rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Epigenetics of infectious diseases
  name:
    name part: Doerfler, Walter
    name part: 1933-
  name:
    name part: Casadesús, Josep
    name part: 1951-
  type of resource: text
  genre: bibliography
  genre: elektronické knihy
  genre: electronic books
  origin info:
    place:
      place term: sz
    place:
      place term: Cham
    publisher: Springer
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource
  abstract: The present volume of Epigenetics and Human Health is devoted to the patho-epigenetics of viral and microbial infections, an exiting new field of disease-related epigenetic research. As recognized during the past years, epigenetic reprogramming of pathogen and host genome functions - the latter frequently induced by pathogens - plays an important role in many infectious processes. Beyond their immediate relevance for pathogen proliferation and obligatorily associated symptoms, such alterations frequently contribute to severe additional complications, such as the development of immunodeficiency, cancer and various chronic disorders. This holds in particular for epigenetic dysregulation of host gene expression induced by latent infections. The present book summarizes current knowledge of the mechanisms underlying epigenetic changes caused by viral, bacterial, fungal and protozoan infections and their impact on human health.
  table of contents: Preface; Contents; Chapter 1: DNA Methylation of Human Papillomavirus Genomes During Infection and Cancer Progression; 1.1 Introduction; 1.2 History of Papillomavirus Methylation Research; 1.3 Methylation of HPV DNA During the Normal Life Cycle; 1.3.1 In Summary; 1.4 Regulatory Effects of DNA Methylation via CpG Dinucleotides in E2 Binding Sites; 1.5 Effects of Papillomaviruses on the Cellular Epigenome; 1.6 Differential Methylation of HPV Genomes in Malignant Lesions; 1.7 HPV Epigenomes and Cellular Epigenomic Properties of HPV Infected Cells as Cancer Biomarkers; References.
  table of contents: Chapter 2: Epigenetic Regulation of Gammaherpesviruses: A Focus on Kaposiś Sarcoma-Associated Herpesvirus (KSHV/HHV-8)2.1 Introduction; 2.1.1 Genome Organization and Circularization; 2.1.2 Gene Expression During Latency; 2.1.3 Gene Expression During Lytic Phase; 2.2 Histone Modifications; 2.2.1 Histone Modifications During Gammaherpesvirus Latency; 2.2.2 Histone Modifications During Lytic Reactivation; 2.2.3 Intra- and Inter-locus Epigenetic Heterogeneity in KSHV Episomes; 2.3 DNA Methylation; 2.4 Chromatin Organization by CTCF and the Cohesin Complex.
  table of contents: 2.5 Noncoding RNAs and Epigenetic Control2.6 Conclusions; References; Chapter 3: Discoveries in Molecular Genetics with the Adenovirus 12 System: Integration of Viral DNA and Epigenetic Consequenc ... ; 3.1 Background on Interest in DNA Methylation and Epigenetic Effects; 3.1.1 Introduction to the Adenovirus System; 3.1.1.1 Ad12-Syrian Hamster Cells: The Abortive System; 3.1.2 Foreign DNA in the Environment; 3.1.3 Biology of Ad12-Induced Hamster Tumors; 3.1.4 Characteristics of Chromosomally Integrated Adenovirus DNA.
  table of contents: 3.1.5 The Consequences of Inserting Foreign DNA into Established Mammalian Genomes3.1.5.1 Hypermethylation of Integrated Ad12 DNA, the Transgenome; 3.1.5.2 Promoter CpG Methylation and Promoter Silencing; 3.1.5.3 Foreign DNA Integration into Mammalian Genomes Leads to Alterations in Methylation and Transcription Patterns; Genome-Wide Increases in DNA Methylation in Ad12-Transformed Cells-Stability of Changes Even After the Loss of All Viral Genom ... ; Alterations of Cellular DNA Methylation and Transcription Patterns Are Also Elicited in Bacteriophage Lambda or Bacterial Plas ...
  table of contents: Alterations of CpG Methylation Patterns Way Upstream of the FMR1 Boundary in Human Cells Immortalized by Epstein-Barr Virus (E ... A Model System to Study the Epigenomic Destabilization in Human Cells Transgenomic for a 5.6 kbp Bacterial Plasmid; 3.1.6 Résumé; References; Chapter 4: Epigenetic Consequences of Epstein-Barr Virus Infection; 4.1 Epigenetic Regulation of the EBV Life Cycle; 4.1.1 EBV Life Cycle; 4.1.2 Epigenetic Control of Viral Promoter Usage; 4.1.3 Epigenetic Regulation of Lytic Reactivation; 4.2 Viral Protein Interactions with the Host Epigenetic Machinery; 4.2.1 EBNA1.
  note: Walter Doerfler, Josep Casadesús, editors.
  note: Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty
  note: Includes bibliographical references.
  subject:
    topic: Communicable diseases
    topic: Genetic aspects
  subject:
    topic: Epigenetics
  related item:
    identifier: (OCoLC)972207548
  related item:
    title info:
      title: Epigenetics and human health
  identifier: 9783319550213
  identifier: 9783319550190
  identifier: https://proxy.k.utb.cz/login
  access condition: Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty
  record info:
    record content source: YDX
    record creation date: 170530
    record change date: 20251008101052.0
    record identifier: 97330
    language of cataloging:
      language term: eng