Cell division machinery and disease

"This book critically evaluates the causal link between cell division machinery and disease. Further, it identifies key open questions in the field and the means for exploring them. Throughout the various chapters, internationally known contributors present the evidence for and against a causal...

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Bibliographic Details
Other Authors Gotta, Monica (Editor), Meraldi, Patrick (Editor)
Format Electronic eBook
LanguageEnglish
Published Cham, Switzerland : Springer, [2017]
SeriesAdvances in experimental medicine and biology ; 1002.
Subjects
Online AccessFull text
ISBN9783319571270
9783319571256
ISSN2214-8019 ;
Physical Description1 online resource (xiv, 235 pages) : color illustrations

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Table of Contents:
  • Meiotic divisions: no place for gender equality / Warif El Yakoubi, Katja Wassmann
  • Consequences of centrosome dysfunction during brain development / Maddalena Nano, Renata Basto
  • Dividing with extra centrosomes: a double edged sword for cancer cells / Alexander D. Rhys, Susana A. Godinho
  • Kinetochore malfunction in human pathologies / Bas de Wolf, Geert J.P.L. Kops
  • The elephant in the room: the role of microtubules in cancer / Luca Cirillo, Monica Gotta, Patrick Meraldi
  • Clinical development of anti-mitotic drugs in cancer / Anna-Maria Olziersky, S. Intidhar Labidi-Galy
  • Mitotic dysfunction associated with aging hallmarks / Joana Catarina Macedo, Sara Vaz, Elsa Logarinho
  • Unbalanced growth, senescence and aging / Michael Polymenis, Brian K. Kennedy
  • The spindle orientation machinery beyond mitosis: when cell specialization demands polarization / Abigail L.D. Tadenev, Basile Tarc.