RNA activation

This book offers an essential guide to RNA activation (RNAa), an emerging and fascinating new field. RNAa is a small RNA-guided and Argonaute-dependent gene regulation phenomenon in which promoter-targeted short double-stranded RNAs (dsRNAs) induce target gene expression at the transcriptional level...

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Bibliographic Details
Other Authors Li, Long-Cheng (Editor)
Format Electronic eBook
LanguageEnglish
Published Singapore : Springer, [2017]
SeriesAdvances in experimental medicine and biology ; v. 983.
Subjects
RNA.
Gene expression.
elektronické knihy
electronic books
Online AccessFull text
ISBN9789811043109
9789811043093
ISSN2214-8019 ;
Physical Description1 online resource : illustrations (chiefly color)

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Table of Contents:
  • Small RNA-guided transcriptional gene activation (rnaa) in mammalian cells / Long-Cheng Li / Exogenous RNAa. Enhancing neuronogenesis and counteracting neuropathogenic gene haploinsufficiencies by RNA gene activation / Antonello Mallamaci
  • Target-recognition mechanism and specificity of RNA activation / Huiqing Cao, Xing Meng, Xiaoxia Wang, Zicai Liang
  • Promoter-targeted small activating rnas alter nucleosome positioning / Bin Wang, Yunzhang Hu
  • Endogenous RNAa. Endogenous miRNAa: miRNA-mediated gene upregulation / Vera Huang
  • Mirna-mediated RNA activation in mammalian cells / Ramani Ramchandran, Pradeep Chaluvally-Raghavan
  • RNAa induced by tata box-targeting micrornas / Yijun Zhang, Hui Zhang
  • miRNA-mediated RNAa by targeting enhancers / Qingping Zou, Ying Liang, Huaibing Luo, Wenqiang Yu
  • RNA activation guided by other RNA. specific increase of protein levels by enhancing translation using antisense oligonucleotides targeting upstream open frames / Xue-Hai Liang, Wen Shen, Stanley T. Crooke
  • Repurposing CRISPR system for transcriptional activation / Meng Chen, Lei Stanley Qi
  • Developing RNAa-based therapeutics. RNA-mediated gene activation: identifying a candidate RNA for preclinical development / David R. Corey
  • Treatment of pancreatic cancer by aptamer conjugated C/EBP[alpha]-saRNA / Sorah Yoon, John J. Rossi
  • Treatment of liver cancer by C/EBPA saRNA / Xiaoyang Zhao, Jon Voutila, Stephanos Ghobrial, Nagy A. Habib, Vikash Reebye
  • Enhancing angiogenesis in mice by VEGF-targeting small activating RNAs / Tiia A. Turunen, Seppo Ylä-Herttuala, Mikko P. Turunen
  • Suppression of prostate cancer metastasis by DPYSL3-targeted saRNA / Benyi Li, Changlin Li
  • Development of therapeutic dsP21 for cancer treatment / Moo Rim Kang, Gongcheng Li, Tiejun Pan, Jin-Chun Xing, Long-Cheng Li.

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