Patient-specific hemodynamic computations : application to personalized diagnosis of cardiovascular pathologies

• Other Authors: Itu, Lucian Mihai, Sharma, Puneet, Suciu, Constantin
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer, 2017.
• Subjects: Cardiovascular system > Diseases > Diagnosis.; elektronické knihy; electronic books
• ISBN: 9783319568539; 9783319568522
• Physical Description: 1 online resource (232 pages)

Hemodynamic computations represent a state-of-the-art approach for patient-specific assessment of cardiovascular pathologies. The book presents the development of reduced-order multiscale hemodynamic models for coronary artery disease, aortic coarctation and whole body circulation, which can be appl...

Table of Contents:

• Preface; Contents; Contributors; 1: Computational Modeling of the Human Cardiovascular System; 1.1 Introduction; 1.2 Multiscale Modeling of Arterial Hemodynamics; 1.3 Patient-Specific Multiscale Modeling of Arterial Hemodynamics; 1.4 Parallel Processing in Multiscale Hemodynamic Modeling; References; 2: The Cardiovascular System and the Coronary Circulation; 2.1 The Cardiovascular System; 2.2 The Anatomy of the Coronary Arteries; 2.2.1 Right Coronary Anatomy; 2.2.2 Left Coronary Anatomy; 2.2.2.1 Left Main Coronary Artery; 2.2.2.2 Left Anterior Descending Artery.
• 2.2.2.3 The Circumflex Artery2.2.3 Determination of Dominance; 2.2.4 Frequent Coronary Artery Variants; 2.2.5 Angiography of the Coronary Vessels; 2.3 Coronary Artery Disease; 2.3.1 Pathophysiology of Coronary Artery Disease; 2.3.1.1 Atherosclerotic Risk Factors; 2.3.1.2 Pathophysiology of Coronary Artery Disease; Regulation of Coronary Blood Flow; Atherosclerotic Plaque Formation; 2.3.1.3 Pathophysiology of Stable Angina (Stress Induced Angina); 2.3.1.4 Pathophysiology Behind the Acute Coronary Syndromes; 2.3.1.5 Plaque Vulnerability.
• 2.3.1.6 Clinical Significance of Atherosclerotic Disease2.3.2 Diagnostic Imaging in Coronary Artery Disease: Echocardiography Studies; 2.3.2.1 Basic Principles of Echocardiography in Coronary Artery Disease; 2.3.2.2 The Importance of Echocardiography in Patients with Coronary Artery Disease; Differential Diagnosis of Chest Pain; Diastolic Dysfunction in Ischemic Heart Disease; Global and Regional Systolic Left Ventricular Functional Changes in Coronary Artery Disease; 2.3.3 Invasive Diagnosis of Coronary Artery Disease: Angiography; 2.3.3.1 The Coronary Angiography.
• 2.3.3.2 Percutaneous Coronary Interventions2.3.3.3 Indications of Coronary Angiography and PCI; 2.3.3.4 Adjunctive Invasive Diagnostic Tools; 2.4 Aortic Pathologies; 2.4.1 Background; 2.4.2 Anatomy, Physiology and Physiopathology; 2.4.3 Natural History and Clinical Presentation; 2.4.4 Diagnostic Work-Up; 2.4.4.1 Chest Radiography; 2.4.4.2 Electrocardiography; 2.4.4.3 Echocardiography; 2.4.4.4 Magnetic Resonance Imaging; 2.4.4.5 Diagnostic Cardiac Catheterization and Angiography; 2.4.5 Management of Coarctation of the Aorta; 2.4.6 Long Term Prognosis; References.
• 3: Patient-Specific Modeling of the Coronary Circulation3.1 Introduction; 3.2 Instantaneous Wave-Free Ratio; 3.3 Methods; 3.3.1 Rest State Flow Rate Estimation; 3.3.2 Computational Blood Flow Modeling; 3.3.3 Clinical Data; 3.3.4 Evaluation of a Hybrid c-IFR-FFR strategy; 3.4 Results; 3.4.1 Detailed Results for a Subset of Cases; 3.5 Discussion and Conclusions; References; 4: A Parameter Estimation Framework for Patient-Specific Assessment of Aortic Coarctation; 4.1 Introduction; 4.2 Methods; 4.2.1 Calibration Method for Windkessel Parameters.