophrenia--Basic and Clinical -- Stroke -- Basic and Clinical -- Epileptic Encephalopathies as Neurodegenerative Disorders -- Neurodegeneration and Pathology in Epilepsy-Clinical and Basic Perspectives -- Prion Disease -- Basic and Clinical -- Leukodystrophies -- Basic and Clinical -- Traumatic Brain Injury as a Trigger of Neurodegeneration -- Part 3: Key Background and Key Technologies -- Cell Death Mechanisms of Neurodegeneration -- Neuroglia: Functional Paralysis and Reactivity in Alzheimer's Disease and Other Neurodegenerative Pathologies -- Advances in Neuroimaging for Neurodegenerative Disease -- Gene Linkage and Systems Biology -- Biomarkers in Neurodegenerative Diseases. 
590 |a SpringerLink  |b Springer Complete eBooks 
650 0 |a Nervous system  |x Degeneration. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Beart, P. M.  |q (Philip M.),  |e editor. 
700 1 |a Robinson, Michael,  |e editor. 
700 1 |a Rattray, Marcus,  |e editor. 
700 1 |a Maragakis, Nicholas J.,  |e editor. 
776 0 8 |i Printed edition:  |z 9783319571911 
830 0 |a Advances in neurobiology ;  |v 15. 
856 4 0 |u https://proxy.k.utb.cz/login?url=https://link.springer.com/10.1007/978-3-319-57193-5  |y Plný text 
992 |c NTK-SpringerBLS 
999 |c 97411  |d 97411 
993 |x NEPOSILAT  |y EIZ 

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